KIT FOR PRODUCING ADENO-ASSOCIATED VIRUS, AND USE THEREOF

    公开(公告)号:US20240018547A1

    公开(公告)日:2024-01-18

    申请号:US18448499

    申请日:2023-08-11

    CPC classification number: C12N15/86 C12N7/02 C12N2750/14143

    Abstract: An object of the present invention is to provide a kit and an integration vector for preparing an adeno-associated virus-producing cell capable of controlled manufacture of an adeno-associated virus, and to provide an adeno-associated virus-producing cell capable of controlled manufacture of an adeno-associated virus, a manufacturing method of the same, and a manufacturing method of the adeno-associated virus. According to the present invention, a kit including a first vector containing one or more virus helper genes, in which at least one of the virus helper genes is under a control of a promoter capable of regulating expression, and a second vector containing one or more adeno-associated virus genes, in which at least one of the adeno-associated virus genes is not under a control of a promoter regulating expression is provided.

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