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公开(公告)号:US20230279102A1
公开(公告)日:2023-09-07
申请号:US18062956
申请日:2022-12-07
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , C07K16/30 , A61K45/06 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/34 , C07K2317/56 , C07K2317/90 , C07K2317/94
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20220177551A1
公开(公告)日:2022-06-09
申请号:US17681665
申请日:2022-02-25
Applicant: Genentech, Inc.
Inventor: Meredith Carroll HAZEN , Zhonghua LIN , Dhaya SESHASAYEE
IPC: C07K16/00 , C12N5/0781
Abstract: The instant technology generally relates to improved methods for producing antibodies, antibody libraries, hybridomas, hybridoma libraries, etc. For example, these methods increase the number of antigen-specific B cells produced, increase the number of hybridomas, and/or increase the number of monoclonal antibodies that can be made in a given production cycle.
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公开(公告)号:US20240117037A1
公开(公告)日:2024-04-11
申请号:US18345587
申请日:2023-06-30
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K39/395 , A61K45/06 , C07K16/30
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20170088613A1
公开(公告)日:2017-03-30
申请号:US15274603
申请日:2016-09-23
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K45/06 , C07K16/30 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20240092887A1
公开(公告)日:2024-03-21
申请号:US18364185
申请日:2023-08-02
Applicant: Genentech, Inc.
Inventor: Gerald R. NAKAMURA , Dhaya SESHASAYEE , Menno VAN LOOKEREN CAMPAGNE , Tiffany WONG , Jia WU , Hongkang XI , Jack BEVERS, III , Hiu Nam CHAN , Laetitia COMPS-AGRAR , Racquel CORPUZ
IPC: C07K16/24 , A61K39/395 , A61K45/06
CPC classification number: C07K16/244 , A61K39/3955 , A61K45/06 , A61K2039/505
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of making and using the same, e.g., for treatment of IL-33 mediated disorders (e.g., ocular disorders such as AMD (e.g., geographic atrophy (GA)).
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公开(公告)号:US20220064286A1
公开(公告)日:2022-03-03
申请号:US17526338
申请日:2021-11-15
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210301005A1
公开(公告)日:2021-09-30
申请号:US17205663
申请日:2021-03-18
Applicant: Genentech, Inc.
Inventor: Wei-Ching LIANG , Joseph R. ARRON , Daryle DEPIANTO , Wendy Green HALPERN , WeiYu LIN , Patrick J. LUPARDUS , Thirumalai Rajan RAMALINGAM , Dhaya SESHASAYEE , Tianhe SUN , Tulika TYAGI , Jia WU , Yan WU , Jian Ping YIN
Abstract: The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
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公开(公告)号:US20210284725A1
公开(公告)日:2021-09-16
申请号:US17199810
申请日:2021-03-12
Applicant: Genentech, Inc.
Inventor: Gerald R. NAKAMURA , Dhaya SESHASAYEE , Menno VAN LOOKEREN CAMPAGNE , Tiffany WONG , Jiansheng WU , Hongkang XI , Jack BEVERS, III , Joyce CHAN , Laetitia COMPS-AGRAR , Racquel CORPUZ
IPC: C07K16/24 , A61K45/06 , A61K39/395
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of making and using the same, e.g., for treatment of IL-33 mediated disorders (e.g., ocular disorders such as AMD (e.g., geographic atrophy (GA)).
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公开(公告)号:US20210253693A1
公开(公告)日:2021-08-19
申请号:US17244682
申请日:2021-04-29
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210032328A1
公开(公告)日:2021-02-04
申请号:US17064464
申请日:2020-10-06
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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