公开(公告)号：US20200299723A1

公开(公告)日：2020-09-24

申请号：US16897860

申请日：2020-06-10

Applicant: FUJIFILM Corporation

Inventor： Tatsuya MATSUURA ,  Tsukasa ISHIHARA

IPC: C12N15/85 ,  C12N5/071 ,  C12N15/87 ,  C12N9/02 ,  C07K16/00

Abstract: An object of the present invention is to provide an animal cell with improved proliferation ability and survival rate, a method for producing the animal cell, and a method for producing a target protein formed of the animal cell. According to the present invention, there is provided an animal cell having a gene encoding a target protein and a foreign gene encoding an isovaleryl-CoA dehydrogenase, in which the isovaleryl-CoA dehydrogenase is overexpressed.

公开(公告)号：US20210301262A1

公开(公告)日：2021-09-30

申请号：US17344590

申请日：2021-06-10

Applicant: FUJIFILM Corporation

Inventor： Yuya WATANABE ,  Tatsuya MATSUURA

IPC: C12N5/10 ,  C07K14/705 ,  C12N15/89

Abstract: Provided are an animal cell capable of producing a target protein with high productivity, a method for producing the animal cell, and a method for producing a target protein using the animal cell. According to an aspect of the present invention, there are provided an animal cell that has a gene encoding a target protein and a foreign gene encoding SNAT2 and linked to a promoter and overexpresses SNAT2; a method for producing the animal cell; and a method for producing a target protein using the animal cell.