SIMULATING EVOLUTION OF A TUMOR
    1.
    发明申请

    公开(公告)号:US20200027564A1

    公开(公告)日:2020-01-23

    申请号:US16504158

    申请日:2019-07-05

    Abstract: The disclosure notably relates to a computer-implemented method for simulating evolution of a tumor associated to an oncogene. The method includes providing a plurality of pieces of data, each corresponding to a given cell of the tumor, and includes a degree of activation of the oncogene in the given cell. The method further includes providing a model configured to take an input piece of data and to output information on proliferation of the respective given cell corresponding to the input piece of data. The information on proliferation depends on the degree of activation of the oncogene. The method further includes running the model on one or more pieces of data of the plurality of pieces of data and updating the plurality of pieces of data based on the result of the running. Such a method improves the simulation of the evolution of a tumor.

    CHARACTERISTICS OF PATIENT INFLUENCING DISEASE PROGESSION

    公开(公告)号:US20240203595A1

    公开(公告)日:2024-06-20

    申请号:US18544180

    申请日:2023-12-18

    CPC classification number: G16H50/20 G16H50/30 G16H50/70

    Abstract: A computer-implemented method for determining characteristics of a patient that influence a progression of a disease of the patient. The method includes, while training a neural network with a provided dataset, for each transition of the multi-state model, and for each characteristic, determining a respective quantification of an impact of the characteristic on the results of the neural network. The method includes, for each transition, identifying a list of characteristics of the set of characteristics, and, for each given characteristic of the identified list, determining a relationship between the given characteristic and probabilities of transition. The method includes providing the identified lists and the determined relationships that influence the progression of the disease of the patient. Such a method forms an improved solution for determining patient's characteristics that influence patient disease progression.

    CHARACTERISTICS OF PATIENT INFLUENCING DISEASE PROGRESSION

    公开(公告)号:US20250087352A2

    公开(公告)日:2025-03-13

    申请号:US18544180

    申请日:2023-12-18

    Abstract: A computer-implemented method for determining characteristics of a patient that influence a progression of a disease of the patient. The method includes, while training a neural network with a provided dataset, for each transition of the multi-state model, and for each characteristic, determining a respective quantification of an impact of the characteristic on the results of the neural network. The method includes, for each transition, identifying a list of characteristics of the set of characteristics, and, for each given characteristic of the identified list, determining a relationship between the given characteristic and probabilities of transition. The method includes providing the identified lists and the determined relationships that influence the progression of the disease of the patient. Such a method forms an improved solution for determining patient's characteristics that influence patient disease progression.

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