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公开(公告)号：US20090275872A1
公开(公告)日：2009-11-05
申请号：US12470620
申请日：2009-05-22
CPC分类号： A61L26/0019 , A61K31/155 , A61K31/167 , A61K31/555 , A61K31/7024 , A61K45/06 , A61L27/18 , A61K2300/00 , C08L75/04
摘要： A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.
摘要翻译： 一种包含部分固化的聚氨酯流体的伤口敷料组合物。 组合物可以直接注射到伤口中，其中它固化以形成伤口填充敷料。 还提供了包含这种组合物的伤口敷料。 还提供了用于制备这种伤口敷料的试剂盒，试剂盒包含（a）聚氨酯预聚物; 和（b）聚氨酯预聚物的固化剂。 优选地，聚氨酯组分包括二异氰酸酯与蓖麻油或蓖麻油酸或其衍生物的相关酯的反应产物。
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公开(公告)号：US08481801B2
公开(公告)日：2013-07-09
申请号：US12470620
申请日：2009-05-22
IPC分类号： A61F13/00
CPC分类号： A61L26/0019 , A61K31/155 , A61K31/167 , A61K31/555 , A61K31/7024 , A61K45/06 , A61L27/18 , A61K2300/00 , C08L75/04
摘要： A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.
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公开(公告)号：US07538257B2
公开(公告)日：2009-05-26
申请号：US10532520
申请日：2003-10-24
IPC分类号： A61F13/00
CPC分类号： A61L26/0019 , A61K31/155 , A61K31/167 , A61K31/555 , A61K31/7024 , A61K45/06 , A61L27/18 , A61K2300/00 , C08L75/04
摘要： A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.
摘要翻译： 一种包含部分固化的聚氨酯流体的伤口敷料组合物。 组合物可以直接注射到伤口中，其中它固化以形成伤口填充敷料。 还提供了包含这种组合物的伤口敷料。 还提供了用于制备这种伤口敷料的试剂盒，试剂盒包含（a）聚氨酯预聚物; 和（b）聚氨酯预聚物的固化剂。 优选地，聚氨酯组分包括二异氰酸酯与蓖麻油或蓖麻油酸或其衍生物的相关酯的反应产物。
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公开(公告)号：US20060142685A1
公开(公告)日：2006-06-29
申请号：US10532520
申请日：2003-10-24
CPC分类号： A61L26/0019 , A61K31/155 , A61K31/167 , A61K31/555 , A61K31/7024 , A61K45/06 , A61L27/18 , A61K2300/00 , C08L75/04
摘要： A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composistion. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.
摘要翻译： 一种包含部分固化的聚氨酯流体的伤口敷料组合物。 组合物可以直接注射到伤口中，其中它固化以形成伤口填充敷料。 还提供了包括这种组合物的伤口敷料。 还提供了用于制备这种伤口敷料的试剂盒，试剂盒包含（a）聚氨酯预聚物; 和（b）聚氨酯预聚物的固化剂。 优选地，聚氨酯组分包括二异氰酸酯与蓖麻油或蓖麻油酸或其衍生物的相关酯的反应产物。
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公开(公告)号：US4646730A
公开(公告)日：1987-03-03
申请号：US866541
申请日：1986-05-23
CPC分类号： A61L26/008 , A61L26/0014 , A61L26/0066 , A61L2300/104 , A61L2300/404
摘要： A polyvinylpyrrolidone(PVP)/Silver Sulfadiazine (SSD) hydrogel dressing in which the gel is formed by the use of electron beam (E-Beam) radiation to cross-link the polyvinylpyrrolidone (PVP); in which the color of the hydrogel dressing has been stabilized by the addition thereto of magnesium trisilicate and, optionally but preferably, also hydrogen peroxide and/or polyacrylic acid is disclosed; and also the process of stabilizing the color by adding magnesium trisilicate, to a water dispersion of PVP and SSD before it is exposed to E-Beam radiation is disclosed.
摘要翻译： 聚乙烯吡咯烷酮（PVP）/磺胺二嗪（SSD）水凝胶敷料，其中通过使用电子束（E-Beam）辐射形成凝胶以交联聚乙烯吡咯烷酮（PVP）; 其中水凝胶敷料的颜色已经通过加入三硅酸镁而稳定，并且任选但优选也公开了过氧化氢和/或聚丙烯酸; 并且还公开了在暴露于E-Beam辐射之前，通过加入三硅酸镁将PVP和SSD的水分散体稳定的过程。
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6.发明授权Pressure sensitive adhesive compositions for coating articles to be attached to skin 失效用于涂覆附着于皮肤的制品的压敏粘合剂组合物
公开(公告)号：US4140115A
公开(公告)日：1979-02-20
申请号：US580371
申请日：1975-05-23
申请人： Edward Schonfeld
发明人： Edward Schonfeld
CPC分类号： A61L15/58 , A61F13/0253 , A61L15/20 , C08L33/26 , Y10T428/31504
摘要： Skin damage, i.e., the stripping of tissue cells from the stratum corneum, caused by removal of a backing material which has been held in adherent contact with a skin surface by means of a pressure sensitive adhesive composition coated on the backing material, is markedly reduced by incorporation of about 4 to 20% by weight of an unreacted polyol uniformly dispersed in the water-insoluble pressure sensitive adhesive mass. Suitable polyols include polyethylene glycol and polypropylene sorbitol monolaurate. This improved mass finds special application for use in conjunction with adhesive bandages or rolled tapes composed of a backing material of a plasticized film of polyvinyl chloride. Remarkably, the reduction in skin damage is accomplished without sacrificing low mass transfer to skin upon removal of the backing material, cohesive strength, adhesion, or wearability, all of which are highly desirable properties of pressure sensitive adhesive tapes and bandages.
摘要翻译： 通过去除已经通过涂覆在背衬材料上的压敏粘合剂组合物与皮肤表面保持接触的背衬材料引起的皮肤损伤，即从角质层剥离组织细胞，显着降低 通过加入约4至20重量％的均匀分散在水不溶性压敏粘合剂中的未反应的多元醇。 合适的多元醇包括聚乙二醇和聚山梨醇单月桂酸酯。 这种改进的质量发现与粘合绷带或由聚氯乙烯增塑膜的背衬材料组成的卷带一起使用的特殊应用。 值得注意的是，在去除背衬材料，内聚强度，粘合力或耐磨性的同时，不会牺牲皮肤的低质量转移，所有这些都是压敏粘合带和绷带的高度期望的性能，可以实现皮肤损伤的减少。
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