公开(公告)号：US20190170684A1

公开(公告)日：2019-06-06

申请号：US16265806

申请日：2019-02-01

Applicant: Life Technologies Corporation

Inventor： David DENNY ,  David WOO ,  Manjula ALIMINATI ,  Siva Kumar SAMSANI ,  Stephanie SCHNEIDER ,  Yoke Peng LIM ,  Sylvia CHANG

IPC: G01N27/447 ,  G16B30/00

CPC classification number: G01N27/44717 ,  G16B30/00

Abstract: In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.

公开(公告)号：US20180104790A1

公开(公告)日：2018-04-19

申请号：US15652425

申请日：2017-07-18

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yerramalli Subramaniam ,  Puneet SURI ,  Sylvia CHANG ,  Chengyong YANG

IPC: B24B41/06 ,  B24B5/04

CPC classification number: B24B41/062 ,  B24B5/04 ,  B24B41/065 ,  G05B11/01 ,  G16B30/00

Abstract: Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.