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    Apparatus and method for the delivery of drugs and genes into tissue
    1.
    发明授权
    Apparatus and method for the delivery of drugs and genes into tissue 失效
    用于将药物和基因递送到组织中的装置和方法

    公开(公告)号：US06192270B1

    公开(公告)日：2001-02-20

    申请号：US09134245

    申请日：1998-08-14

    申请人： Gunter A. Hofmann ,  Dietmar Rabussay ,  Arnt Tonnessen

    发明人： Gunter A. Hofmann ,  Dietmar Rabussay ,  Arnt Tonnessen

    IPC分类号： A61N130

    CPC分类号： A61N1/0424 ,  A61N1/042 ,  A61N1/0436 ,  A61N1/044 ,  A61N1/30 ,  A61N1/325

    摘要： An electrode assembly for an apparatus for and a method of trans-surface molecular delivery, including a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a first electrode disposed on at least a portion of the distal surface and extending through at least a portion of the plurality of through holes and onto at least a portion of the proximal surface, a second electrode disposed on at least a portion of the proximal surface and in closely spaced relation with the first electrode for engaging a tissue surface through which to apply an electric field, and an insulating barrier that is disposed on at least a portion of the proximal surface of the carrier between the first electrode and the second electrode.

    摘要翻译： 一种用于反式表面分子传递的装置和方法的电极组件，包括具有近端表面，远端表面和从近端表面到远端表面的多个通孔的非导电载体，第一电极 设置在所述远端表面的至少一部分上并且延伸穿过所述多个通孔的至少一部分并且延伸到所述近端表面的至少一部分上，第二电极，设置在所述近端表面的至少一部分上并且紧密地 与用于接合施加电场的组织表面的第一电极间隔开的关系;以及设置在第一电极和第二电极之间的载体近端表面的至少一部分上的绝缘屏障。