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公开(公告)号:US07799822B2
公开(公告)日:2010-09-21
申请号:US11643622
申请日:2006-12-21
申请人: Esther Martinborough , Lev T. D. Fanning , Urvi Sheth , Dean Wilson , Andreas Termin , Timothy Neubert , Nicole Zimmermann , Tara Knoll , Tara Whitney , Aarti Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Gutierrez
发明人: Esther Martinborough , Lev T. D. Fanning , Urvi Sheth , Dean Wilson , Andreas Termin , Timothy Neubert , Nicole Zimmermann , Tara Knoll , Tara Whitney , Aarti Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Gutierrez
IPC分类号: A01N43/36
CPC分类号: C07D417/12 , C07D239/42 , C07D401/12 , C07D405/12 , C07D417/14 , C07D471/10 , C07D491/10
摘要: The present invention relates to phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.
摘要翻译: 本发明涉及可用作离子通道抑制剂的苯基磺酰胺。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病(包括例如治疗疼痛)的方法。
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2.
公开(公告)号:US07855220B2
公开(公告)日:2010-12-21
申请号:US11517754
申请日:2006-09-08
IPC分类号: A61K31/426 , A61K31/4245 , A61K31/425 , C07D277/52 , C07D271/07 , C07D271/113 , C07D275/03
CPC分类号: C07D417/12 , C07D277/52
摘要: Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了用作离子通道拮抗剂的双环衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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3.
公开(公告)号:US20070203130A1
公开(公告)日:2007-08-30
申请号:US11517754
申请日:2006-09-08
IPC分类号: A61K31/541 , A61K31/5377 , A61K31/53 , A61K31/501 , A61K31/497 , A61K31/496 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号: C07D417/12 , C07D277/52
摘要: Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了用作离子通道拮抗剂的双环衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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公开(公告)号:US20070117801A1
公开(公告)日:2007-05-24
申请号:US11450695
申请日:2006-06-09
IPC分类号: A61K31/53 , A61K31/50 , A61K31/433 , A61K31/4245 , A61K31/415 , A61K31/42
CPC分类号: C07D277/52 , C07C311/46 , C07C311/47 , C07C2602/08 , C07D417/12
摘要: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作离子通道抑制剂的二氢化茚衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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