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公开(公告)号：US20060051364A1
公开(公告)日：2006-03-09
申请号：US10533811
申请日：2003-10-29
申请人： Jesus Valenzuela , Jose Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
发明人： Jesus Valenzuela , Jose Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
IPC分类号： A61K39/02
CPC分类号： A61K39/008 , A61K38/00 , A61K39/0003 , A61K2039/53 , A61K2039/57 , A61K2039/575 , A61K2039/58 , C07K14/43577 , C07K14/44 , C07K16/18 , C07K16/20 , C07K2317/21 , C12N15/63 , Y02A50/41
摘要： Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
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公开(公告)号：US07485306B2
公开(公告)日：2009-02-03
申请号：US10533811
申请日：2003-10-29
申请人： Jesus G Valenzuela , Jose M. C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
发明人： Jesus G Valenzuela , Jose M. C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
CPC分类号： A61K39/008 , A61K38/00 , A61K39/0003 , A61K2039/53 , A61K2039/57 , A61K2039/575 , A61K2039/58 , C07K14/43577 , C07K14/44 , C07K16/18 , C07K16/20 , C07K2317/21 , C12N15/63 , Y02A50/41
摘要： Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
摘要翻译： 基本纯化唾液Lu。 长双歧杆菌多肽和编码这些多肽的多核苷酸。 载体和宿主细胞包括Lu。 长披龙多核苷酸也被公开。 在一个实施方案中，公开了用于诱导对沙蝇唾液的免疫应答的方法。 在其他实施方案中，公开了治疗，诊断或预防利什曼病的方法。
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公开(公告)号：US08628780B2
公开(公告)日：2014-01-14
申请号：US12350179
申请日：2009-01-07
申请人： Jesus G. Valenzuela , Jose M. C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
发明人： Jesus G. Valenzuela , Jose M. C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
CPC分类号： A61K39/008 , A61K38/00 , A61K39/0003 , A61K2039/53 , A61K2039/57 , A61K2039/575 , A61K2039/58 , C07K14/43577 , C07K14/44 , C07K16/18 , C07K16/20 , C07K2317/21 , C12N15/63 , Y02A50/41
摘要： Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
摘要翻译： 基本纯化唾液Lu。 长双歧杆菌多肽和编码这些多肽的多核苷酸。 载体和宿主细胞包括Lu。 长披龙多核苷酸也被公开。 在一个实施方案中，公开了用于诱导对沙蝇唾液的免疫应答的方法。 在其他实施方案中，公开了治疗，诊断或预防利什曼病的方法。
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公开(公告)号：US20090117139A1
公开(公告)日：2009-05-07
申请号：US12350179
申请日：2009-01-07
申请人： Jesus G. Valenzuela , Jose M.C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
发明人： Jesus G. Valenzuela , Jose M.C. Ribeiro , Aldina Barral , Manoel Netto , Claudia Brodskyn , Regis Gomes
IPC分类号： A61K39/00 , A61K31/7088 , A61K38/17 , C40B30/04 , A61P33/02
CPC分类号： A61K39/008 , A61K38/00 , A61K39/0003 , A61K2039/53 , A61K2039/57 , A61K2039/575 , A61K2039/58 , C07K14/43577 , C07K14/44 , C07K16/18 , C07K16/20 , C07K2317/21 , C12N15/63 , Y02A50/41
摘要： Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
摘要翻译： 基本纯化唾液Lu。 长双歧杆菌多肽和编码这些多肽的多核苷酸。 载体和宿主细胞包括Lu。 长披龙多核苷酸也被公开。 在一个实施方案中，公开了用于诱导对沙蝇唾液的免疫应答的方法。 在其他实施方案中，公开了治疗，诊断或预防利什曼病的方法。
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