专利检索 ap:("Lynn Bonham" OR "Baoqing Gong" OR "Robert E Finney" OR "David M Hollenback" OR "J Peter Klein" OR "David W Leung" OR "Scott A Shaffer" OR "Norina M Tang" OR "John Tulinsky" OR "Thayer H White") AND inv:"Lynn Bonham" 第 1 页

1.

发明授权
LPAAT-β inhibitors and uses thereof 失效
标题翻译： LPAAT-β抑制剂及其用途

公开(公告)号：US07608620B2

公开(公告)日：2009-10-27

申请号：US11601513

申请日：2006-11-16

申请人： Lynn Bonham , Baoqing Gong , Robert E Finney , David M Hollenback , J Peter Klein , David W Leung , Scott A Shaffer , Norina M Tang , John Tulinsky , Thayer H White

发明人： Lynn Bonham , Baoqing Gong , Robert E Finney , David M Hollenback , J Peter Klein , David W Leung , Scott A Shaffer , Norina M Tang , John Tulinsky , Thayer H White

IPC分类号： C07D251/52 , C07D251/38 , A61K31/53 , A61P35/00

CPC分类号： C07D251/70 , C07D251/50 , C07D251/52 , C07D251/54 , C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

摘要翻译： 本发明涉及三嗪及其用于抑制溶血磷脂酰基转移酶β（LPAAT-β）活性的用途。本发明还涉及使用所述三嗪治疗癌症的方法。本发明还涉及用于筛选LPAAT-β活性的方法。

2.

发明授权
LPAAT-β inhibitors and uses thereof 失效

公开(公告)号：US07064125B2

公开(公告)日：2006-06-20

申请号：US10712900

申请日：2003-11-13

申请人： Baoqing Gong , John Tulinsky , Lynn Bonham , J. Peter Klein , Robert E. Finney , David M. Hollenback , Scott A. Shaffer , Norina M. Tang , Thayer H. White , David W. Leung

发明人： Baoqing Gong , John Tulinsky , Lynn Bonham , J. Peter Klein , Robert E. Finney , David M. Hollenback , Scott A. Shaffer , Norina M. Tang , Thayer H. White , David W. Leung

IPC分类号： A01N43/66

CPC分类号： C07D251/70 , C07D251/50 , C07D251/52 , C07D251/54 , C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

3.

发明授权
LPAAT-β inhibitors and uses thereof 失效

公开(公告)号：US07199238B2

公开(公告)日：2007-04-03

申请号：US11224340

申请日：2005-09-12

申请人： Lynn Bonham , Baoqing Gong , Robert E Finney , David M Hollenback , J. Peter Klein , David W Leung , Scott A Shaffer , Norina M Tang , John Tulinsky , Thayer H White

发明人： Lynn Bonham , Baoqing Gong , Robert E Finney , David M Hollenback , J. Peter Klein , David W Leung , Scott A Shaffer , Norina M Tang , John Tulinsky , Thayer H White

IPC分类号： C07D251/52 , C07D251/38 , A61K31/53 , A61P35/00

CPC分类号： C07D251/70 , C07D251/50 , C07D251/52 , C07D251/54 , C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

4.

发明申请
LPAAT-beta inhibitors and uses thereof 失效
标题翻译： LPAAT-β抑制剂及其用途

公开(公告)号：US20070072856A1

公开(公告)日：2007-03-29

申请号：US11601513

申请日：2006-11-16

申请人： Baoqing Gong , John Tulinsky , Lynn Bonham , J. Klein , Robert Finney , David Hollenback , Scott Shaffer , Norina Tang , Thayer White , David Leung

发明人： Baoqing Gong , John Tulinsky , Lynn Bonham , J. Klein , Robert Finney , David Hollenback , Scott Shaffer , Norina Tang , Thayer White , David Leung

IPC分类号： A61K31/5377 , A61K31/53 , C07D413/02 , C07D251/48

CPC分类号： C07D251/70 , C07D251/50 , C07D251/52 , C07D251/54 , C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

摘要翻译： 本发明涉及三嗪及其用于抑制溶血磷脂酰基转移酶β（LPAAT-β）活性的用途。本发明还涉及使用所述三嗪治疗癌症的方法。本发明还涉及用于筛选LPAAT-β活性的方法。

5.

发明申请
LPAAT-beta inhibitors and uses thereof 失效
标题翻译： LPAAT-β抑制剂及其用途

公开(公告)号：US20060035896A1

公开(公告)日：2006-02-16

申请号：US11224340

申请日：2005-09-12

申请人： Lynn Bonham , J. Klein , Robert Finney , David Hollenback , Scott Shaffer , Norina Tang , Thayer White , David Leung , Baoqing Gong , John Tulinsky

发明人： Lynn Bonham , J. Klein , Robert Finney , David Hollenback , Scott Shaffer , Norina Tang , Thayer White , David Leung , Baoqing Gong , John Tulinsky

IPC分类号： A61K31/5377 , A61K31/53 , C07D413/02 , C07D403/02

CPC分类号： C07D251/70 , C07D251/50 , C07D251/52 , C07D251/54 , C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPMT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

摘要翻译： 本发明涉及三嗪及其用于抑制溶血磷脂酰基转移酶β（LPMT-β）活性的用途。本发明还涉及使用所述三嗪治疗癌症的方法。本发明还涉及用于筛选LPAAT-β活性的方法。

6.

发明授权
Mus dunni endogenous retroviral packaging cell lines 失效
标题翻译：鼻咽内源性逆转录病毒包装细胞系

公开(公告)号：US06136598A

公开(公告)日：2000-10-24

申请号：US075272

申请日：1998-05-08

申请人： A. Dusty Miller , Greg Wolgamot , Lynn Bonham

发明人： A. Dusty Miller , Greg Wolgamot , Lynn Bonham

IPC分类号： C07K14/15 , C12N5/10

CPC分类号： C12N7/00 , C07K14/005 , C12N2740/10022 , C12N2740/10052

摘要： Retroviral packaging cells produce replication-defective retroviral particles capable of binding to Mus dunni endogenous virus retroviral receptors on target cells and are useful in gene transfer and gene therapy. The packaging cell employs a vector encoding a M. dunni retroviral Env protein and produces the retroviral particles at high titer.

摘要翻译： 逆转录病毒包装细胞产生复制缺陷型逆转录病毒颗粒，其能够靶向靶细胞上的Mus dunni内源性病毒逆转录病毒受体，并且可用于基因转移和基因治疗。包装细胞采用编码M. i逆转录病毒Env蛋白的载体，并产生高滴度的逆转录病毒颗粒。