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公开(公告)号:US20170106125A1
公开(公告)日:2017-04-20
申请号:US15294047
申请日:2016-10-14
Applicant: Industrial Technology Research Institute
Inventor: Yu-Chi WANG , Hsin-Hsin SHEN , Chin-Fu CHEN , Meng-Yow HSIEH , Sen-Lu CHEN , Yu-Bing LIOU , Tsai-Yu LIN , Pei-Shan LI , Wei-Lin YU
CPC classification number: A61L31/145 , A61L31/041 , A61L31/048 , A61L31/14 , A61L2400/06 , C08L29/04
Abstract: The present disclosure provides a hydrogel composition including: a hydrogel having a structure represented by Formula (I) or Formula (II) shown as follows: A-B-BOX-B-A, Formula (I); B-A-B-(BOX-BAB)n-BOX-B-A-B, Formula (II), wherein, A is a hydrophilic polyethylene glycol polymer, B is a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2′-Bis(2-oxazoline) for coupling di-block of A-B or tri-block of B-A-B, and n is an integer greater than or equal to 0; and an anti-adhesion additive, wherein the anti-adhesion additive comprises a carbohydrate, a nitrogen-containing cyclic compound, a polymer or a combination thereof.