公开(公告)号：US20160122516A1

公开(公告)日：2016-05-05

申请号：US14991551

申请日：2016-01-08

Applicant: FUJIFILM Corporation

Inventor： Masaki NORO ,  Yutaka NOZOE ,  Hiroshi INADA ,  Naoya SHIMOJU ,  Aiko YOSHIDA ,  Yu NAITO ,  Yasukazu KUWAYAMA

IPC: C08L1/12 ,  G02B5/30 ,  G02F1/1335 ,  G02B1/14

CPC classification number: C08L1/12 ,  C08K5/3462 ,  C08L1/10 ,  G02B1/14 ,  G02B5/3033 ,  G02B5/305 ,  G02F1/133528 ,  Y10T428/105

Abstract: The inventions are an optical film containing cellulose acylate and a compound having a structure denoted by General Formula (A) described below, and a polarizing plate and a liquid crystal display device employing the optical film. L represents n-valent connecting group, n represents an integer of greater than or equal to 2, and A represents a heterocyclic group denoted by General Formula (I). R1, R3, and R5 represent a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an aryl group, or a heteroaryl group. Here, any one of R1, R3, and R5 is bonded to L.

Abstract translation: 本发明是含有纤维素酰化物和具有下述通式（A）表示的结构的化合物的光学膜，以及使用该光学膜的偏光板和液晶显示装置。 L表示n价连接基，n表示大于或等于2的整数，A表示通式（I）表示的杂环基。 R 1，R 3和R 5表示氢原子，烷基，环烷基，烯基，芳基或杂芳基。 这里，R 1，R 3和R 5中的任一个与L结合。

公开(公告)号：US20130120839A1

公开(公告)日：2013-05-16

申请号：US13675615

申请日：2012-11-13

Applicant: FUJIFILM CORPORATION

Inventor： Nobutaka FUKAGAWA ,  Masaki NORO ,  Shuuji KANAYAMA ,  Hiroshi INADA

IPC: C09K19/02 ,  C08L1/10 ,  G02B5/30 ,  B32B23/04

CPC classification number: C09K19/02 ,  B32B23/04 ,  C08L1/10 ,  G02B5/30 ,  G02B5/3025 ,  Y10T428/105 ,  Y10T428/31986

Abstract: There is provided a cellulose acylate film, containing a hindered amin-based compound, wherein the hindered amine-based compound is contained in an amount of 0.001% by mass to 5% by mass based on cellulose acylate, a minimum value of Knoop hardness is 170 N/mm2 to 220 N/mm2, and the Knoop hardness is measured several times by a Knoop indenter, the Knoop indenter is rotated by a given angle in each measurement, and a rotation axis of the Knoop indenter is orthogonal to an upper surface of the cellulose acylate film.

Abstract translation: 提供了含有受阻胺基化合物的纤维素酰化物膜，其中受阻胺类化合物的含量相对于纤维素酰化物为0.001质量％至5质量％，诺普硬度的最小值为 170N / mm 2至220N / mm 2，并且通过Knoop压头测量Knoop硬度，在每次测量中将Knoop压头旋转给定角度，并且Knoop压头的旋转轴线正交于上表面 的纤维素酰化物膜。

公开(公告)号：US20220273817A1

公开(公告)日：2022-09-01

申请号：US17743584

申请日：2022-05-13

Applicant: FUJIFILM Corporation

Inventor： Takahiro SEKIGUCHI ,  Taisuke ENDO ,  Shun KANEUMI ,  Masaki NORO ,  Shintaro TANABE ,  Masahiko YAMAMOTO

IPC: A61K48/00 ,  A61K47/28 ,  A61K47/10 ,  A61K47/14

Abstract: An object of the present invention is to provide a lipid composition capable of achieving excellent nucleic acid delivery for a wide variety of nucleic acids. According to the present invention, there is provided a lipid composition containing a first lipid which is a lipid represented by Formula (1) or a salt thereof, sterols, and nucleic acid, in which a ratio of the number of moles of the first lipid in the lipid composition to the number of moles of sterols in the lipid composition is 0.300 or more and less than 1.299. In the formula, X represents —NR1— or —O—, R1 represents a hydrogen atom, a hydrocarbon group, or the like, R2 and R3 each independently represent a hydrogen atom, a hydrocarbon group, or the like, R4, R5, R6, R7, R8, R9, R10, R11, and R12 each independently represent a hydrogen atom or an alkyl group, groups in any one or more pairs among R4 and R5, R10 and R5, R5 and R12, R4 and R6, R5 and R6, R6 and R7, R6 and R10, R12 and R7, and R7 and R8 may be linked to each other to form a 4- to 7-membered ring which may contain an O atom, a, b, c, and d are each independently represent an integer of 0 to 3, a+b is 1 or more, and c+d is 1 or more.

公开(公告)号：US20160060406A1

公开(公告)日：2016-03-03

申请号：US14843757

申请日：2015-09-02

Applicant: FUJIFILM Corporation

Inventor： Hiroshi INADA ,  Naozumi SHIRAIWA ,  Yingjie XU ,  Yasukazu KUWAYAMA ,  Nobutaka FUKAGAWA ,  Masaki NORO

IPC: C08J5/18 ,  G02B5/30 ,  G02F1/1335

CPC classification number: C08J5/18 ,  C08J2301/10 ,  C08J2301/12 ,  G02B5/3033 ,  G02F1/133528 ,  Y10T428/105

Abstract: The cellulose acylate film includes a compound denoted by formula 1 below: wherein, in formula 1, Het denotes an optionally substituted aromatic hetero ring; X1 denotes a single bond or a group selected from the group consisting of —O—, —NR2—, —CR3R4—, —S—, and —CO—; each of R2, R3, and R4 independently denotes a hydrogen atom or a substituent; R1 denotes a partial structure of valence n, with n denoting an integer greater than or equal to 1; wherein the compound includes at least one group selected from the group consisting of —NH— and —CO— per molecule, and at least one group selected from the group consisting of —X2—(C═X4)—X3—, —NR5—(SO2)—, —CO—NR6—CO—, —O—, —S—, —COOH, —CN, —NR7R8, —OH, and —SH per molecule.

Abstract translation: 纤维素酰化物膜包括由下式1表示的化合物：其中，在式1中，Het表示任选取代的芳族杂环; X1表示单键或选自-O - ， - NR2-，-CR 3 R 4 - ， - S-和-CO-的基团。 R2，R3和R4各自独立地表示氢原子或取代基; R1表示n价的部分结构，n表示大于或等于1的整数; 其中所述化合物包括每个分子中选自-NH-和-CO-的至少一个基团和至少一个选自-X 2 - （C = X 4）-X 3 - ， - NR 5 - （SO2） - ， - CO-NR6-CO-，-O - ， - S-，-COOH，-CN，-NR7R8，-OH和-SH。

公开(公告)号：US20160060405A1

公开(公告)日：2016-03-03

申请号：US14843723

申请日：2015-09-02

Applicant: FUJIFILM Corporation

Inventor： Yasukazu KUWAYAMA ,  Nobutaka FUKAGAWA ,  Hiroshi INADA ,  Masaki NORO ,  Yoshitaka MAEDA ,  Naozumi SHIRAIWA ,  Yu NAITO

IPC: C08J5/18 ,  G02B1/14 ,  G02B5/30 ,  G02F1/1335

CPC classification number: C08J5/18 ,  B32B2457/202 ,  C08J2301/12 ,  C08J2323/24 ,  C08J2333/12 ,  G02B5/3033 ,  G02F1/133528 ,  Y10T428/10 ,  Y10T428/1036

Abstract: The polymer film comprises a carbonyl bond-containing polymer and a compound having δh of equal to or higher than 11.0 and δχ of equal to or lower than 1.50, wherein the δh is a value of hydrogen-bonding capacity calculated by Hoy method and the δχ is a value calculated by equation 1: δχ=|x−13.3|  Equation 1 wherein, in equation 1, χ represents an interatomic distance in the polymer film between atoms most distant from each other among molecules in the compound, excluding a hydrogen atom, calculated by molecular dynamics calculation.

Abstract translation: 聚合物膜包含含羰基键的聚合物和δh等于或高于11.0且δx等于或低于1.50的化合物，其中δh是通过Hoy法计算的氢键合能力的值，δχ 是由等式1计算的值：δχ= | x-13.3 | 方程1其中，在等式1中，χ表示通过分子动力学计算计算的化合物中除了氢原子之外的分子之间彼此最远的原子之间的聚合物膜中的原子间距离。

公开(公告)号：US20220096381A1

公开(公告)日：2022-03-31

申请号：US17457793

申请日：2021-12-06

Applicant: FUJIFILM Corporation

Inventor： Taisuke ENDO ,  Shun KANEUMI ,  Masaki NORO ,  Shintaro TANABE ,  Masahiko YAMAMOTO

IPC: A61K9/127 ,  A61K31/7105 ,  A61K47/10 ,  A61K47/28 ,  A61K47/18 ,  A61K47/24

Abstract: An object of the present invention is to provide a lipid composition making it possible to achieve excellent delivery of nucleic acids. According to the present invention, there is provided a lipid composition containing a lipid represented by Formula (1) or a salt thereof, a nonionic lipid, a lipid having a nonionic hydrophilic polymer structure, and a nucleic acid, in which the lipid composition contains or does not contain a zwitterionic lipid, and in a case where (A) represents a molar ratio in percentage of the lipid represented by Formula (1) or a salt thereof to total lipids constituting the lipid composition and (B) represents a molar ratio in percentage of the zwitterionic lipid to total lipids constituting the lipid composition, (A) and (B) satisfy 40

公开(公告)号：US20160124123A1

公开(公告)日：2016-05-05

申请号：US14991544

申请日：2016-01-08

Applicant: FUJIFILM Corporation

Inventor： Masaki NORO ,  Yutaka NOZOE ,  Hiroshi INADA ,  Naoya SHIMOJU ,  Hisato NAGASE ,  Hiroyuki HAGIO ,  Yu NAITO ,  Nobutaka FUKAGAWA

IPC: G02B1/14 ,  G02F1/1335 ,  G02B5/30 ,  C08J5/18

CPC classification number: G02B1/14 ,  C08J5/18 ,  C08J2301/10 ,  C08K5/3462 ,  C08L1/10 ,  G02B5/3033 ,  G02B5/305 ,  G02F1/133528

Abstract: A cellulose acylate film, containing at least: a cellulose acylate; and a compound represented by the following Formula (I): wherein R1, R3 and R5 each independently designate a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, or an aromatic group, which groups may have a further substituent; with the proviso that at least one of R1, R3 and R5 is an alkyl group substituted with a group having a ring structure or a cycloalkyl group, and the total number of the ring structures existing in R1, R3 and R5 is 3 or more.

Abstract translation: 纤维素酰化物膜，至少含有：酰化纤维素; 和由下式（I）表示的化合物：其中R1，R3和R5各自独立地表示氢原子，烷基，环烷基，烯基或芳族基团，该基团可以具有另外的取代基; 条件是R 1，R 3和R 5中的至少一个是被具有环结构或环烷基的基团取代的烷基，并且存在于R 1，R 3和R 5中的环结构的总数为3以上。

公开(公告)号：US20130266744A1

公开(公告)日：2013-10-10

申请号：US13907357

申请日：2013-05-31

Applicant: FUJIFILM CORPORATION

Inventor： Aiko YAMAMOTO ,  Satoshi TANAKA ,  Teruki NIORI ,  Masato NAGURA ,  Masaki NORO ,  Aiko YOSHIDA ,  Nobutaka FUKAGAWA ,  Yasukazu KUWAYAMA

IPC: C08K5/3462 ,  G02B5/30

CPC classification number: C07D239/48 ,  C07D213/73 ,  C07D213/75 ,  C07D239/42 ,  C07D239/47 ,  C07D239/50 ,  C07D239/52 ,  C07D239/69 ,  C07D239/95 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C08K5/3432 ,  C08K5/3462 ,  G02B1/04 ,  G02B5/30 ,  G02B5/305 ,  G02B5/3083 ,  Y10T428/10 ,  Y10T428/1036 ,  Y10T428/1041 ,  C08L1/08

Abstract: Provided is a polymer film containing at least one of a compound represented by formula (1) of hydrates, solvates, or salts thereof. Y is a methine group or nitrogen atom. Qa, Qb, and Qc are a single bond or a divalent linking group. Ra, Rb, and Rc, are hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, cyano group, halogen group, or heterocyclic group. X2 is a single bond or a divalent linking group. X1 is a single bond or a predetermined divalent linking group. R1 and R2 are a hydrogen atom, alkyl group, alkenyl group, alkynyl group, aryl group, or heterocyclic group

Abstract translation: 提供含有水合物，溶剂合物或其盐的式（1）表示的化合物中的至少一种的聚合物膜。 Y是次甲基或氮原子。 Qa，Qb和Qc是单键或二价连接基团。 R a，R b和R c分别为氢原子，烷基，烯基，炔基，芳基，氰基，卤素基或杂环基。 X2是单键或二价连接基团。 X1是单键或预定的二价连接基团。 R1和R2是氢原子，烷基，烯基，炔基，芳基或杂环基

公开(公告)号：US20160187537A1

公开(公告)日：2016-06-30

申请号：US15008990

申请日：2016-01-28

Applicant: FUJIFILM Corporation

Inventor： Hiroyuki HAGIO ,  Shinichi ICHIKAWA ,  Masaki NORO ,  Yu NAITO ,  Nobutaka FUKAGAWA ,  Yutaka NOZOE

IPC: G02B1/04 ,  G02B5/30 ,  G02B1/14 ,  G02F1/1335

CPC classification number: G02B1/04 ,  G02B1/14 ,  G02B5/3033 ,  G02F1/133528 ,  Y10T428/105

Abstract: An optical film is provided containing cellulose acylate and at least one type of a compound denoted by the following Formula (I). R1 represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, a heterocyclic group, an acyl group, an alkoxy carbonyl group, a carbamoyl group, an alkyl sulfonyl group, or an aryl sulfonyl group, R2 represents an alkyl group or an aryl group, L represents a single bond or a bivalent or more connecting group, and n represents 1 when L is a single bond and n represents an integer of the valence of L−1 when L is a bivalent or more connecting group. s and t each independently represent 1 to 3, and X represents —O— or —N(Ra)-. Ra represents a hydrogen atom or an alkyl group.

Abstract translation: 提供含有纤维素酰化物和至少一种类型由下式（I）表示的化合物的光学膜。 R1表示氢原子，烷基，烯基，芳基，杂环基，酰基，烷氧基羰基，氨基甲酰基，烷基磺酰基或芳基磺酰基，R2表示烷基 基或芳基，L表示单键或2价以上的连接基，当L为单键时，n表示1，当L为2价以上连接基时，n表示L-1的化合价的整数 。 s和t各自独立地表示1〜3，X表示-O-或-N（Ra） - 。 R a表示氢原子或烷基。

公开(公告)号：US20160122486A1

公开(公告)日：2016-05-05

申请号：US14988171

申请日：2016-01-05

Applicant: FUJIFILM Corporation

Inventor： Masaki NORO ,  Hiroshi INADA ,  Yoshinori KANAZAWA ,  Aiko YOSHIDA ,  Yasukazu KUWAYAMA

IPC: C08J5/18 ,  G02F1/1335 ,  G02B5/30 ,  G02B1/14 ,  G02B1/04

CPC classification number: C08J5/18 ,  C08J2301/10 ,  C08K5/3462 ,  C08L1/10 ,  C08L1/12 ,  G02B1/04 ,  G02B1/14 ,  G02B5/3033 ,  G02B5/305 ,  G02F1/133528 ,  Y10T428/105

Abstract: The invention is an optical film at least containing cellulose acylate and a compound having a structure denoted by General Formula (I) described below, and a polarizing plate and a liquid crystal display device employing the optical film. R1 and R3 represent a hydrogen atom, an alkyl group, an alkenyl group, a cycloalkyl group, a cycloalkenyl group, or an aryl group, and R5a and R5b represent an alkyl group, an alkenyl group, a cycloalkyl group, a cycloalkenyl group, an aryl group, or a heterocyclic group. R1, R3, R5a, and R5b may have a substituent group.

Abstract translation: 本发明是至少含有纤维素酰化物和具有下述通式（I）表示的结构的化合物的光学膜和使用该光学膜的偏振片和液晶显示装置。 R1和R3表示氢原子，烷基，烯基，环烷基，环烯基或芳基，R5a和R5b表示烷基，烯基，环烷基，环烯基， 芳基或杂环基。 R1，R3，R5a和R5b可以具有取代基。