公开(公告)号：US07064125B2

公开(公告)日：2006-06-20

申请号：US10712900

申请日：2003-11-13

申请人： Baoqing Gong ,  John Tulinsky ,  Lynn Bonham ,  J. Peter Klein ,  Robert E. Finney ,  David M. Hollenback ,  Scott A. Shaffer ,  Norina M. Tang ,  Thayer H. White ,  David W. Leung

发明人： Baoqing Gong ,  John Tulinsky ,  Lynn Bonham ,  J. Peter Klein ,  Robert E. Finney ,  David M. Hollenback ,  Scott A. Shaffer ,  Norina M. Tang ,  Thayer H. White ,  David W. Leung

IPC分类号： A01N43/66

CPC分类号： C07D251/70 ,  C07D251/50 ,  C07D251/52 ,  C07D251/54 ,  C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

公开(公告)号：US20100189726A1

公开(公告)日：2010-07-29

申请号：US12569639

申请日：2009-09-29

申请人： Lynn BONHAM ,  J. Peter Klein ,  Robert E. Finney ,  David M. Hollenback ,  Scott A. Shaffer ,  Norina M. Tang ,  Thayer H. White ,  David W. Leung ,  Baoqing Gong ,  John Tulinsky

发明人： Lynn BONHAM ,  J. Peter Klein ,  Robert E. Finney ,  David M. Hollenback ,  Scott A. Shaffer ,  Norina M. Tang ,  Thayer H. White ,  David W. Leung ,  Baoqing Gong ,  John Tulinsky

IPC分类号： A61K31/53 ,  C07D251/50 ,  C07D405/12 ,  C07D251/52 ,  A61K39/00 ,  A61P35/00

CPC分类号： C07D251/70 ,  C07D251/50 ,  C07D251/52 ,  C07D251/54 ,  C07D251/58

摘要： The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-β activity.

摘要翻译： 本发明涉及三嗪及其用于抑制溶血磷脂酰基转移酶的用途。 （LPAAT-＆bgr）活动。 本发明还涉及使用所述三嗪治疗癌症的方法。 本发明还涉及用于筛选LPAAT-＆bgr的方法; 活动。

公开(公告)号：US4929197A

公开(公告)日：1990-05-29

申请号：US357832

申请日：1989-05-30

申请人： Robert E. Finney

发明人： Robert E. Finney

IPC分类号： H01R13/11 ,  H01R13/02 ,  H01R13/502 ,  H01R43/00 ,  H01R43/20

CPC分类号： H01R24/22 ,  H01R2107/00 ,  H01R43/16 ,  H01R43/20

摘要： A connector is provided which enables close spacing of socket contacts in a highly reliable manner. The connector includes contact assemblies that each have at least two sheet metal contacts (26, 28 in FIG. 2) lying in parallel planes and a dielectric support (54) molded to the rearward portions of the contacts and to wire conductors (50, 52) connected thereto. The dielectic support includes a spacer portion (56) with a pair of arms (60, 62) separating the forward or mating ends of the socket contacts. The spacer arms are initially molded so they diverge from living hinges (66, 68) connecting them to the rearward portion of the support, the arms being pivotal together and having latches that hold them together at positions between the contacts. One of the arms includes a projection or retainer (106) that holds the contact assembly in a connector frame.