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    Allergenic proteins and peptides from dog dander and uses therefor
    1.
    发明授权
    Allergenic proteins and peptides from dog dander and uses therefor 失效
    来自狗皮屑的过敏性蛋白质和肽类及其用途

    公开(公告)号：US06489118B2

    公开(公告)日：2002-12-03

    申请号：US09374671

    申请日：1999-08-16

    申请人： Jay P. Morgenstern ,  Christine B. Bizinkauskas ,  Andrzej Konieczny ,  Andrew W. Brauer

    发明人： Jay P. Morgenstern ,  Christine B. Bizinkauskas ,  Andrzej Konieczny ,  Andrew W. Brauer

    IPC分类号： G01N3353

    CPC分类号： G01N33/6893 ,  A61K38/00 ,  A61K39/00 ,  C07K14/46 ,  C07K14/47 ,  G01N2800/24

    摘要： Isolated nucleic acids encoding allergens of Canis familiaris, Canf I or Can f II, are disclosed. A cDNA encoding a peptide having a Can f I activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can f II activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can f I or Can f II nucleic acid in a sample or for the recombinant production of petides having a Can f I or Can f II activity. Peptides having a Can f I or Can f II activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.

    摘要翻译： 公开了编码Canis familiaris，Canf I或Can f II的过敏原的分离的核酸。 还描述了编码具有Can f I活性和约19,200道尔顿的预测分子量的肽的cDNA。 还公开了编码具有Can f II活性和预测分子量约18,200道尔顿的肽的cDNA。 核酸可以用作探针以检测样品中Can f I或Can f II核酸的存在，或用于重组生产具有Can f I或Can f II活性的化合物。 具有Can f I或Can f II活性的肽可用于适用于药物施用的组合物或诊断对狗皮的敏感性的方法。

    Allergenic proteins and peptides from dog dander and uses therefor
    3.
    发明授权
    Allergenic proteins and peptides from dog dander and uses therefor 失效
    来自狗皮屑的过敏性蛋白质和肽类及其用途

    公开(公告)号：US07166291B2

    公开(公告)日：2007-01-23

    申请号：US11202960

    申请日：2005-08-12

    申请人： Jay P. Morgenstern ,  Christine B. Bizinkauskas ,  Andrzej Konieczny ,  Andrew W. Brauer

    发明人： Jay P. Morgenstern ,  Christine B. Bizinkauskas ,  Andrzej Konieczny ,  Andrew W. Brauer

    IPC分类号： A61K39/35 ,  A61K39/00 ,  C07K14/00 ,  C12P21/06 ,  C07H21/04

    CPC分类号： G01N33/6893 ,  A61K38/00 ,  A61K39/00 ,  C07K14/46 ,  C07K14/47 ,  G01N2800/24

    摘要： Isolated nucleic acids encoding allergens of Canis familiaris, Can fI or Can fII. are disclosed. A cDNA encoding a peptide having a Can fI activity and a predicted molecular weight of about 19,200 daltons is also described. A cDNA encoding a peptide having Can fII activity and a predicted molecular weight of about 18,200 daltons is also disclosed. The nucleic acids can be used as probes to detect the presence of Can fI or Can fII nucleic acid in a sample or for the recombinant production of petides having a Can fI or Can fII activity. Peptides having a Can fI or Can fII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to dog dander.

    摘要翻译： 编码Canis familiaris，Can fI或Can fII的过敏原的分离核酸。 被披露。 还描述了编码具有Can fI活性和约19,200道尔顿的预测分子量的肽的cDNA。 还公开了编码具有Can fII活性和预测分子量约18,200道尔顿的肽的cDNA。 核酸可以用作探针，以检测样品中Can fI或Can fII核酸的存在，或用于重组生产具有Can fI或Can fII活性的化合物。 具有Can fI或Can fII活性的肽可用于适合于药物施用的组合物或诊断对狗皮的敏感性的方法。