公开(公告)号：US20230255684A1

公开(公告)日：2023-08-17

申请号：US18160277

申请日：2023-01-26

Applicant: Medtronic, Inc.

Inventor： Megan M. Schmidt ,  Daniel C. Sigg ,  Lars M. Mattison ,  Tomaz Jarm ,  Jernej Stublar ,  Damijan Miklavcic ,  Nicolas Coulombe

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2018/00577

Abstract: Evaluating a cardiac lesion formed by an ablation procedure, by receiving, by processing circuitry and following conclusion of delivery of ablation energy, a bioelectrical signal from an electrode proximate to a target location of cardiac tissue for the cardiac lesion; determining, by the processing circuitry, one or more characteristics of the received bioelectrical signal in a frequency band of the received bioelectrical signal; and estimating, by the processing circuitry, an efficacy of the cardiac lesion based on a comparison of the determined amplitude of the bioelectrical signal and a threshold amplitude.

公开(公告)号：US20220313355A1

公开(公告)日：2022-10-06

申请号：US17807827

申请日：2022-06-20

Applicant: Medtronic, Inc.

Inventor： Brian T. Howard ,  Mark T. Stewart ,  Damijan Miklavcic ,  Bushan K. Purushothaman ,  Jeremy M. Stimack

IPC: A61B18/14 ,  A61B5/287 ,  A61B34/20 ,  A61B5/00

Abstract: Methods, systems, and devices for enhancing the efficiency and efficacy of energy delivery and tissue mapping. One system includes a treatment element having a plurality of electrodes and an energy generator that is configured to deliver electric energy pulses to the electrodes in a variety of patterns. For example, electrodes may be arranged in closely spaced pairs. The energy generator may deliver mapping energy to each electrode in each pair individually to map tissue and may deliver ablation energy to the electrodes in each pair together, such that each pair is treated like a single electrode, to deliver ablation energy, such as bipolar ablation energy between adjacent pairs. One system includes at least one concave electrode, the configuration of which concentrates the energy and drives it deeper into the tissue. One system includes neutral electrodes between active electrodes, the energy generator selectively coupling the neutral electrodes to alter the ablation pattern.

公开(公告)号：US20240016540A1

公开(公告)日：2024-01-18

申请号：US18338046

申请日：2023-06-20

Applicant: MEDTRONIC, INC

Inventor： Daniel C. Sigg ,  Lars M. Mattison ,  Damijan Miklavcic

IPC: A61B18/14 ,  A61B5/00

CPC classification number: A61B18/1492 ,  A61B5/0006 ,  A61B2018/00577

Abstract: Methods of and systems for ablating cardiac tissue is disclosed. One example method includes monitoring an electrical signal of a heart of a patient. The electrical signal represents the heart beating. The method further includes determining, with an electronic processor and based on the electrical signal, an end-diastolic time period at an end of a diastolic time period during which diastole of the heart has occurred during a previous cardiac cycle. The method further includes determining, with the electronic processor and based on the electrical signal, that another cardiac cycle has begun. The method further includes causing, with the electronic processor, an electrode to deliver pulsed field ablation (PFA) energy to the heart during at least a portion of a time in which the end-diastolic time period of the another cardiac cycle is expected to occur.

公开(公告)号：US20230310061A1

公开(公告)日：2023-10-05

申请号：US18295416

申请日：2023-04-04

Applicant: Medtronic, Inc.

Inventor： Mark T. Stewart ,  Lars M. Mattison ,  Brian T. Howard ,  Damijan Miklavcic ,  Tadej Kotnik ,  Janja Dermol-Cerne ,  Tina Batista Napotnik

IPC: A61B18/12

CPC classification number: A61B18/1206 ,  A61B2017/00176

Abstract: A method of delivering pulsed electric field energy to perform ablation of a tissue includes providing a pulse train to an electrode. The pulse train may include a first set of pulses with a first pulse width to generate first electric field and a second set of pulses with a second pulse width greater than the first pulse width to generate a second electric field. The electrode may be positioned at a same position during generation of the first electric field and the second electric field. The first electric field may be configured to have a higher electroporation effect on the first elongated cells having a first orientation than on second elongated cells having a second orientation. The second electric field may be configured to have a higher electroporation effect on the second cells than on the first cells.