公开(公告)号：US11231778B2

公开(公告)日：2022-01-25

申请号：US16902040

申请日：2020-06-15

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunseon Seo ,  Inchan Youn ,  Hyojin Lee ,  Kang-Il Song ,  Donghee Son

IPC: H05K1/18 ,  G06F3/01 ,  C08K3/08 ,  C08G77/388 ,  H05K1/02 ,  H05K1/09 ,  H05K3/14 ,  H05K3/28 ,  H05K1/11

Abstract: A bidirectional self-healing neural interface includes a first elastic substrate; a neural electrode disposed on the first elastic substrate and comprising a conductive polymer composite; and a second elastic substrate disposed on the neural electrode. The conductive polymer composite includes a matrix formed of a self-healing polymer material; and a plurality of electrical conductor clusters distributed in the matrix. Each of the electrical conductor clusters includes particles of a first electrical conductor; and a plurality of particles of a second electrical conductor formed of the same material as that of the first electrical conductor, distributed around each of the particles of the first electrical conductor, and having sizes that are smaller than those of the particles of the first electrical conductor. The first electrical conductor is a source for generating the second electrical conductor. The neural interface has excellent elasticity, electrical conductivity that is improved by deformation, and is self-healing.

公开(公告)号：US12049564B2

公开(公告)日：2024-07-30

申请号：US16855547

申请日：2020-04-22

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Youngdo Jeong ,  Kwan Hyi Lee ,  Hyojin Lee

IPC: C08L79/04 ,  A61K9/51 ,  C08G73/06 ,  C08K3/105 ,  B82Y5/00 ,  B82Y30/00 ,  B82Y40/00

CPC classification number: C08L79/04 ,  A61K9/5146 ,  C08G73/06 ,  B82Y5/00 ,  B82Y30/00 ,  B82Y40/00 ,  C08K3/105

Abstract: Provided are positively charged nanoparticles and use thereof. According to the nanoparticles of an aspect, cucurbituril may limit electrostatic attraction between a guest for cucurbituril and a metal salt, thereby generating nanoparticles with a uniform size. Accordingly, the nanoparticles may have an effect of being capable of efficient intracellular gene delivery.