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公开(公告)号：US11084851B2
公开(公告)日：2021-08-10
申请号：US16113403
申请日：2018-08-27
Applicant: EMD Millipore Corporation
Inventor： Nanying Bian , Neil Soice , Shari Spector , Kara Levine
IPC: C07K14/31 , B01D15/38 , B01J20/286 , B01J20/32
Abstract: The present invention relates to chromatography ligands having improved caustic stability, e.g., ligands based on immunoglobulin-binding proteins such as, Staphylococcal protein A, as well as methods of making and using such ligands.
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公开(公告)号：US09376474B1
公开(公告)日：2016-06-28
申请号：US14970610
申请日：2015-12-16
Applicant: EMD Millipore Corporation
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
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3.发明授权Chromatography matrices including novel Staphylococcus aureus protein A based ligands 有权色谱基质包括新型金黄色葡萄球菌蛋白A基配体公开(公告)号：US09234010B2
公开(公告)日：2016-01-12
申请号：US14683738
申请日：2015-04-10
Applicant: EMD Millipore Corporation
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
Abstract translation: 本发明涉及包括基于免疫球蛋白结合蛋白（例如金黄色葡萄球菌蛋白A（SpA））的一个或多个结构域的配体的色谱基质，以及使用它们的方法。
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公开(公告)号：US20160168194A1
公开(公告)日：2016-06-16
申请号：US14970610
申请日：2015-12-16
Applicant: EMD Millipore Corporation
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
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公开(公告)号：US20210388036A1
公开(公告)日：2021-12-16
申请号：US17388090
申请日：2021-07-29
Applicant: EMD Millipore Corporation
Inventor： Nanying Bian , Neil Soice , Shari Spector , Kara Levine
IPC: C07K14/31 , B01D15/38 , B01J20/286 , B01J20/32
Abstract: The present invention relates to chromatography ligands having improved caustic stability, e.g., ligands based on immunoglobulin-binding proteins such as, Staphylococcal protein A, as well as methods of making and using such ligands.
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Patent Agency Ranking
6.发明申请CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS 有权包含新型葡萄球菌蛋白酶基因配体的色谱图公开(公告)号：US20150080558A1
公开(公告)日：2015-03-19
申请号：US14534999
申请日：2014-11-06
Applicant: EMD MILLIPORE CORPORATION
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
Abstract translation: 本发明涉及包括基于免疫球蛋白结合蛋白（例如金黄色葡萄球菌蛋白A（SpA））的一个或多个结构域的配体的色谱基质，以及使用它们的方法。
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7.发明授权Chromatography matrices including novel Staphylococcus aureus protein A based ligands 有权色谱基质包括新型金黄色葡萄球菌蛋白A基配体公开(公告)号：US08895706B2
公开(公告)日：2014-11-25
申请号：US14298332
申请日：2014-06-06
Applicant: EMD Millipore Corporation
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylooccus aureus Protein A (SpA), as well as methods of using the same.
Abstract translation: 本发明涉及包括基于免疫球蛋白结合蛋白的一个或多个结构域的配体的色谱基质，例如金黄色葡萄球菌蛋白A（SpA），以及使用它们的方法。
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8.发明申请CHROMATOGRAPHY MATRICES INCLUDING NOVEL STAPHYLOCOCCUS AUREUS PROTEIN A BASED LIGANDS 有权包含新型葡萄球菌蛋白酶基因配体的色谱图公开(公告)号：US20140296434A1
公开(公告)日：2014-10-02
申请号：US14298332
申请日：2014-06-06
Applicant: EMD Millipore Corporation
Inventor： Shari Spector , Robert Smith , Joe Orlando , Nanying Bian
CPC classification number: C07K14/31 , B01D15/3809 , B01J20/286 , B01J20/3272 , B01J20/3274 , C07K1/22 , C07K16/1271 , C07K2319/21
Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
Abstract translation: 本发明涉及包括基于免疫球蛋白结合蛋白（例如金黄色葡萄球菌蛋白A（SpA））的一个或多个结构域的配体的色谱基质，以及使用它们的方法。
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公开(公告)号：US20180362595A1
公开(公告)日：2018-12-20
申请号：US16113403
申请日：2018-08-27
Applicant: EMD Millipore Corporation
Inventor： Nanying Bian , Neil Soice , Shari Spector , Kara Levine
IPC: C07K14/31 , B01J20/32 , B01D15/38 , B01J20/286
Abstract: The present invention relates to chromatography ligands having improved caustic stability, e.g., ligands based on immunoglobulin-binding proteins such as, Staphylococcal protein A, as well as methods of making and using such ligands.
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公开(公告)号：US09920112B2
公开(公告)日：2018-03-20
申请号：US14061080
申请日：2013-10-23
Applicant: EMD Millipore Corporation
Inventor： Shari Spector
IPC: C07K16/12 , C07K1/22 , C07K14/31 , B01J20/286 , B01J20/32
CPC classification number: C07K16/1271 , B01J20/286 , B01J20/3274 , C07K1/22 , C07K14/31
Abstract: The present invention relates to modified immunoglobulin-binding proteins, e.g., Staphylococcus protein A, having improved binding specificity for immunoglobulins and methods of making and using the same.
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