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公开(公告)号:US20240092887A1
公开(公告)日:2024-03-21
申请号:US18364185
申请日:2023-08-02
Applicant: Genentech, Inc.
Inventor: Gerald R. NAKAMURA , Dhaya SESHASAYEE , Menno VAN LOOKEREN CAMPAGNE , Tiffany WONG , Jia WU , Hongkang XI , Jack BEVERS, III , Hiu Nam CHAN , Laetitia COMPS-AGRAR , Racquel CORPUZ
IPC: C07K16/24 , A61K39/395 , A61K45/06
CPC classification number: C07K16/244 , A61K39/3955 , A61K45/06 , A61K2039/505
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of making and using the same, e.g., for treatment of IL-33 mediated disorders (e.g., ocular disorders such as AMD (e.g., geographic atrophy (GA)).
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公开(公告)号:US20210301005A1
公开(公告)日:2021-09-30
申请号:US17205663
申请日:2021-03-18
Applicant: Genentech, Inc.
Inventor: Wei-Ching LIANG , Joseph R. ARRON , Daryle DEPIANTO , Wendy Green HALPERN , WeiYu LIN , Patrick J. LUPARDUS , Thirumalai Rajan RAMALINGAM , Dhaya SESHASAYEE , Tianhe SUN , Tulika TYAGI , Jia WU , Yan WU , Jian Ping YIN
Abstract: The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
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