公开(公告)号：US20190184358A1

公开(公告)日：2019-06-20

申请号：US16328129

申请日：2017-09-04

Applicant: GE Healthcare BioProcess R&D AB

Inventor： Jimmy Hedin Dahlstrom ,  Jonas Bengtsson ,  Per Erik Emilsson ,  Maranda Fordham ,  Eva Holmgren ,  Ronnie Palmgren ,  Fernando Polanco

IPC: B01J2/06 ,  B01F3/08

CPC classification number: B01J2/06 ,  B01F3/0811 ,  B01F5/0696 ,  B01F2003/0834 ,  B01F2003/0842

Abstract: A system and method for producing fine droplets of polysaccharide from a premixed water-in-oil emulsion uses a packed bed (5) comprising hydrophilic beads (7).

公开(公告)号：US20180291184A1

公开(公告)日：2018-10-11

申请号：US15578074

申请日：2016-05-27

Applicant: GE HEALTHCARE BIOPROCESS R&D AB

Inventor： Per Erik Emilsson ,  Susanna Klara Margareta Lindberg ,  Jonny Wernersson ,  Jonas Afsson ,  Adam Hurynowicz

IPC: C08L5/02 ,  C08B37/02 ,  C12N5/00 ,  C07K1/22 ,  B01J13/14

Abstract: The invention discloses a method of manufacturing polysaccharide beads, comprising the steps of: i) providing a water phase comprising an aqueous solution of a polysaccharide; ii) providing an oil phase comprising at least one water-immiscible organic solvent and at least one oil-soluble emulsifier; iii) emulsifying the water phase in the oil phase to form a water-in-oil (w/o) emulsion; and iv) inducing solidification of the water phase in the w/o emulsion, wherein the organic solvent is an aliphatic or alicyclic ketone or ether.