COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME

    公开(公告)号:US20230219932A1

    公开(公告)日:2023-07-13

    申请号:US18048426

    申请日:2022-10-20

    CPC classification number: C07D403/08 C07D471/04

    Abstract: There are provided a compound of Formula (1) and a labeled biological substance having the compound.





    Z1 and Z2 represent a specific 6-membered ring. However, at least one of Z1 or Z2 is a benzene ring having a specific substituent at an ortho position with respect to a nitrogen atom to which L1 or L2 is bonded, or a specific nitrogen-containing 6-membered ring in which a ring-constituting atom located at the ortho position is a nitrogen atom.
    R1 to R4, R11 to R13, L1, L2, and R21 represents specific groups, and n, α1, α2, and m represent specific numbers.
    The compound has at least one structure represented by —(CH2—CH2—O)m-R21 on a heterocyclic ring and has at least one substituent capable of being bonded to a carboxy group or a biological substance at a specific position, and in a case where at least one of Z1 or Z2 is the specific nitrogen-containing 6-membered ring, the specific substituents may be bonded to each other to form a ring.

    COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME

    公开(公告)号:US20220283170A1

    公开(公告)日:2022-09-08

    申请号:US17742378

    申请日:2022-05-11

    Abstract: Provided are any one of the following compounds and a fluorescently labeled biological substance having this compound. R1 to R27, L11, L12, and X+ represent a specific group, and at least one of R1 to R4 represents a substituted alkyl group.
    In a case where at least one of R1 to R4 is an alkyl group having a carboxy group or a substituent capable of being bonded to a biological substance, at least one of R11 to R27 is an alkyl group or an aryl group, or at least one of R1 to R4, which does not correspond to the alkyl group having a carboxy group or an alkyl group having a substituent capable of being bonded to a biological substance, is an alkyl group having a sulfoalkyl group through a single bond or a linking group.
    The total of n1 to n4 is an integer of 3 or more, and m=n1+n2+n3+n4−1 is satisfied.
    At least one of R1 to R4, R13, L11 or L12 in Formula (1) and at least one of R1 to R4, R24, L11, or L12 in Formula (2) have a specific substituent.

    PRODUCING METHOD OF PLASMA POLYMERIZED FILM AND LAMINATED FILM, IMAGE FORMING METHOD, AND PLASMA POLYMERIZED FILM
    5.
    发明申请
    PRODUCING METHOD OF PLASMA POLYMERIZED FILM AND LAMINATED FILM, IMAGE FORMING METHOD, AND PLASMA POLYMERIZED FILM 审中-公开
    等离子体聚合薄膜和层压薄膜的制备方法,成像方法和等离子体聚合薄膜

    公开(公告)号:US20140079939A1

    公开(公告)日:2014-03-20

    申请号:US14090717

    申请日:2013-11-26

    CPC classification number: C08F2/46 C08F2/38 C08F2/52 C09D11/30

    Abstract: A producing method of a plasma polymerized film includes irradiating a composition containing at least one kind of radically polymerizable compound, and at least one of a polymerization initiator and a chain transfer agent with plasma.The plasma polymerized film is formed by polymerizing a composition containing at least one of a polymerization initiator and a chain transfer agent, and at least one kind of radically polymerizable compound by irradiation of plasma.

    Abstract translation: 等离子体聚合膜的制造方法包括用等离子体照射含有至少一种自由基聚合性化合物和聚合引发剂和链转移剂中的至少一种的组合物。 等离子体聚合膜通过聚合包含聚合引发剂和链转移剂中的至少一种的组合物和通过等离子体照射的至少一种自由基聚合性化合物而形成。

    COMPOUND AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME

    公开(公告)号:US20230159547A1

    公开(公告)日:2023-05-25

    申请号:US18069982

    申请日:2022-12-21

    CPC classification number: C07D487/14

    Abstract: There are provided a compound of Formula (1) and a labeled biological substance having the compound.




    R1 to R6, R11 to R13, and R22 to R29 represent specific groups, and n is an integer of 1 to 3.
    One selected from R1, R2, R5, R22 to R25 and one selected from R3, R4, R6, and R26 to R29 are bonded through a linking group LL.
    The linking group LL represents a linking group having 1 to 100 atoms, which does not have any one of an aromatic hydrocarbon ring, a sulfo group, or a phosphono group.
    R1, . . . , R6, R22, . . . , or R29 includes a structure represented by —(CH2—CH2—O)m—, where m is 1 to 50.
    The above-described compound is a neutral compound and contains at least one substituent capable of being bonded to a carboxy group or a biological substance.

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