公开(公告)号：US20180018422A1

公开(公告)日：2018-01-18

申请号：US15667236

申请日：2017-08-02

Applicant: Life Technologies Corporation

Inventor： Robert LAGACE ,  Chien-Wei Chang ,  Lori Hennessy

IPC: G06F19/14 ,  G06F19/18

CPC classification number: G16B10/00 ,  G16B20/00

Abstract: Systems and methods for calculating a predictive index of identity of a nucleic acid sample using polymorphic genetic marker data are provided. In one embodiment, a predictive index of identity of the nucleic acid sample is calculated using a value from a second set of data from a polymorphic genetic marker that is not linked to a polymorphic genetic marker used to produce a first set of data. In another embodiment, the predictive index of identity is calculated using a value from a second set of data from a polymorphic genetic marker that is linked to a polymorphic genetic marker used to produce the first set of data. Systems and methods for generating an identifier for a biological sample and for verifying a relationship between a biological sample and an identifier are also provided. The identifier is an encoding of a set of values for polymorphic genetic markers.

公开(公告)号：US09518302B2

公开(公告)日：2016-12-13

申请号：US14739722

申请日：2015-06-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chien-Wei Chang ,  Lori Hennessy ,  Dennis Wang

IPC: C12P19/34 ,  C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2527/125

Abstract: The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification.

公开(公告)号：US09057110B2

公开(公告)日：2015-06-16

申请号：US13914478

申请日：2013-06-10

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chien-Wei Chang ,  Lori Hennessy ,  Dennis Wang

IPC: C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2527/125

Abstract: The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification.

Abstract translation: 本教导涉及用于扩增核酸的改进的方法，试剂盒和反应混合物。 在一些实施方案中，提供了新的直接缓冲液制剂，其允许以最少的样品纯化直接扩增粗样品中的核酸。