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1.
公开(公告)号:US20100029002A1
公开(公告)日:2010-02-04
申请号:US12443492
申请日:2007-10-12
IPC分类号: C12N15/02
CPC分类号: C12N5/163 , C12N2500/90 , C12N2506/00
摘要: The present invention provides methods of enhancing hybridoma fusion efficiencies through cell synchronization of the fusion partners, in order to aid in production of antibodies.
摘要翻译: 本发明提供通过融合配偶体的细胞同步来增强杂交瘤融合效率的方法,以帮助抗体的产生。
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公开(公告)号:US20050221432A1
公开(公告)日:2005-10-06
申请号:US11095893
申请日:2005-03-31
CPC分类号: C07K14/47 , C07K16/00 , C07K16/2839 , C07K2317/21 , C12P21/00
摘要: Methods for altering the cellular secretion rate of a protein, such as an antibody and the altered cells produced by the method are disclosed. The methods and altered cells are useful for producing high levels of proteins for therapeutic, diagnostic or research purposes.
摘要翻译: 公开了改变蛋白质如抗体和通过该方法产生的改变的细胞的细胞分泌速率的方法。 方法和改变的细胞可用于产生用于治疗,诊断或研究目的的高水平蛋白质。
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3.
公开(公告)号:US08216842B2
公开(公告)日:2012-07-10
申请号:US12443492
申请日:2007-10-12
IPC分类号: C12N15/06 , C12N5/078 , C12N5/0781 , C12N5/16 , C12N5/20
CPC分类号: C12N5/163 , C12N2500/90 , C12N2506/00
摘要: The present invention provides methods of enhancing hybridoma fusion efficiencies through cell synchronization of the fusion partners, in order to aid in production of antibodies.
摘要翻译: 本发明提供通过融合配偶体的细胞同步来增强杂交瘤融合效率的方法,以帮助抗体的产生。
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公开(公告)号:US07479379B2
公开(公告)日:2009-01-20
申请号:US11095893
申请日:2005-03-31
CPC分类号: C07K14/47 , C07K16/00 , C07K16/2839 , C07K2317/21 , C12P21/00
摘要: Methods for altering the cellular secretion rate of a protein, such as an antibody and the altered cells produced by the method are disclosed. The methods and altered cells are useful for producing high levels of proteins for therapeutic, diagnostic or research purposes.
摘要翻译: 公开了改变蛋白质如抗体和通过该方法产生的改变的细胞的细胞分泌速率的方法。 方法和改变的细胞可用于产生用于治疗,诊断或研究目的的高水平蛋白质。
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