公开(公告)号：US20170088636A1

公开(公告)日：2017-03-30

申请号：US15126893

申请日：2014-03-19

Applicant: DAICEL CORPORATION

Inventor： Tomohiro HASHIZUME ,  Shizuka UKITA ,  Shu SHIMAMOTO ,  Toshikazu NAKAMURA

IPC: C08B3/16

CPC classification number: C08B3/16

Abstract: Provided is a novel cellulose derivative having excellent water resistance. This is a cellulose acylate oxoalkanoate which is a cellulose derivative corresponding to cellulose, except with substituents replacing part or all of hydrogen atoms in the hydroxy groups of the cellulose. The substituents includes a group represented by General Formula (1) and a group represented by General Formula (2). The cellulose acylate oxoalkanoate has a degree x of substitution with the group represented by General Formula (1), a degree y of substitution with the group represented by General Formula (2), and a degree z of unsubstitution, where x, y, and z meet conditions specified by Expressions (A), (B), and (C): 0.1≦x≦2.99  (A) 0.01≦y≦2.90  (B) z=3−x−y  (C)

公开(公告)号：US20190151349A1

公开(公告)日：2019-05-23

申请号：US16258224

申请日：2019-01-25

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A61K45/06 ,  A23K20/163 ,  A23K50/30 ,  A23K50/75 ,  A23K50/10

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and [Math. 1] the theoretical value of half height width of chemical composition =2. 35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20160317568A1

公开(公告)日：2016-11-03

申请号：US15106095

申请日：2014-03-24

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A23K20/163 ,  A23K50/75

CPC classification number: A61K31/717 ,  A23K20/163 ,  A23K50/10 ,  A23K50/30 ,  A23K50/40 ,  A23K50/75 ,  A23L33/24 ,  A23V2002/00 ,  A61K45/06 ,  A61K2300/00

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Abstract translation: 其中DS是乙酰基取代的总量; DPw是通过使用通过丙酰化乙酸纤维素（样品）的所有残留羟基制备的丙酸纤维素的GPC-光散射法测定的重均聚合度。

公开(公告)号：US20170100426A1

公开(公告)日：2017-04-13

申请号：US15128682

申请日：2015-03-20

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI ,  Tatsuya MORITA ,  Tomomi GENDA

IPC: A61K31/717

CPC classification number: A61K31/717 ,  A23L33/24

Abstract: A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune disorders, cancers, non-alcoholic steatohepatitis, obesity, diabetes, and hypercholesterolemia each contain a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may be one having a compositional distribution index (CDI) of 2.0 or less, where the CDI is defined by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample), and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20160032020A1

公开(公告)日：2016-02-04

申请号：US14775369

申请日：2014-03-12

Applicant: DAICEL CORPORATION

Inventor： Shizuka UKITA ,  Hiroki TANIGUCHI ,  Shu SHIMAMOTO ,  Toshikazu NAKAMURA

IPC: C08B3/06 ,  C08B3/24

CPC classification number: C08B3/06 ,  C08B3/24 ,  C08B3/28 ,  C08J5/18 ,  C08J2301/12 ,  C08L1/12 ,  C08L1/14 ,  D01F2/28

Abstract: A cellulose acetate according to the present invention has a total degree of acetyl substitution of 0.4 to 1.1 and has a compositional distribution index (CDI) of 3.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition is a half height width of chemical composition determined by analyzing a cellulose acetate propionate by HPLC, where the cellulose acetate propionate is prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and Theoretical value of half height width of chemical composition=2·35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Abstract translation: 本发明的乙酸纤维素的总乙酰基取代度为0.4〜1.1，组成分布指数（CDI）为3.0以下，其中CDI由下式确定：CDI =（半高度的测定值 化学成分的宽度）/化学成分的半高宽度的测定值为通过HPLC分析醋酸丙酸纤维素而测定的化学成分的半高宽度的化学成分的半高宽度的理论值，其中乙酸纤维素 通过丙酰化乙酸纤维素（样品）的所有残留羟基来制备丙酸酯; （3 * DPw *（DS / 3）*（1-DS / 3））} {平方根超过（3 * DPw *（DS））的化学成分的半高宽度的理论值= 2·35482 / 3）*（1-DS / 3））} / DPw [ 1]其中DS是乙酰基取代的总量; DPw是通过使用通过丙酰化乙酸纤维素（样品）的所有残留羟基制备的丙酸纤维素的GPC-光散射法测定的重均聚合度。