Deep learning system for differential diagnosis of skin diseases

    公开(公告)号:US12040080B2

    公开(公告)日:2024-07-16

    申请号:US17620445

    申请日:2020-09-11

    Applicant: Google LLC

    CPC classification number: G16H30/40 G16H10/60 G16H50/20

    Abstract: The present disclosure is directed to a deep learning system for differential diagnoses of skin diseases. In particular, the system performs a method that can include obtaining a plurality of images that respectively depict a portion of a patient's skin. The method can include determining, using a machine-learned skin condition classification model, a plurality of embeddings respectively for the plurality of images. The method can include combining the plurality of embeddings to obtain a unified representation associated with the portion of the patient's skin. The method can include determining, using the machine-learned skin condition classification model, a skin condition classification for the portion of the patients skin, the skin condition classification produced by the machine-learned skin condition classification model by processing the unified representation, wherein the skin condition classification identifies one or more skin conditions selected from a plurality of potential skin conditions.

    Method and System for Assisting Pathologist Identification of Tumor Cells in Magnified Tissue Images

    公开(公告)号:US20200066407A1

    公开(公告)日:2020-02-27

    申请号:US16488029

    申请日:2017-02-23

    Applicant: Google LLC

    Abstract: A method, system and machine for assisting a pathologist in identifying the presence of tumor cells in lymph node tissue is disclosed. The digital image of lymph node tissue at a first magnification (e.g., 40×) is subdivided into a multitude of rectangular “patches.” A likelihood of malignancy score is then determined for each of the patches. The score is obtained by analyzing pixel data from the patch (e.g., pixel data centered on and including the patch) using a computer system programmed as an ensemble of deep neural network pattern recognizers, each operating on different magnification levels of the patch. A representation or “heatmap” of the slide is generated. Each of the patches is assigned a color or grayscale value in accordance with (1) the likelihood of malignancy score assigned to the patch by the combined outputs of the ensemble of deep neural network pattern recognizers and (2) a code which assigns distinct colors (or grayscale values) to different values of likelihood of malignancy scores assigned to the patches.

    Self Supervised Training of Machine-Learned Image Processing Models for Histopathology

    公开(公告)号:US20250117893A1

    公开(公告)日:2025-04-10

    申请号:US18908549

    申请日:2024-10-07

    Applicant: Google LLC

    Abstract: An example computer-implemented method for self-supervised training of an image processing model for histopathology images is provided. The example method includes obtaining a reference histopathology image; generating an augmented histopathology image, wherein generating the augmented histopathology image comprises performing, for an input image, at least one of the following augmentations: applying a blur to the input image and injecting noise artifacts into the blurred input image; or cropping a plurality of portions from the input image, wherein the plurality of portions are determined based on a minimum overlap criterion that has been updated over one or more iterations; and training the image processing model based on a similarity of latent representations generated by the image processing model respectively for the reference histopathology image and the augmented histopathology image.

    Method and system for assisting pathologist identification of tumor cells in magnified tissue images

    公开(公告)号:US11170897B2

    公开(公告)日:2021-11-09

    申请号:US16488029

    申请日:2017-02-23

    Applicant: Google LLC

    Abstract: A method, system and machine for assisting a pathologist in identifying the presence of tumor cells in lymph node tissue is disclosed. The digital image of lymph node tissue at a first magnification (e.g., 40×) is subdivided into a multitude of rectangular “patches.” A likelihood of malignancy score is then determined for each of the patches. The score is obtained by analyzing pixel data from the patch (e.g., pixel data centered on and including the patch) using a computer system programmed as an ensemble of deep neural network pattern recognizers, each operating on different magnification levels of the patch. A representation or “heatmap” of the slide is generated. Each of the patches is assigned a color or grayscale value in accordance with (1) the likelihood of malignancy score assigned to the patch by the combined outputs of the ensemble of deep neural network pattern recognizers and (2) a code which assigns distinct colors (or grayscale values) to different values of likelihood of malignancy scores assigned to the patches.

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