公开(公告)号：US20160342734A1

公开(公告)日：2016-11-24

申请号：US15159717

申请日：2016-05-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Francis T. Cheng ,  Chengyong Yang ,  Casey McFarland ,  Ying Wang

IPC: G06F19/22 ,  G01N21/64 ,  C12Q1/68 ,  G01N25/04

CPC classification number: G06F19/22 ,  C12Q1/6816 ,  C12Q1/6827 ,  G01N21/6428 ,  G01N25/04 ,  G01N2021/6439 ,  G06F19/24 ,  C12Q2527/107 ,  C12Q2537/165

Abstract: The present application provides for various embodiments of methods for the analysis of high resolution melt (HRM) curve data; where statistical assay variations in melt curve data may result from system noise in an analysis system. Such system noise may arise from various sources, such as the thermal non-uniformity of a thermocycler block in a thermal cycler apparatus, a detection system, etc. Additionally, various methods for the analysis of HRM curve data may provide an identification of a sample without the need for a user inputted information.

公开(公告)号：US10318705B2

公开(公告)日：2019-06-11

申请号：US15159717

申请日：2016-05-19

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Francis T. Cheng ,  Chengyong Yang ,  Casey McFarland ,  Ying Wang

IPC: G01N21/64 ,  G01N25/04 ,  C12Q1/6816 ,  C12Q1/6827 ,  G06F19/22 ,  G06F19/24

Abstract: The present application provides for various embodiments of methods for the analysis of high resolution melt (HRM) curve data; where statistical assay variations in melt curve data may result from system noise in an analysis system. Such system noise may arise from various sources, such as the thermal non-uniformity of a thermocycler block in a thermal cycler apparatus, a detection system, etc. Additionally, various methods for the analysis of HRM curve data may provide an identification of a sample without the need for a user inputted information.