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1.发明申请COMPOSITIONS COMPRISING REDUCED GENOME BACTERIA FOR USE IN TREATMENT OF SEPSIS 审中-公开包含减少基因细菌的组合物用于治疗SEPSIS公开(公告)号：US20120093865A2
公开(公告)日：2012-04-19
申请号：US13148037
申请日：2010-02-10
IPC分类号： A61K39/02 , A61P31/04 , A61P37/04 , A61K39/108 , C12N1/20
CPC分类号： A61K35/74 , Y02A50/473
摘要： Methods for prophylaxis or treatment of sepsis in a subject are provided comprising administering to the subject a therapeutically effective dose of multiple deletion strain bacteria.
摘要翻译： 提供了用于预防或治疗受试者败血症的方法，包括向受试者施用治疗有效剂量的多种缺失菌株细菌。
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2.发明申请COMPOSITIONS COMPRISING REDUCED GENOME BACTERIA FOR USE IN TREATMENT OF SEPSIS 审中-公开包含减少基因细菌的组合物用于治疗SEPSIS公开(公告)号：US20110293662A1
公开(公告)日：2011-12-01
申请号：US13148037
申请日：2010-02-10
IPC分类号： A61K39/02 , A61P31/04 , A61P37/04 , A61K39/108 , C12N1/20
CPC分类号： A61K35/74 , Y02A50/473
摘要： Methods for prophylaxis or treatment of sepsis in a subject are provided comprising administering to the subject a therapeutically effective dose of multiple deletion strain bacteria.
摘要翻译： 提供了用于预防或治疗受试者败血症的方法，包括向受试者施用治疗有效剂量的多种缺失菌株细菌。
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公开(公告)号：US06855814B2
公开(公告)日：2005-02-15
申请号：US10114170
申请日：2002-04-01
IPC分类号： C07K14/245 , C12Q1/68 , C07H21/02
CPC分类号： C07K14/245
摘要： The entire genome of pathogenic E. coli strain 0157:H7 has been sequenced. All of the genomic DNA sequences present in 0157 and absent in the previously sequenced laboratory strain K12 are presented here.
摘要翻译： 病原性大肠杆菌菌株0157：H7的整个基因组已被测序。 存在于0157中的所有基因组DNA序列和在先前测序的实验室菌株K12中不存在。
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公开(公告)号：US06365723B1
公开(公告)日：2002-04-02
申请号：US09453702
申请日：1999-12-03
IPC分类号： C07H2102
CPC分类号： C07K14/245
摘要： The entire genome of pathogenic E. coli strain O157:H7 has been sequenced. All of the genomic DNA sequences present in O157 and absent in the previously sequenced laboratory strain K12 are presented here.
摘要翻译： 病原性大肠杆菌菌株O157：H7的整个基因组已被测序。 存在于O157中的所有基因组DNA序列和在先前测序的实验室菌株K12中不存在。
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公开(公告)号：US06706522B1
公开(公告)日：2004-03-16
申请号：US09409800
申请日：1999-09-30
申请人： Frederick R. Blattner , Valerie Burland , Debra J. Rose , George F. Mayhew , Nicole Perna , Robert D Perry , Susan C Straley , Jacqueline D. Fetherston , Luther E. Lindler , Gregory V. Plano
发明人： Frederick R. Blattner , Valerie Burland , Debra J. Rose , George F. Mayhew , Nicole Perna , Robert D Perry , Susan C Straley , Jacqueline D. Fetherston , Luther E. Lindler , Gregory V. Plano
IPC分类号： C12N1563
CPC分类号： C07K14/24
摘要： The complete DNA sequence of three plasmids from the bacterium Yersinia pestis, the causative agent for bubonic plague, have been determined and are set forth. The open reading frames, or protein coding regions, of the plasmids have been determined. The DNA sequence and ORF information is useful for the creation of diagnostic, prophylactic and therapeutic tools for combating the disease caused by this agent.
摘要翻译： 已经确定了来自鼠疫耶尔森氏菌（Yersinia pestis）的三种质粒的完整DNA序列，其是引起瘟疫的病原体。 已经确定了质粒的开放阅读框或蛋白质编码区。 DNA序列和ORF信息可用于创建用于对抗由该试剂引起的疾病的诊断，预防和治疗工具。
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