公开(公告)号：US20220273353A1

公开(公告)日：2022-09-01

申请号：US17678102

申请日：2022-02-23

Applicant: Medtronic, Inc.

Inventor： Brian T. Howard ,  Megan M. Schmidt ,  Lars M. Mattison

IPC: A61B18/12 ,  A61B18/16 ,  A61B18/14

Abstract: A method and a medical device for determining efficacy of a pulsed electric field (PEF) ablation procedure are disclosed. According to one aspect, the method includes generating at least one pulsed electric field (PEF) pulse to be delivered to at least one electrode of a plurality of electrodes, the at least one electrode being at a distal end of a PEF ablation catheter and being positionable in proximity to a target region of tissue to be ablated. The method also includes determining an index of completeness indicative of a completeness of ablation of the target region of tissue based at least in part on a change in a parameter compared to an expected change in the parameter, the change in the parameter being caused at least in part on an extent of ablation of the target region.

公开(公告)号：US20220175268A1

公开(公告)日：2022-06-09

申请号：US17540548

申请日：2021-12-02

Applicant: Medtronic, Inc.

Inventor： Megan M. Schmidt ,  Lars M. Mattison ,  Anthony Rorvick ,  Christina M. Crassas

IPC: A61B5/06 ,  A61B5/00 ,  A61B5/318

Abstract: A lesion characterization process is disclosed. According to one aspect, a method includes obtaining measurements of at least one of an impedance magnitude, impedance phase, a temperature, and electrical properties of tissue of the lesion. The method further includes determining at least one lesion property including at least one of a depth of the lesion, percent transmurality of the lesion, lesion surface area and lesion volume based on at least one of the obtained measurements.

公开(公告)号：US20230414275A1

公开(公告)日：2023-12-28

申请号：US18332953

申请日：2023-06-12

Applicant: Medtronic, Inc.

Inventor： Brian T. Howard ,  Megan M. Schmidt ,  Lars M. Mattison

IPC: A61B18/14 ,  A61B5/00 ,  A61B18/12

CPC classification number: A61B18/1492 ,  A61B5/4848 ,  A61B18/1206 ,  A61B2018/00791

Abstract: A medical system includes a generator configured to generate pulsed electric field (PEF) energy. A medical device is in electrical communication with the generator and has a plurality of electrodes configured to deliver the PEF energy to a target tissue to create electroporated regions in the target tissue. A delivery element tracking system is in communication with the generator and the medical device. The tracking system has processing circuitry configured to: measure a position of at least one of the plurality of electrodes prior to delivery of PEF energy to the target tissue with respect to the target tissue and correlate a PEF field distribution based on the delivery of PEF energy to the target tissue to determine or modify at least one metric of a therapeutic effect from the PEF delivery at positions other than the measured location of the plurality of electrodes.

公开(公告)号：US20230355301A1

公开(公告)日：2023-11-09

申请号：US18298731

申请日：2023-04-11

Applicant: Medtronic, Inc.

Inventor： Mary A. Beckman ,  Heather L. O'Connell ,  Timothy G. Laske ,  Mark T. Stewart ,  Brian T. Howard ,  Lars M. Mattison ,  Megan M. Schmidt ,  Sarah E. Ahlberg

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2018/00577

Abstract: An example system for use in ablating target tissue includes memory configured to store anatomical and/or physiological information of a patient and processing circuitry communicatively coupled to the memory. The processing circuitry is configured to, based on the anatomical information and/or the physiological information, determine ablation parameters, the ablation parameters including a suggested positioning of at least energy delivery element of at least one catheter and/or an amount of energy to be delivered via the at least one energy delivery element to the target tissue during ablation. The processing circuitry is configured to output, for display, a representation of at least one of a suggested positioning of the at least one energy delivery element during the ablation, a representation of the target tissue, or a representation of the predicted tissue volume that will be ablated after delivery of ablation energy.

公开(公告)号：US20230255684A1

公开(公告)日：2023-08-17

申请号：US18160277

申请日：2023-01-26

Applicant: Medtronic, Inc.

Inventor： Megan M. Schmidt ,  Daniel C. Sigg ,  Lars M. Mattison ,  Tomaz Jarm ,  Jernej Stublar ,  Damijan Miklavcic ,  Nicolas Coulombe

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2018/00577

Abstract: Evaluating a cardiac lesion formed by an ablation procedure, by receiving, by processing circuitry and following conclusion of delivery of ablation energy, a bioelectrical signal from an electrode proximate to a target location of cardiac tissue for the cardiac lesion; determining, by the processing circuitry, one or more characteristics of the received bioelectrical signal in a frequency band of the received bioelectrical signal; and estimating, by the processing circuitry, an efficacy of the cardiac lesion based on a comparison of the determined amplitude of the bioelectrical signal and a threshold amplitude.