公开(公告)号：US20240350808A1

公开(公告)日：2024-10-24

申请号：US18685989

申请日：2022-08-26

Applicant: GALVANI BIOELECTRONICS LIMITED

Inventor： David Karl Lee PETERSON ,  Kevin KWONG ,  Gerald Edwin HUNSBERGER ,  Jason MIRANDA ,  Isha GUPTA ,  Paul MATTEUCCI ,  Daniel CHEW

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/08 ,  A61N1/375

CPC classification number: A61N1/3614 ,  A61N1/0556 ,  A61N1/36139 ,  A61N1/36142 ,  A61N1/36146 ,  A61N1/375 ,  A61N2001/083

Abstract: Systems for applying electrical stimulation to a nerve and determining a change in measured impedance or sensed electrical fields that is indicative of an electrical event, are disclosed herein. The system comprises an implantable housing comprising a signal generator, an implantable neural interface, an impedance measuring circuit or an electrical field sensing circuit, and processing circuitry. Methods for determining the presence of an electrical event in a system for applying electrical stimulation to a nerve, are also disclosed herein. The method comprises periodically sensing an impedance in an electrical pathway and determining an electrical event in the electrical pathway by identifying a change in the sensed impedance.

公开(公告)号：US20210178153A1

公开(公告)日：2021-06-17

申请号：US17248735

申请日：2021-02-05

Applicant: Galvani Bioelectronics Limited

Inventor： Faisal ZAIDI ,  Sabastien OUCHOUCHE ,  Paul MATTEUCCI

IPC: A61N1/05 ,  A61K9/00 ,  A61K31/56 ,  A61N1/36 ,  A61N1/375

Abstract: An extravascular or intravascular neural interface is disclosed comprising three C-ring portions, with at least two including an electrode, an electrode pair or an electrode array. The portions are formed of a flexible material that is configured to enable the portions to self-size to fit around or against a surface of a target vessel when the neural interface is released at a position along the target vessel. A spinal portion configured to house electrical conductors for the electrodes is connected to one or more portions. The portions may be spaced sufficient apart to permit radial expansion and contraction of a target vessel around or within which the neural interface is placed, to reduce never compression, open trench low-pressure unrestricted blood-flow, and to enhance fluid exchange with the target vessel. The portions may be arranged in a low helix angle forming at least two full turns.