公开(公告)号：US10898448B2

公开(公告)日：2021-01-26

申请号：US16604311

申请日：2018-04-19

申请人： HISAMITSU PHARMACEUTICAL CO., INC.

发明人： Takito Shima ,  Toshiyuki Matsudo ,  Kenji Ishigaki

IPC分类号： A61K9/70 ,  A61K31/485 ,  A61K47/22 ,  A61K47/32 ,  A61K47/34

摘要： A patch comprises a backing layer and an adhesive layer, wherein the adhesive layer contains at least one selected from the group consisting of butorphanol and pharmaceutically acceptable salts thereof, and contains an adhesive base and an antioxidant containing a sulfur atom in its molecule.

公开(公告)号：US11364207B2

公开(公告)日：2022-06-21

申请号：US16483511

申请日：2018-02-19

申请人： HISAMITSU PHARMACEUTICAL CO., INC.

发明人： Hideaki Ohashi ,  Takito Shima ,  Kenji Ishigaki ,  Yasunari Michinaka

IPC分类号： A61K9/70 ,  A61K31/4045 ,  A61K47/02

摘要： A patch comprising: a backing layer; and an adhesive layer, wherein the adhesive layer contains a mixture of a pharmaceutically acceptable acid addition salt of ropinirole and potassium hydrogen carbonate, and the mixture contains at least one selected from the group consisting of ropinirole and pharmaceutically acceptable acid addition salts thereof and potassium hydrogen carbonate.