公开(公告)号：US11278397B2

公开(公告)日：2022-03-22

申请号：US16403769

申请日：2019-05-06

Applicant: Medtronic, Inc.

Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

公开(公告)号：US09872766B2

公开(公告)日：2018-01-23

申请号：US14974996

申请日：2015-12-18

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10T29/49405

Abstract: A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration.

公开(公告)号：US20170224511A1

公开(公告)日：2017-08-10

申请号：US15581005

申请日：2017-04-28

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC: A61F2/966

CPC classification number: A61F2/966 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9665

Abstract: An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system. Methods of deploying the stent with the delivery system are also disclosed.

公开(公告)号：US20160100940A1

公开(公告)日：2016-04-14

申请号：US14974996

申请日：2015-12-18

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10T29/49405

Abstract: A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration.

Abstract translation: 提供心脏瓣膜假体和输送系统以更换心脏瓣膜。 心脏瓣膜假体包括自扩张框架，其包括具有卷曲的部分，其在折叠构型中为自扩张框架提供额外的灵活性。

公开(公告)号：US20170027694A1

公开(公告)日：2017-02-02

申请号：US15292425

申请日：2016-10-13

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

Abstract: A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis.

Abstract translation: 用于经皮递送支架假体心脏瓣膜的装置。 该装置包括内轴组件，输送护套组件，外稳定管和手柄。 鞘组件可滑动地设置在内轴上，并且包括胶囊和轴。 胶囊压缩地包含内轴上的假体。 稳定管可滑动地设置在输送护套上方，并且包括构造成从具有第二直径的第一直径的第一形状的径向可扩张的远端区域。 在第一传送状态中，远侧区域呈现第一形状，提供适于穿过患者脉管系统的低轮廓。 在第二递送状态中，远端区域具有扩大直径的第二形状，其尺寸被设计成接收胶囊，例如当缩回胶囊以植入假体时。

公开(公告)号：US20130282111A1

公开(公告)日：2013-10-24

申请号：US13905632

申请日：2013-05-30

Applicant: Medtronic, Inc.

Inventor： Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2002/9665

Abstract: A device for percutaneously delivering a stented prosthetic heart valve. The device includes an inner shaft assembly, a delivery sheath assembly, an outer stability tube, and a handle. The sheath assembly is slidably disposed over the inner shaft, and includes a capsule and a shaft. The capsule compressively contains the prosthesis over the inner shaft. The stability tube is slidably disposed over the delivery sheath, and includes a distal region configured to be radially expandable from a first shape having a first diameter to a second shape having a larger, second diameter. In a first delivery state, the distal region assumes the first shape, providing a low profile appropriate for traversing a patient's vasculature. In a second delivery state, the distal region has the expanded diameter second shape, sized to receive the capsule, such as when retracting the capsule to implant the prosthesis.

Abstract translation: 用于经皮递送支架假体心脏瓣膜的装置。 该装置包括内轴组件，输送护套组件，外稳定管和手柄。 鞘组件可滑动地设置在内轴上，并且包括胶囊和轴。 胶囊压缩地包含内轴上的假体。 稳定管可滑动地设置在输送护套上方，并且包括构造成从具有第二直径较大的第一直径的第一形状可径向扩张的远侧区域。 在第一传送状态中，远侧区域呈现第一形状，提供适于穿过患者脉管系统的低轮廓。 在第二递送状态中，远端区域具有扩大直径的第二形状，其尺寸被设计成接收胶囊，例如当缩回胶囊以植入假体时。

公开(公告)号：US20230218396A1

公开(公告)日：2023-07-13

申请号：US18188451

申请日：2023-03-22

Applicant: Medtronic, Inc.

Inventor： James Keogh ,  Joshua Dwork

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61F2/2418

Abstract: A delivery system for delivering a heart valve prosthesis includes a heart valve prosthesis and a delivery catheter. The heart valve prosthesis includes an anchoring member and an inner valve support, and further includes a radially collapsed configuration and a radially expanded configuration. The delivery catheter includes a handle, an outer shaft, an intermediate shaft, an inner shaft, and a distal tip component. The delivery catheter further includes a delivery configuration. In the delivery configuration, the outer shaft of the delivery catheter is configured to retain a first portion of the anchoring member, the intermediate shaft is configured to retain a first portion of the inner valve support, and the distal tip component is configured to retain a second end of the anchoring member and a second end of the inner valve support each in a radially compressed state.

公开(公告)号：US20230014019A1

公开(公告)日：2023-01-19

申请号：US17808436

申请日：2022-06-23

Applicant: Medtronic, Inc.

Inventor： Erik C. Griswold ,  Kenny D. Bruner ,  Joshua Dwork ,  Austin Haynes

IPC: A61F2/24

Abstract: An apparatus for hydraulic deployment and recapture of an implant includes a hydraulic implant uncovering mechanism and a hydraulic implant re-covering mechanism. The implant uncovering mechanism and the implant re-covering mechanism are independently actuateable with a fluid, and the implant uncovering mechanism is coupled to the implant re-covering mechanism by a flexible elongate tether.

公开(公告)号：US20210068950A1

公开(公告)日：2021-03-11

申请号：US17094909

申请日：2020-11-11

Applicant: MEDTRONIC, INC.

Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC: A61F2/24

Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

公开(公告)号：US20200281719A1

公开(公告)日：2020-09-10

申请号：US16807010

申请日：2020-03-02

Applicant: Medtronic, Inc.

Inventor： James Keogh ,  Joshua Dwork

IPC: A61F2/24

Abstract: A delivery system for delivering a heart valve prosthesis includes a heart valve prosthesis and a delivery catheter. The heart valve prosthesis includes an anchoring member and an inner valve support, and further includes a radially collapsed configuration and a radially expanded configuration. The delivery catheter includes a handle, an outer shaft, an intermediate shaft, an inner shaft, and a distal tip component. The delivery catheter further includes a delivery configuration. In the delivery configuration, the outer shaft of the delivery catheter is configured to retain a first portion of the anchoring member, the intermediate shaft is configured to retain a first portion of the inner valve support, and the distal tip component is configured to retain a second end of the anchoring member and a second end of the inner valve support each in a radially compressed state.