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19 条记录 (耗时 0.036 秒)

    Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
    7.
    发明授权
    Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof 有权
    吡喃葡萄糖氧基苄基苯衍生物及其医药用途

    公开(公告)号：US07541341B2

    公开(公告)日：2009-06-02

    申请号：US10467823

    申请日：2002-02-13

    申请人： Nobuhiko Fushimi ,  Kazuya Tatani ,  Hideki Fujikura ,  Toshihiro Nishimura ,  Minoru Fujioka ,  Takeshi Nakabayashi ,  Masayuki Isaji

    发明人： Nobuhiko Fushimi ,  Kazuya Tatani ,  Hideki Fujikura ,  Toshihiro Nishimura ,  Minoru Fujioka ,  Takeshi Nakabayashi ,  Masayuki Isaji

    IPC分类号： A61K31/70 ,  C07H15/00 ,  C07H17/00

    CPC分类号： C07H15/203

    摘要： The present invention provides glucopyranosyloxybenzylbenzene derivatives represented by the general formula: wherein P represents a hydrogen atom or a group forming a prodrug; R1 represents a hydrogen atom, an optionally substituted amino group, a carbamoyl group, an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, etc.; R2 represents a hydrogen atom or a lower alkyl group; and R3 represents an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, an optionally substituted lower alkylthio group, etc., which have an improved oral absorption, and exert an inhibitory activity in human SGLT2, and therefore are useful as drugs for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, or pharmaceutically acceptable salts thereof, and pharmaceutical uses thereof.

    摘要翻译： 本发明提供由以下通式表示的吡喃葡萄糖氧基苄基苯衍生物：其中P表示氢原子或形成前药的基团; R1表示氢原子，任选取代的氨基，氨基甲酰基，任选取代的低级烷基，任选取代的低级烷氧基等; R2表示氢原子或低级烷基; R3代表任意取代的低级烷基，任意取代的低级烷氧基，任意取代的低级烷硫基等，它们具有改善的口服吸收，并且在人SGLT2中具有抑制活性，因此可用作 预防或治疗与糖尿病，糖尿病并发症或肥胖症等高血糖相关的疾病或其药学上可接受的盐及其药学用途。

    Diaphragm-type pressure sensing apparatus
    8.
    发明授权
    Diaphragm-type pressure sensing apparatus 有权
    隔膜式压力传感装置

    公开(公告)号：US07313970B2

    公开(公告)日：2008-01-01

    申请号：US11407399

    申请日：2006-04-19

    申请人： Toshihito Nonaka ,  Shingo Wanami ,  Minoru Fujioka

    发明人： Toshihito Nonaka ,  Shingo Wanami ,  Minoru Fujioka

    IPC分类号： G01L7/00

    CPC分类号： G01L19/141 ,  G01L19/148

    摘要： A diaphragm-type pressure sensing apparatus includes a pressure sensor having a diaphragm for converting pressure into an electrical signal, a circuit board for processing the electrical signal, and a housing in which the pressure sensor and the circuit board are sealed. The pressure sensor is bonded to the housing and sandwiched between the circuit board fixed to the housing and the housing. This structure reduces compressive stress applied to the pressure sensor and the circuit board so that accuracy of the pressure sensing apparatus can be improved.

    摘要翻译： 膜片式压力感测装置包括压力传感器，该压力传感器具有用于将压力转换为电信号的膜片，用于处理电信号的电路板，以及密封压力传感器和电路板的壳体。 压力传感器结合到壳体并夹在固定到壳体的电路板和壳体之间。 这种结构降低了施加到压力传感器和电路板的压缩应力，从而可以提高压力感测装置的精度。

    Air bag system
    9.
    发明授权
    Air bag system 失效
    气囊系统

    公开(公告)号：US06206409B1

    公开(公告)日：2001-03-27

    申请号：US09139761

    申请日：1998-08-25

    申请人： Hirokazu Kato ,  Tadashi Ozaki ,  Minoru Fujioka ,  Mutsumasa Koujiya

    发明人： Hirokazu Kato ,  Tadashi Ozaki ,  Minoru Fujioka ,  Mutsumasa Koujiya

    IPC分类号： B60R2126

    CPC分类号： B60R21/217 ,  B60R21/201 ,  B60R21/237 ,  B60R2021/161

    摘要： An air bag system comprises an air bag having an opening through which gas is supplied. The air bag is folded in a predetermined polygonal shape and is then contained in a pad. An expansion restraining member is provided in the air bag system. The expansion restraining member temporarily holds a peripheral portion of the folded air bag so as to suppress rapid expansion thereof when the air bag is developed. Because the expansion of the peripheral portion is delayed by the expansion restraining member, it is possible to prevent the air bag from developing in the straight thin form toward a passenger. That is, the air bag can be developed in a round shape from its center portion when the gas is supplied into the air bag.

    摘要翻译： 气囊系统包括具有供给气体的开口的气囊。 将气囊折叠成预定的多边形，然后将其包含在垫中。 在气囊系统中设置有膨胀限制构件。 膨胀限制构件临时保持折叠气囊的周边部分，以便在气囊展开时抑制其快速膨胀。 由于周边部的膨胀被膨胀限制构件延迟，因此可以防止气囊朝向乘客呈直线状的形状。 也就是说，当气体供应到气囊中时，气囊可以从其中心部分呈圆形显影。

    Side door collision detecting system and occupant protecting system
    10.
    发明授权
    Side door collision detecting system and occupant protecting system 失效
    侧门碰撞检测系统和乘员保护系统

    公开(公告)号：US07711467B2

    公开(公告)日：2010-05-04

    申请号：US11413144

    申请日：2006-04-27

    申请人： Toshihito Nonaka ,  Satoru Takehara ,  Minoru Fujioka

    发明人： Toshihito Nonaka ,  Satoru Takehara ,  Minoru Fujioka

    IPC分类号： B60R21/00 ,  B60T7/22

    CPC分类号： B60R21/0136 ,  B60R2021/0006 ,  B60R2021/0119

    摘要： In a side door collision detecting system for a vehicle, an internal pressure sensor detects a door internal pressure of a side door of the vehicle. The internal pressure sensor outputs an internal pressure signal based on the door internal pressure, and the internal pressure sensor is installed in an interior space of the side door. A physical value sensor detects a physical value and outputs a physical value signal based on the physical value. The physical value sensor is installed in the interior space of the side door. A collision determining circuit determines whether the side collision occurs based on the internal pressure signal and the physical value signal.

    摘要翻译： 在车辆的侧门碰撞检测系统中，内部压力传感器检测车辆的侧门的门内部压力。 内部压力传感器基于门内部压力输出内部压力信号，并且内部压力传感器安装在侧门的内部空间中。 物理值传感器检测物理值，并根据物理值输出物理值信号。 物理值传感器安装在侧门的内部空间中。 冲突判定电路基于内部压力信号和物理值信号来判定是否发生侧面碰撞。