公开(公告)号：US11371839B2

公开(公告)日：2022-06-28

申请号：US16307640

申请日：2018-11-02

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Hoon Sohn ,  Soonkyu Hwang ,  Jiho Park

IPC: G01B21/08 ,  G06T5/00 ,  G06T7/00

Abstract: A method of performing visualized measurement on thickness distribution of a paint film and an apparatus therefor. A measurement target region is heated by a heating unit that applies a light beam while moving relative to the measurement target region of a measurement target structure. A sensing unit moving together with the heating unit generates a plurality of thermal images related to a phenomenon in which thermal energy is propagated in the measurement target region by scanning and photographing the heated measurement target region. The thermal images in a dynamic state are converted into time-spatial-integrated thermal images in a static state by performing coordinate transformation according to a time-spatial-integrated coordinate transformation algorithm. A thickness of the paint film is calculated by using a Fourier thermal conduction equation. A noise caused by an external heat source is removed by subtracting a pre-heating time-spatial-integrated thermal image from the converted time-spatial-integrated thermal image.

公开(公告)号：US12046167B2

公开(公告)日：2024-07-23

申请号：US16512990

申请日：2019-07-16

Applicant: Samsung Display Co., Ltd. ,  Korea Advanced Institute of Science and Technology

Inventor： Hoon Sohn ,  Sangwoo Choi ,  Minsang Koo ,  Sanghyuk Kwon ,  Eunchul Shin ,  Woojin Jung ,  Jiho Park ,  Soonkyu Hwang

IPC: G01N25/72 ,  G01N21/17 ,  G01N21/95 ,  G01N21/956 ,  G09G3/00

CPC classification number: G09G3/006 ,  G01N21/171 ,  G01N21/95607 ,  G01N25/72 ,  G01N2021/95615

Abstract: An apparatus for inspecting a display panel for defects includes a table which supports the display panel, a laser excitation unit that irradiates a non-display area of the display panel with a point laser beam, a thermal wave detecting unit that generates thermal wave images of irradiated portions of the non-display area, a driving unit, and a control unit. A groove corresponding to an edge of the display panel may be defined in a top surface of the table. A defect, such as a crack, may be detected by comparing a defect pattern obtained from the thermal wave images with a pre-registered defect pattern.

公开(公告)号：US20210223037A1

公开(公告)日：2021-07-22

申请号：US16307640

申请日：2018-11-02

Applicant: Korea Advanced Institute of Science and Technology

Inventor： Hoon Sohn ,  Soonkyu Hwang ,  Jiho Park

IPC: G01B21/08 ,  G06T7/00 ,  G06T5/00

Abstract: A method of performing visualized measurement on thickness distribution of a paint film and an apparatus therefor. A measurement target region is heated by a heating unit that applies a light beam while moving relative to the measurement target region of a measurement target structure. A sensing unit moving together with the heating unit generates a plurality of thermal images related to a phenomenon in which thermal energy is propagated in the measurement target region by scanning and photographing the heated measurement target region. The thermal images in a dynamic state are converted into time-spatial-integrated thermal images in a static state by performing coordinate transformation according to a time-spatial-integrated coordinate transformation algorithm. A thickness of the paint film is calculated by using a Fourier thermal conduction equation. A noise caused by an external heat source is removed by subtracting a pre-heating time-spatial-integrated thermal image from the converted time-spatial-integrated thermal image.

公开(公告)号：US20150148428A1

公开(公告)日：2015-05-28

申请号：US14315943

申请日：2014-06-26

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Chulhee Choi ,  Kyuha Chong ,  Jiho Park

IPC: A61K47/24 ,  A61K9/107 ,  A61K31/122

CPC classification number: A61K47/24 ,  A61K9/1075 ,  A61K31/122

Abstract: Disclosed herein are a nanopreparation having a micelle structure for diagnosis or treatment of cancer diseases, and a method of preparing the same, and more particularly, a nanopreparation having a micelle structure available for diagonosis or treatment of cancer diseases and a method for preparing the same, wherein the nanopreparation is prepared by encapsulating a photosensitizer by forming micelle with polymeric lipid DSPE-mPEG. The nanopreparation having the micelle structure according to the present invention has a size of 12 nm or less by encapsulating hypericin, which is a photosensitizer, by forming micelle with polymeric lipid DSPE-mPEG having a molecular weight of 1500 to 2500. Resultingly, the nanopreparation easily overcomes a blood-tumor barrier (BTB) and an interstitial fluid pressure and has light induced cytotoxicity efficiency that is about more than 2.5 times higher than that of the case where hypericin is used alone.

Abstract translation: 本文公开了具有用于诊断或治疗癌症疾病的胶束结构的纳米制剂及其制备方法，更具体地，涉及具有可用于治疗癌症疾病的胶束结构的纳米制剂及其制备方法 其中通过用聚合脂质DSPE-mPEG形成胶束来包封光敏剂来制备纳米制备。 具有根据本发明的胶束结构的纳米制备通过用分子量为1500至2500的聚合脂质DSPE-mPEG形成胶束，通过包封金丝桃素（其是光敏剂）具有12nm或更小的尺寸。因此，纳米制备 容易克服血液肿瘤屏障（BTB）和间质液压力，并且具有比单独使用金丝桃素的情况高2.5倍以上的光诱导细胞毒性效应。

公开(公告)号：US09393308B2

公开(公告)日：2016-07-19

申请号：US14315943

申请日：2014-06-26

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Chulhee Choi ,  Kyuha Chong ,  Jiho Park

IPC: A61K47/24 ,  A61K31/122 ,  A61K9/107

CPC classification number: A61K47/24 ,  A61K9/1075 ,  A61K31/122

Abstract: Disclosed herein are a nanopreparation having a micelle structure for diagnosis or treatment of cancer diseases, and a method of preparing the same, and more particularly, a nanopreparation having a micelle structure available for diagonosis or treatment of cancer diseases and a method for preparing the same, wherein the nanopreparation is prepared by encapsulating a photosensitizer by forming micelle with polymeric lipid DSPE-mPEG. The nanopreparation having the micelle structure according to the present invention has a size of 12 nm or less by encapsulating hypericin, which is a photosensitizer, by forming micelle with polymeric lipid DSPE-mPEG having a molecular weight of 1500 to 2500. Resultingly, the nanopreparation easily overcomes a blood-tumor barrier (BTB) and an interstitial fluid pressure and has light induced cytotoxicity efficiency that is about more than 2.5 times higher than that of the case where hypericin is used alone.

Abstract translation: 本文公开了具有用于诊断或治疗癌症疾病的胶束结构的纳米制剂及其制备方法，更具体地，涉及具有可用于治疗癌症疾病的胶束结构的纳米制剂及其制备方法 其中通过用聚合脂质DSPE-mPEG形成胶束来包封光敏剂来制备纳米制备。 具有根据本发明的胶束结构的纳米制备通过用分子量为1500至2500的聚合脂质DSPE-mPEG形成胶束，通过包封金丝桃素（其是光敏剂）具有12nm或更小的尺寸。因此，纳米制备 容易克服血液肿瘤屏障（BTB）和间质液压力，并且具有比单独使用金丝桃素的情况高2.5倍以上的光诱导细胞毒性效应。