-
公开(公告)号:US07988979B2
公开(公告)日:2011-08-02
申请号:US12013047
申请日:2008-01-11
申请人: Claire M. Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Maria Rosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
发明人: Claire M. Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Maria Rosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
IPC分类号: A61K39/095 , A61K39/02 , A61K39/00 , A61K38/00 , C07K14/00
CPC分类号: C07K14/22 , A61K38/00 , A61K39/00 , A61K39/095 , A61K2039/55505 , Y10S530/806 , Y10S530/825
摘要: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
摘要翻译: 本发明提供脑膜炎奈瑟氏球菌的蛋白质,包括氨基酸序列和相应的核苷酸序列。 蛋白质被预测为用于疫苗和/或诊断的有用的抗原。
-
公开(公告)号:US20070026021A1
公开(公告)日:2007-02-01
申请号:US11395121
申请日:2006-03-31
申请人: Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Peterson , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
发明人: Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Peterson , Mariagrazia Pizza , Rino Rappuoli , Giulo Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , Craig Venter
IPC分类号: A61K39/095 , C07K14/22 , C07K16/12
摘要: This invention provides, among other things, protein, polypeptides, and fragments thereof, derived from bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto (e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments and/or nucleic acids.
摘要翻译: 本发明尤其提供衍生自脑膜炎奈瑟氏球菌B的蛋白质,多肽和其片段。还提供编码这种蛋白质,多肽和/或片段的核酸,以及与其互补的核酸(例如, 反义核酸)。 另外,本发明提供了结合蛋白质,多肽和/或片段的抗体。 本发明进一步提供用于制备用作疫苗,诊断试剂,免疫原性组合物等的蛋白质,多肽,片段和/或核酸的表达载体。 还提供了用组合物制备组合物和处理方法的方法。 本发明还提供了检测蛋白质,多肽,片段和/或核酸的方法。
-