APPARATUS AND METHOD FOR NANO MAGNETIC PARTICLE IMAGING

    公开(公告)号:US20210405134A1

    公开(公告)日:2021-12-30

    申请号:US17318753

    申请日:2021-05-12

    Abstract: Disclosed herein is a nano-magnetic-particle-imaging apparatus, including a measurement head including excitation and detection coils and accommodating a sample bed for a sample including nano magnetic particles; a gradient magnetic field generation unit for generating a magnetic field having a strength equal to or greater than that of the saturation magnetic field of the nano magnetic particles in a spacing area between identical magnetic poles facing each other and forming a field-free region in a portion thereof; a first driving unit for linearly moving the sample bed; a second driving unit for rotating the gradient magnetic field generation unit in a plane; a third driving unit for linearly reciprocating the gradient magnetic field generation unit; and a control unit for applying a signal to the excitation coil, controlling the driving units, and imaging 3D distribution of the nano magnetic particles based on a detection signal output from the detection coil.

    APPARATUS FOR ACQUIRING LOCATION COORDINATES OF OBJECT USING TWO MEASUREMENT HEADS AND METHOD USING THE SAME
    3.
    发明申请
    APPARATUS FOR ACQUIRING LOCATION COORDINATES OF OBJECT USING TWO MEASUREMENT HEADS AND METHOD USING THE SAME 审中-公开
    用于使用两个测量头获取对象的位置坐标的装置和使用该测量头的方法

    公开(公告)号:US20170067730A1

    公开(公告)日:2017-03-09

    申请号:US15183639

    申请日:2016-06-15

    CPC classification number: G01B7/004

    Abstract: Disclosed herein are an apparatus for acquiring the location coordinates of an object to be measured using two measurement heads and a method using the apparatus. The apparatus for acquiring the location coordinates of an object includes two measurement heads for individually detecting a signal corresponding to the object to be measured, a measurement head fixing unit for placing the two measurement heads so as to face each other with the object therebetween, a rotatable structure for rotating the measurement head fixing unit, and a location determination unit for acquiring the location coordinates of the object to be measured based on the strengths of the two detection signals detected by the measurement heads.

    Abstract translation: 这里公开了一种用于使用两个测量头获取待测物体的位置坐标的装置和使用该装置的方法。 用于获取物体的位置坐标的装置包括用于分别检测与待测物体相对应的信号的两个测量头,用于将两个测量头彼此面对地放置在一起的测量头固定单元, 用于旋转测量头固定单元的可旋转结构;以及位置确定单元,用于基于由测量头检测到的两个检测信号的强度来获取待测对象的位置坐标。

    METHOD FOR SCANNING MULTILAYER MATERIAL USING MAGNETISM AND APPARATUS USING THE SAME

    公开(公告)号:US20180202973A1

    公开(公告)日:2018-07-19

    申请号:US15870565

    申请日:2018-01-12

    CPC classification number: G01N27/902 G01N27/82 G01N27/9033

    Abstract: Disclosed herein are a method and apparatus for scanning a multilayer material using magnetism. The apparatus for scanning a multilayer material includes at least one measurement head for exciting a mixed magnetic field on a multilayer specimen using at least one excitation solenoid coil and detecting detection signals from the multilayer specimen using a detection solenoid coil, a movement controller for moving any one of the at least one measurement head and a stage on which the multilayer specimen is placed in order to detect detection signals for all parts of the multilayer specimen, and a signal controller for generating two excitation signals having different frequencies in order to generate the mixed magnetic field and for generating a scanning result for the multilayer specimen by collecting the detection signals.

    METHOD OF DIAGNOSING ALZHEIMERS DISEASE USING SALIVA
    7.
    发明申请
    METHOD OF DIAGNOSING ALZHEIMERS DISEASE USING SALIVA 审中-公开
    使用SALIVA诊断阿尔茨海默病的方法

    公开(公告)号:US20140057364A1

    公开(公告)日:2014-02-27

    申请号:US13801925

    申请日:2013-03-13

    Abstract: Provided is a method of diagnosing Alzheimer's disease. The method of diagnosing Alzheimer's disease includes preparing magnetic particles having primary capture antibodies specifically bonded with beta-amyloid adsorbed thereon, introducing saliva containing beta-amyloid into the magnetic particles to bond the beta-amyloid contained in the saliva with the primary capture antibodies, bonding secondary capture antibodies labeled with fluorescent substances to the magnetic particles bonded with the beta-amyloid to form a complex, disposing the complex in a channel region of an photoelectric conversion device in which photoelectric current is changed according to an amount of incident light, and measuring photoelectric current changed by light excited from the complex to quantify a concentration of the beta-amyloid contained in the saliva.

    Abstract translation: 提供了一种诊断阿尔茨海默病的方法。 诊断阿尔茨海默病的方法包括制备具有与其上吸附的β-淀粉样蛋白特异性结合的初级捕获抗体的磁性颗粒,将含有β-淀粉样蛋白的唾液引入磁性颗粒中以将含有唾液中的β-淀粉样蛋白与初级捕获抗体结合,键合 用荧光物质标记的二次捕获抗体与β-淀粉样蛋白结合的磁性颗粒形成复合物,将该复合物置于光电转换装置的通道区域中,其中光电流根据入射光量而改变,并测量 由络合物激发光的光电流变化,以量化唾液中所含β-淀粉样蛋白的浓度。

    METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE USING BIOMATERIAL
    8.
    发明申请
    METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE USING BIOMATERIAL 有权
    使用生物材料诊断阿尔茨海默病的方法

    公开(公告)号:US20130337466A1

    公开(公告)日:2013-12-19

    申请号:US13843574

    申请日:2013-03-15

    CPC classification number: G01N33/6896 G01N33/54326 G01N33/54373

    Abstract: Provided is a method for diagnosing Alzheimer/s disease using a decomposed biomaterial. The method includes: preparing magnetic particles on which primary capture antibodies specifically bound to beta-amyloid are adsorbed; decomposing a biomaterial including beta-amyloid; binding the beta-amyloid to the primary capture antibodies; binding secondary capture antibodies labeled with a fluorescent material to the magnetic particles bound to the beta-amyloid to form a complex; disposing the complex in a channel region of a photo field effect transistor in which a photocurrent is changed according to the amount of incident light; and measuring the photocurrent changed by light excited from the complex to quantify the concentration of the beta-amyloid existing in the biomaterial.

    Abstract translation: 提供了使用分解生物材料诊断阿尔茨海默病的方法。 该方法包括:制备其上吸附了特异性结合β-淀粉样蛋白的初级捕获抗体的磁性颗粒; 分解包括β-淀粉样蛋白在内的生物材料; 将β-淀粉样蛋白与初级捕获抗体结合; 用荧光材料标记的结合二次捕获抗体结合到β-淀粉样蛋白上形成复合物的磁性颗粒; 将复合物设置在光电流根据入射光量变化的光电场效应晶体管的沟道区域中; 并测量由络合物激发的光改变的光电流,以量化存在于生物材料中的β-淀粉样蛋白的浓度。

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