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1.
公开(公告)号:US08685983B2
公开(公告)日:2014-04-01
申请号:US13308310
申请日:2011-11-30
Applicant: Tae-Seong Kim , David Bauer , Steven Bellon , Alessadro Boezio , Shon Booker , Deborah Choquette , Derin C. D'Amico , Noel D'Angelo , Celia Dominguez , Ingrid M. Fellows , Julie Germain , Russell Graceffa , Jean-Christophe Harmange , Satoko Hirai , Daniel La , Matthew Lee , Longbin Liu , Mark H. Norman , Michele Potashman , Philip Roveto , Aaron C. Siegmund , Ning Xi , Kevin Yang
Inventor: Tae-Seong Kim , David Bauer , Steven Bellon , Alessadro Boezio , Shon Booker , Deborah Choquette , Derin C. D'Amico , Noel D'Angelo , Celia Dominguez , Ingrid M. Fellows , Julie Germain , Russell Graceffa , Jean-Christophe Harmange , Satoko Hirai , Daniel La , Matthew Lee , Longbin Liu , Mark H. Norman , Michele Potashman , Philip Roveto , Aaron C. Siegmund , Ning Xi , Kevin Yang
IPC: A61K31/497 , A61K31/5377 , A61K31/437 , A61K31/519 , A61K31/4184 , A61K31/501 , A61K31/4709 , A61K31/4365
CPC classification number: C07D413/12 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物,类似物,前药和药学上可接受的盐,用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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公开(公告)号:US20130033862A1
公开(公告)日:2013-02-07
申请号:US13196470
申请日:2011-08-02
Applicant: Kevin Yang
Inventor: Kevin Yang
CPC classification number: F21V23/026 , F21Y2103/00
Abstract: An external ballast fixture includes a top panel plate having sidewalls, lamp sockets connected to the top panel plate and lamps mounted to the lamp sockets. The sidewalls enclose the lamps. A ballast panel opening is formed on the top panel. The ballast panel opening has a ballast panel opening left side and a ballast panel opening right side. A ballast panel has a concave area. The ballast panel has a ballast panel left edge and the ballast panel has a ballast panel right edge. The ballast panel left edge connects to the fixture top panel at a ballast panel opening left side.
Abstract translation: 外部镇流器夹具包括具有侧壁的顶板,连接到顶板的灯插座和安装到灯插座的灯。 侧壁包围灯。 在顶板上形成一个镇流器板开口。 镇流器面板开口具有左侧的镇流器面板和右侧的镇流器面板。 镇流器面板具有凹面积。 镇流器面板的边缘为镇流器面板,镇流器面板为右侧边缘。 镇流器面板左边缘在镇流器开口左侧连接到固定装置顶板。
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公开(公告)号:US20120107275A1
公开(公告)日:2012-05-03
申请号:US13323692
申请日:2011-12-12
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/5025 , A61K31/5377 , C07D498/04 , A61K31/538 , A61K38/21 , A61P31/00 , A61P3/00 , A61P5/00 , A61P37/00 , C07D487/04 , A61P35/00
CPC classification number: C07D471/04 , C07D487/04 , C07D493/04 , C07D495/04 , C07D498/04 , C07D519/00
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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4.
公开(公告)号:US20120070413A1
公开(公告)日:2012-03-22
申请号:US13308310
申请日:2011-11-30
Applicant: Tae-Seong KIM , David Bauer , Steven Bellon , Alessadro Boezio , Shon Booker , Deborah Choquette , Derin C. D'Amico , Noel D'Angelo , Celia Dominguez , Ingrid M. Fellows , Julie Germain , Russell Graceffa , Jean-Christophe Harmange , Satoko Hirai , Daniel La , Matthew Lee , Longbin Liu , Mark H. Norman , Michele Potashman , Philip Roveto , Aaron C. Siegmund , Ning Xi , Kevin Yang
Inventor: Tae-Seong KIM , David Bauer , Steven Bellon , Alessadro Boezio , Shon Booker , Deborah Choquette , Derin C. D'Amico , Noel D'Angelo , Celia Dominguez , Ingrid M. Fellows , Julie Germain , Russell Graceffa , Jean-Christophe Harmange , Satoko Hirai , Daniel La , Matthew Lee , Longbin Liu , Mark H. Norman , Michele Potashman , Philip Roveto , Aaron C. Siegmund , Ning Xi , Kevin Yang
IPC: A61K38/21 , A61K31/497 , A61K31/5377 , A61P35/00 , A61K31/437 , A61K31/519 , A61K31/4184 , A61K31/501 , A61K31/4709 , A61K31/4365
CPC classification number: C07D413/12 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物,类似物,前药和药学上可接受的盐,用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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5.
公开(公告)号:US07928140B2
公开(公告)日:2011-04-19
申请号:US12221416
申请日:2008-08-01
Applicant: Shon Booker , Noel D'Angelo , Derin C. D'Amico , Tae-Seong Kim , Longbin Liu , Kristin Meagher , Mark H. Norman , Kathleen Panter , Laurie B. Schenkel , Adrian L. Smith , Nuria A. Tamayo , Douglas A. Whittington , Ning Xi , Kevin Yang
Inventor: Shon Booker , Noel D'Angelo , Derin C. D'Amico , Tae-Seong Kim , Longbin Liu , Kristin Meagher , Mark H. Norman , Kathleen Panter , Laurie B. Schenkel , Adrian L. Smith , Nuria A. Tamayo , Douglas A. Whittington , Ning Xi , Kevin Yang
IPC: A61K31/38
CPC classification number: C07D277/82 , C07D413/04 , C07D417/04 , C07D417/14 , C07D513/04
Abstract: The present invention comprises a new class of compounds capable of modulating the activity of PI3 kinase and, accordingly, useful for treatment of PI3 kinase mediated diseases, including melanomas, carcinomas and other cancer-related conditions. The compounds have a general Formula I wherein each of A1, A2, A3, A4, X, R1 and R2 are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of PI3 kinase mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
Abstract translation: 本发明包括能够调节PI3激酶活性的新一类化合物,因此可用于治疗PI3激酶介导的疾病,包括黑素瘤,癌和其它癌症相关病症。 所述化合物具有通式I,其中A1,A2,A3,A4,X,R1和R2各自在本文中定义。 本发明还包括药物组合物,治疗PI3激酶介导的疾病的方法,以及可用于制备本发明化合物的中间体和方法。
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公开(公告)号:US07852580B2
公开(公告)日:2010-12-14
申请号:US12078592
申请日:2008-04-02
Applicant: Kevin Yang
Inventor: Kevin Yang
IPC: G02B7/02
Abstract: An actuation device having a shape memory alloy component containing: a base having a bottom portion, at least one first magnetic component disposed under the bottom portion of base, a carrier having a top portion, at least one second magnetic component which is disposed on the top portion of carrier and which corresponds in location to the first magnetic component, and a shape memory alloy component which is disposed between the base and the carrier. Shape memory alloy component has at least one deformable supporting component, which is disposed at a position corresponding to both positions of the first magnetic component and of the second magnetic component, for supporting the carrier. The supporting component is in a horizontal form between the base and the carrier since there is a magnetic force between the first magnetic component and the second magnetic component.
Abstract translation: 一种具有形状记忆合金部件的致动装置,包括:具有底部的基部,设置在基部的底部下方的至少一个第一磁性部件,具有顶部的载体,至少一个第二磁性部件, 载体的顶部并且其位置对应于第一磁性部件,以及形状记忆合金部件,其设置在基部和载体之间。 形状记忆合金部件具有至少一个可变形支撑部件,该可变形支撑部件设置在对应于第一磁性部件和第二磁性部件的两个位置的位置,用于支撑载体。 由于在第一磁性部件和第二磁性部件之间存在磁力,所以支撑部件在底部和载体之间呈水平形式。
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公开(公告)号:US20090318436A1
公开(公告)日:2009-12-24
申请号:US12287791
申请日:2008-10-14
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michelle Potashman , Aaron C. Siegmund , Stephanie K. Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michelle Potashman , Aaron C. Siegmund , Stephanie K. Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/5355 , C07D487/02 , A61K31/5025 , C07D413/14 , C07D471/02 , A61K31/437 , A61K31/53 , C07D498/02 , A61K31/4355 , A61P35/00
CPC classification number: C07D471/04 , C07D487/04 , C07D493/04 , C07D495/04 , C07D498/04 , C07D519/00
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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公开(公告)号:US20090296404A1
公开(公告)日:2009-12-03
申请号:US12387362
申请日:2009-05-01
Applicant: Kevin Yang
Inventor: Kevin Yang
IPC: F21V7/00
CPC classification number: F21V23/026
Abstract: A universal mount lighting fixture comprises a housing having a rectangular profile with a ballast channel disposed in a top surface of the housing. The ballast channel extends across the length of the housing. A pair of ballast wire openings are disposed on a surface of the housing. A reflector is mounted within the housing. A ballast is mounted to an exterior surface of the housing. The ballast has two opposite edgewise basins with access openings for power wires to input and output connectors. The ballast can be mounted within the ballast channel and the pair of ballast wire openings can be disposed in a horizontal portion of the ballast channel. The channel can be flared. The ballast can be mounted on an end or side of the housing.
Abstract translation: 通用安装照明灯具包括具有矩形轮廓的壳体,其具有设置在壳体的顶表面中的压载通道。 镇流器通道延伸穿过壳体的长度。 一对镇流器丝线开口设置在壳体的表面上。 反射器安装在壳体内。 镇流器安装到外壳的外表面。 镇流器具有两个相对的沿边盆,其具有用于输入和输出连接器的电力线的进入开口。 镇流器可以安装在镇流器通道内,并且一对镇流器线路开口可以设置在镇流器通道的水平部分中。 通道可以发光。 镇流器可以安装在外壳的端部或侧面。
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公开(公告)号:US20090143355A1
公开(公告)日:2009-06-04
申请号:US12322361
申请日:2009-01-29
Applicant: Chester Chenguang Yuan , Kevin Yang , Simon Van Der Plas , Babak Riahi , Michele Potashman , Vinod F. Patel , Rana Nomak , Aiwen Li , Qi Huang , Jean-Christophe Harmange , Benny C. Askew, JR.
Inventor: Chester Chenguang Yuan , Kevin Yang , Simon Van Der Plas , Babak Riahi , Michele Potashman , Vinod F. Patel , Rana Nomak , Aiwen Li , Qi Huang , Jean-Christophe Harmange , Benny C. Askew, JR.
IPC: A61K31/517 , C07D401/02 , A61P35/00 , C07D413/14 , A61K31/4725 , A61K31/496 , C07D401/14
CPC classification number: C07D401/12 , C07D217/02 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds of Formula I and II wherein R, R1 and R2 for each formula are defined herein. The invention further includes analogs, prodrugs and pharmaceutically acceptable salts and derivatives of Formulas I and II, as well as pharmaceutical compositions, medicaments and methods thereof for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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公开(公告)号:US20090124612A1
公开(公告)日:2009-05-14
申请号:US11879034
申请日:2007-07-13
Applicant: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
Inventor: Brian K. Albrecht , David Bauer , Steven Bellon , Christiane M. Bode , Shon Booker , Alessandro Boezio , Deborah Choquette , Derin D'Amico , Jean-Christophe Harmange , Satoko Hirai , Randall W. Hungate , Tae-Seong Kim , Richard T. Lewis , Longbin Liu , Julia Lohman , Mark H. Norman , Michele Potashman , Aaron C. Siegmund , Stephanie Springer , Markian Stec , Ning Xi , Kevin Yang
IPC: A61K31/5377 , C07D487/04 , C07D471/04 , A61P35/04 , A61K31/437 , A61K31/5025
CPC classification number: C07D471/04
Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Abstract translation: 所选化合物对于预防和治疗诸如HGF介导的疾病等疾病是有效的。 本发明包括新颖的化合物,类似物,前药和药学上可接受的盐,用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。
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