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1.发明授权Gelatin encapsulated oral care composition containing hydrophilic active, hydrophobic structuring agent and oil carrier 有权明胶包封口腔护理组合物含有亲水性活性，疏水性结构剂和油载体公开(公告)号：US09320690B2
公开(公告)日：2016-04-26
申请号：US13995543
申请日：2010-12-20
CPC分类号： A61K8/11 , A46B11/0003 , A46B2200/1066 , A61K8/31 , A61K8/375 , A61K8/4926 , A61K8/8111 , A61Q11/00
摘要： An encapsulated oral care composition includes: (a) a gelatin capsule; and (b) a oral care composition contained within the capsule, and including: (i) a hydrophilic active; (ii) a hydrophobic structuring agent; and (iii) an oil carrier. The hydrophilic active is preferably cetylpyridinium chloride. The hydrophobic structuring agent is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the encapsulated oral care composition such that the capsule releases the oral care composition to clean the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and the encapsulated oral care composition positioned on the head.
摘要翻译： 包封的口腔护理组合物包括：（a）明胶胶囊; 和（b）包含在胶囊内的口腔护理组合物，包括：（i）亲水性活性物质; （ii）疏水结构剂; 和（iii）油载体。 亲水性活性剂优选氯化十六烷基吡啶鎓。 疏水结构剂优选为凝胶状矿物油。 油载体优选为植物油。 清洁牙齿的方法包括将包封的口腔护理组合物施用于牙齿，使得胶囊释放口腔护理组合物以清洁牙齿。 口腔护理器具包括：手柄; 头部，其安装到手柄上，头部具有外表面和从外表面向外延伸的多个牙齿清洁元件; 和封装在头上的口腔护理组合物。
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2.发明申请Gelatin Encapsulated Oral Care Composition Containing Hydrophilic Active, Hydrophobic Structuring Agent and Oil Carrier 有权含有亲水活性，疏水性结构剂和油载体的明胶包封口腔护理组合物公开(公告)号：US20130269133A1
公开(公告)日：2013-10-17
申请号：US13995543
申请日：2010-12-20
CPC分类号： A61K8/11 , A46B11/0003 , A46B2200/1066 , A61K8/31 , A61K8/375 , A61K8/4926 , A61K8/8111 , A61Q11/00
摘要： An encapsulated oral care composition includes: (a) a gelatin capsule; and (b) a oral care composition contained within the capsule, and including: (i) a hydrophilic active; (ii) a hydrophobic structuring agent; and (iii) an oil carrier. The hydrophilic active is preferably cetylpyridinium chloride. The hydrophobic structuring agent is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the encapsulated oral care composition such that the capsule releases the oral care composition to clean the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and the encapsulated oral care composition positioned on the head.
摘要翻译： 包封的口腔护理组合物包括：（a）明胶胶囊; 和（b）包含在胶囊内的口腔护理组合物，包括：（i）亲水性活性物质; （ii）疏水结构剂; 和（iii）油载体。 亲水性活性剂优选氯化十六烷基吡啶鎓。 疏水结构剂优选为凝胶状矿物油。 油载体优选为植物油。 清洁牙齿的方法包括将包封的口腔护理组合物施用于牙齿，使得胶囊释放口腔护理组合物以清洁牙齿。 口腔护理器具包括：手柄; 头部，其安装到手柄上，头部具有外表面和从外表面向外延伸的多个牙齿清洁元件; 和封装在头上的口腔护理组合物。
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3.发明授权Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier 有权明胶包封的口腔护理组合物含有牙科堵塞活性物质，疏水性粘度调节剂和油载体公开(公告)号：US09161891B2
公开(公告)日：2015-10-20
申请号：US13995512
申请日：2010-12-20
申请人： Dennis Kembero Ontumi , Sarita Vera Mello , Suman Kumar Chopra , James Richard Brown , Thomas James Boyd , Rahul Patel
发明人： Dennis Kembero Ontumi , Sarita Vera Mello , Suman Kumar Chopra , James Richard Brown , Thomas James Boyd , Rahul Patel
CPC分类号： A61K8/11 , A46B11/001 , A61K8/31 , A61K8/44 , A61K8/65 , A61K8/8111 , A61K8/8164 , A61K8/922 , A61K2800/31 , A61Q11/00
摘要： A oral care composition includes: (a) a guanidine active; (b) a film-forming polymer; (c) a hydrophobic viscosity modifier in an amount sufficient to provide the oral care composition with a particle settling time greater than 20 minutes; and (d) an oil carrier. The guanidine active is preferably L-arginine. The film-forming polymer is preferably GANTREZ. The hydrophobic viscosity modifier is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the oral care composition cleans the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.
摘要翻译： 口腔护理组合物包括：（a）活性的胍; （b）成膜聚合物; （c）疏水性粘度调节剂，其量足以使口腔护理组合物的沉降时间大于20分钟; 和（d）油载体。 胍活性剂优选为L-精氨酸。 成膜聚合物优选为GANTREZ。 疏水性粘度调节剂优选为凝胶状矿物油。 油载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得口腔护理组合物清洁牙齿。 口腔护理器具包括：手柄; 头部，其安装到手柄上，头部具有外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。
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4.发明申请Gelatin Encapsulated Oral Care Composition Containing Dental Occlusion Actives, Hydrophobic Viscosity Modifier and Oil Carrier 有权明胶包封口腔护理组合物含有牙科闭塞活性物质，疏水性粘度调节剂和油载体公开(公告)号：US20130269132A1
公开(公告)日：2013-10-17
申请号：US13995512
申请日：2010-12-20
申请人： Dennis Kembero Ontumi , Sarita Vera Mello , Suman Kumar Chopra , James Richard Brown , Thomas James Boyd , Rahul Patel
发明人： Dennis Kembero Ontumi , Sarita Vera Mello , Suman Kumar Chopra , James Richard Brown , Thomas James Boyd , Rahul Patel
CPC分类号： A61K8/11 , A46B11/001 , A61K8/31 , A61K8/44 , A61K8/65 , A61K8/8111 , A61K8/8164 , A61K8/922 , A61K2800/31 , A61Q11/00
摘要： A oral care composition includes: (a) a guanidine active; (b) a film-forming polymer; (c) a hydrophobic viscosity modifier in an amount sufficient to provide the oral care composition with a particle settling time greater than 20 minutes; and (d) an oil carrier. The guanidine active is preferably L-arginine. The film-forming polymer is preferably GANTREZ. The hydrophobic viscosity modifier is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the oral care composition cleans the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.
摘要翻译： 口腔护理组合物包括：（a）活性的胍; （b）成膜聚合物; （c）疏水性粘度调节剂，其量足以使口腔护理组合物的沉降时间大于20分钟; 和（d）油载体。 胍活性剂优选为L-精氨酸。 成膜聚合物优选为GANTREZ。 疏水性粘度调节剂优选为凝胶状矿物油。 油载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得口腔护理组合物清洁牙齿。 口腔护理器具包括：把手; 头部，其安装到手柄上，头部具有外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。
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5.发明授权公开(公告)号：US09289369B2
公开(公告)日：2016-03-22
申请号：US13995440
申请日：2010-12-20
申请人： Thomas James Boyd , Suman Kumar Chopra , Sarita Vera Mello , Rahul Patel , Dennis Kembero Ontumi
发明人： Thomas James Boyd , Suman Kumar Chopra , Sarita Vera Mello , Rahul Patel , Dennis Kembero Ontumi
CPC分类号： A61K8/8164 , A61K8/11 , A61K8/24 , A61K8/44 , A61K8/65 , A61K8/922 , A61K2800/31 , A61Q11/00
摘要： A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.
摘要翻译： 口腔护理组合物包括：（a）亲水成膜聚合物; 和（b）疏水载体，其中所述亲水成膜聚合物是有效闭塞牙质小管的成膜聚合物，并且口腔护理组合物含有0-10wt。 ％ 水。 亲水性成膜聚合物优选为GANTREZ S.疏水载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得亲水成膜聚合物封闭牙质小管。 牙刷包括：手柄; 头部，其安装到手柄上，头部包括外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。
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6.发明申请公开(公告)号：US20130263395A1
公开(公告)日：2013-10-10
申请号：US13995440
申请日：2010-12-20
申请人： Thomas James Boyd , Suman Kumar Chopra , Sarita Vera Mello , Rahul Patel , Dennis Kembero Ontumi
发明人： Thomas James Boyd , Suman Kumar Chopra , Sarita Vera Mello , Rahul Patel , Dennis Kembero Ontumi
CPC分类号： A61K8/8164 , A61K8/11 , A61K8/24 , A61K8/44 , A61K8/65 , A61K8/922 , A61K2800/31 , A61Q11/00
摘要： A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.
摘要翻译： 口腔护理组合物包括：（a）亲水成膜聚合物; 和（b）疏水载体，其中所述亲水成膜聚合物是有效闭塞牙质小管的成膜聚合物，并且口腔护理组合物含有0-10wt。 ％ 水。 亲水性成膜聚合物优选为GANTREZ S.疏水载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得亲水成膜聚合物封闭牙质小管。 牙刷包括：手柄; 头部，其安装到手柄上，头部包括外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。
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公开(公告)号：US09072371B2
公开(公告)日：2015-07-07
申请号：US13254447
申请日：2010-12-16
申请人： Eduardo Jimenez , Sharon Kennedy , Robert Moskovich , John Gatzemeyer , Gary L. Berge , Suman Kumar Chopra
发明人： Eduardo Jimenez , Sharon Kennedy , Robert Moskovich , John Gatzemeyer , Gary L. Berge , Suman Kumar Chopra
CPC分类号： A46B9/04 , A45D34/04 , A45D40/04 , A46B5/0095 , A46B5/021 , A46B11/0024 , A46B11/0027 , A46B11/0034 , A46B11/0065 , A46B2200/1066 , A61C17/227 , A61C19/066 , Y10T29/49826
摘要： An oral care system and method for applying a fluid to an oral surface, including a method of manufacturing the same. In one embodiment, the invention can be an oral care system comprising: a toothbrush; and a dispenser detachably coupled to the toothbrush, the dispenser comprising: an internal reservoir containing a fluid; and a conduit in fluid communication with the reservoir and terminating in an orifice for dispensing the fluid; and a plug having a proximal plug portion disposed within the conduit and a distal plug portion disposed within a socket of the toothbrush.
摘要翻译： 一种口腔护理系统和将流体施用于口腔表面的方法，包括其制造方法。 在一个实施例中，本发明可以是口腔护理系统，包括：牙刷; 以及可拆卸地联接到所述牙刷的分配器，所述分配器包括：容纳流体的内部容器; 以及与储存器流体连通并终止于用于分配流体的孔口的导管; 以及插塞，其具有设置在所述导管内的近侧插塞部分和设置在所述牙刷的插座内的远端插塞部分。
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公开(公告)号：US5672740A
公开(公告)日：1997-09-30
申请号：US465778
申请日：1995-06-06
IPC分类号： C07C303/02 , C07C303/44 , C07C309/10 , C07C305/00
CPC分类号： C07C303/44 , C07C303/02
摘要： A process for preparing alkoxylated alkyl glyceryl ether sulfonates which comprises reacting in the presence of water and the absence of ethanol a mixture of alkoxylated glycidyl ethers having as the major quantity of alkoxylated material ##STR1## with a salt of a sulfite bisulfite salt mixture at a temperature below about 110.degree. C. wherein R is an alkyl or alkenyl of 10 to 20 carbon atoms, inclusive, R' is hydrogen or methyl and n has an average value of 1 to 10 and obtaining a sulfonated alkoxylated product having as a major quantity of the alkoxylated material a salt of R(OCH.sub.2 CHR.sup.1).sub.n OCH.sub.2 CHOHCH.sub.2 SO.sub.3 -
摘要翻译： 一种制备烷氧基化烷基甘油醚磺酸盐的方法，其包括在水和不存在乙醇存在下，将烷氧基化缩水甘油醚与烷基化亚硫酸氢盐混合物的盐在一个 温度低于约110℃，其中R为10-20个碳原子的烷基或烯基，包括端值，R'为氢或甲基，n的平均值为1至10，得到主要量的磺化烷氧基化产物 的烷氧基化物质是R（OCH 2 CHR 1）n OCH 2 CHOHCH 2 SO 3 -
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公开(公告)号：US06403067B1
公开(公告)日：2002-06-11
申请号：US09575483
申请日：2000-05-19
申请人： Thomas Schamper , Suman Kumar Chopra , Bhal Moghe , John Carl-Frederick Brahms , Mardoqueo Bustos , Peter Hilliard, Jr. , Marie Johansson , Claudo Ortiz , Christine Popoff
发明人： Thomas Schamper , Suman Kumar Chopra , Bhal Moghe , John Carl-Frederick Brahms , Mardoqueo Bustos , Peter Hilliard, Jr. , Marie Johansson , Claudo Ortiz , Christine Popoff
IPC分类号： A61K732
摘要： Low water emulsions are described which are useful for antiperspirants and/or deodorants wherein the emulsions are made by combining (I) 15-33% of an external phase comprising: (a) 1-25% of an organic ester having a refractive index in the range of 1.43-1.60 and capable of releasing an antiperspirant active to achieve a specified conductivity; (b) a sufficient amount of a silicone copolyol to achieve a solids content of 0.25-10%; (c) a sufficient amount of a volatile silicone to achieve a total amount of the external phase as 15-33%; (c) 0-5% of a silicone elastomer (on an actives basis); and (d) 0-15% of at least one emollient; and (II) 67-85% of an internal phase comprising: (a) an effective amount of at least one cosmetically active ingredient; (b) a sufficient amount of a solvent component to dissolve the cosmetically active ingredient with a maximum amount being about 80%; (c) 0.5-15 % of water optionally containing up to 30% of an ionizable salt soluble in water; (d) 0-5 % of a non-ionic emulsifier; and (e) 0-10% ethanol; wherein: (1) the final refractive index of the composition is in the range of 1.42-1.52; and (2) the conductance of the composition is at least 250 micro Siemens/cm/ml at a loading of at least 7% by weight level of antiperspirant active.
摘要翻译： 描述了可用于止汗剂和/或除臭剂的低水乳剂，其中乳液通过将（I）15-33％的外相组合制备，所述外相包含：（a）1-25％的具有折射率的有机酯 范围为1.43-1.60，能够释放止汗活性物质达到规定的电导率; （b）足够量的硅氧烷共聚多元醇以获得0.25-10％的固体含量; （c）足量的挥发性硅酮，以达到外相总量的15-33％; （c）0-5％的硅氧烷弹性体（基于活性物质）; 和（d）至少一种润肤剂的0-15％; 和（II）67-85％的内相，其包含：（a）有效量的至少一种化妆品活性成分; （b）足够量的溶剂组分以最大量为约80％溶解化妆品活性成分; （c）0.5-15％的水，任选地含有最多30％的可溶于水的可电离盐; （d）0-5％的非离子乳化剂; 和（e）0-10％乙醇; 其中：（1）组合物的最终折射率在1.42-1.52的范围内; 和（2）组合物的电导率至少为250微西门子/厘米/毫升，以至少7重量％的止汗活性剂的负荷。
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公开(公告)号：US20130251772A1
公开(公告)日：2013-09-26
申请号：US13992273
申请日：2010-12-07
申请人： Suman Kumar Chopra , Rahul Patel
发明人： Suman Kumar Chopra , Rahul Patel
CPC分类号： A61K8/25 , A61K8/044 , A61K2800/412 , A61Q11/00 , C01B33/24 , C01P2004/61 , C01P2004/62 , C01P2006/12
摘要： An oral care composition includes an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits.
摘要翻译： 口腔护理组合物包含有效量的硅酸钙颗粒。 硅酸钙颗粒的平均直径小于约5微米，使得它们可以堵塞牙齿的牙质小管。 口腔护理方法包括将组合物施用于受试者的口腔以减少或抑制牙齿的超敏反应并实现其它益处。
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