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    Process for the production of perbenzylated 1-O-glycosides
    1.
    发明授权
    Process for the production of perbenzylated 1-O-glycosides 失效
    过苄基化1-O-糖苷的生产方法

    公开(公告)号：US06908989B2

    公开(公告)日：2005-06-21

    申请号：US10174508

    申请日：2002-06-19

    申请人： Johannes Platzek ,  Ulrich Niedballa ,  Klaus-Dieter Graske

    发明人： Johannes Platzek ,  Ulrich Niedballa ,  Klaus-Dieter Graske

    IPC分类号： C07H15/203 ,  C07H1/00

    CPC分类号： C07H15/203

    摘要： The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof in which sugar1 is a monosaccharide that is functionalized in 1-OH-position, R represents benzyl, n means 2, 3 or 4, X means —COO— or —NH— and L means a straight-chain, branched, saturated or unsaturated C1-C30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of perbenzylated saccharides with 1-O-functionalized side chains on an industrial scale.

    摘要翻译： 本发明涉及制备通式I的过苄氧基化的1-O-糖苷或其盐，其中糖1是在1-OH位官能化的单糖，R代表苄基 ，n表示2,3或4，X表示-COO-或-NH-，L表示直链，支链，饱和或不饱和的C 1 -C 30烷基， 碳链，其任选地被中断或被基团取代。 根据本发明的方法从经济起始材料开始，提供良好的产率并且允许以工业规模生产具有1-O-官能化侧链的过苄基化糖。

    Process for the production of peracylated 1-0-glycosides
    2.
    发明授权
    Process for the production of peracylated 1-0-glycosides 失效
    过氧化1-0-糖苷的生产方法

    公开(公告)号：US06831164B2

    公开(公告)日：2004-12-14

    申请号：US10192856

    申请日：2002-07-11

    申请人： Johannes Platzek ,  Klaus-Dieter Graske ,  Ulrich Niedballa

    发明人： Johannes Platzek ,  Klaus-Dieter Graske ,  Ulrich Niedballa

    IPC分类号： C07H1500

    CPC分类号： C07H15/18 ,  C07H15/04 ,  C07H15/26

    摘要： The invention relates to a process for the production of peracylated 1-O-glycosides of general formula I or salts thereof in which sugar1 is a monosaccharide that is functionalized in 1-OH-position, R represents methyl, ethyl, propyl, isopropyl, tbutyl, phenyl, n means 2, 3 or 4, X means —COO— or —NH—and L means a straight-chain, branched, saturated or unsaturated C1-C30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of peracylated saccharides with 1-O-functionalized side chains on an enlarged scale.

    摘要翻译： 本发明涉及一种制备通式I的过酰基化的1-O-糖苷或其盐的方法，其中1是在1-OH位官能化的单糖，R代表甲基，乙基，丙基，异丙基， 叔丁基，苯基，n表示2,3或4，X表示-COO-或-NH-，并且L表示直链，支链，饱和或不饱和的C1-C30碳链，其任选被中间或被基团取代。 根据本发明从经济起始材料开始，提供良好的产率并且允许以1-O官能化的侧链扩大生产过酰基化糖。