公开(公告)号：US11963873B2

公开(公告)日：2024-04-23

申请号：US17087008

申请日：2020-11-02

申请人： MEDTRONIC, INC.

发明人： Jason Quill ,  Cynthia Clague ,  Michael Green ,  Alexander J. Hill ,  Ana Menk ,  Paul Rothstein ,  Georg Bortlein

IPC分类号： A61F2/24 ,  A61B17/00 ,  A61B17/064 ,  A61B17/068

CPC分类号： A61F2/2442 ,  A61B17/068 ,  A61B2017/00243 ,  A61B2017/00331 ,  A61B2017/00349 ,  A61B2017/00783 ,  A61B2017/0649 ,  A61F2/2412 ,  A61F2002/249 ,  A61F2230/0091

摘要： Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.

公开(公告)号：US11833041B2

公开(公告)日：2023-12-05

申请号：US18067272

申请日：2022-12-16

申请人： MEDTRONIC, INC.

发明人： Jason Quill ,  Cynthia T. Clague ,  Paul T. Rothstein

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2436 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0091 ,  A61F2230/0013

摘要： Described is a prosthetic valve, comprising: an expandable stent including an inner lumen and having a first and a second end; and a spring attached to the first end of the expandable stent; wherein the expandable stent and the spring can expand radially to a desired diametric configuration in order to anchor the prosthetic valve at an implantation position in a body lumen. Related systems and methods.

公开(公告)号：US20200337839A1

公开(公告)日：2020-10-29

申请号：US16924328

申请日：2020-07-09

申请人： Medtronic, Inc.

发明人： Jason Quill ,  Paul Rothstein ,  Thomas Secord ,  Byron Johnson

IPC分类号： A61F2/24

摘要： A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis.

公开(公告)号：US10716669B2

公开(公告)日：2020-07-21

申请号：US15354187

申请日：2016-11-17

申请人： Medtronic, Inc.

发明人： Damian Jelich ,  Ana Menk ,  Jason Quill ,  Gilbert Tang

IPC分类号： A61B17/10 ,  A61F2/24

摘要： A delivery system for delivery of a radially expandable device to an implantation site in a patient, the delivery system including an elongated tubular member comprising a distal tip and an outer surface, first and second balloon portions spaced proximally from each other and the distal tip along a length of the tubular member, an annular space between the first and second balloon portions, a plurality of clip deployment tubes extendably moveable relative to the outer surface of the tubular member, and a plurality of clips, wherein each clip is moveable within a length of one of the clip deployment tubes between a retracted position and a deployed position.

公开(公告)号：US10716668B2

公开(公告)日：2020-07-21

申请号：US15479331

申请日：2017-04-05

申请人： Medtronic, Inc.

发明人： Jason Quill

IPC分类号： A61F2/24 ,  A61B17/04 ,  A61B17/00 ,  A61F2/962 ,  A61F2/95

摘要： A delivery device includes an inner shaft, an outer sheath, a nosecone, and a tether component. The outer sheath is slidably disposed over the inner shaft. The nosecone is removably coupled to the inner shaft. The nosecone includes a delivery configuration for delivery to a treatment site, a radially compressed configuration in which a portion of the nosecone is configured to traverse through a heart wall, and a radially expanded configuration in which an outer surface of the nosecone contacts an outer surface of the heart wall. The tether component includes a first end coupled to the nosecone. The nosecone is configured to plug a piercing in the heart wall when in the radially expanded configuration.

公开(公告)号：US09232995B2

公开(公告)日：2016-01-12

申请号：US13736460

申请日：2013-01-08

申请人： Medtronic, Inc.

发明人： Igor Kovalsky ,  Jason Quill ,  Daniel Glozman ,  Ilia Hariton ,  Yossi Tuval ,  Nadav Yellin

IPC分类号： A61F2/06 ,  A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2230/001 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2230/008

摘要： In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.

摘要翻译： 在一些实施例中，瓣膜假体包括入口部分，其基本上为S形并且构造成接合天然心脏心房的流出道的底部。 在一些实施例中，瓣膜假体包括腱索引导元件，其被配置为减少腱索的弯曲以减少在心脏周期期间腱索上的应力。 在一些实施例中，瓣膜假体包括具有沙漏形状的中心部分，其构造成夹住天然环带，以便在瓣膜部位内提供瓣膜假体的轴向固定。 在一些实施例中，瓣膜假体包括具有流出端的框架，所述流出端在所述假体叶片完全打开时，所述流出端被展开以在所述框架的流出端和假体叶片的流出端之间提供间隙。

公开(公告)号：US09211178B2

公开(公告)日：2015-12-15

申请号：US13777131

申请日：2013-02-26

申请人： Medtronic, Inc.

发明人： Paul Rothstein ,  Jason Quill ,  Dean Christiansen ,  Elizabeth Schotzko ,  Joel Racchini ,  Jeffrey Sandstrom ,  Cynthia Clague

IPC分类号： A61F2/00 ,  A61F2/01

CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2210/009

摘要： An embolic protection device includes a first filter configured to be disposed in a first vessel and a second filter configured to be disposed in a second vessel. A first tether extends from a proximal end of the first filter and a first magnet is coupled to the first tether. A second tether extends from a proximal end of the second filter and a second magnet is coupled to the second tether. The device is configured such that when the first filter is disposed in the first vessel and the second filter is disposed in the second vessel, the first magnet and the second magnet are magnetically coupled to each other to couple the first tether to the second tether.

摘要翻译： 栓塞保护装置包括被配置为设置在第一容器中的第一过滤器和被配置为设置在第二容器中的第二过滤器。 第一系绳从第一过滤器的近端延伸并且第一磁体联接到第一系绳。 第二系绳从第二过滤器的近端延伸并且第二磁体联接到第二系绳。 该装置被构造成使得当第一过滤器设置在第一容器中并且第二过滤器设置在第二容器中时，第一磁体和第二磁体彼此磁耦合以将第一系绳耦合到第二系绳。

公开(公告)号：US20140128726A1

公开(公告)日：2014-05-08

申请号：US13668952

申请日：2012-11-05

申请人： MEDTRONIC, INC.

发明人： Jason Quill ,  Noah Barka ,  Jason Bourgoin ,  Igor Kovalsky ,  Paul Rothstein

IPC分类号： A61F2/24 ,  A61B6/00 ,  A61B8/13

CPC分类号： A61B8/085 ,  A61B6/12 ,  A61B6/4417 ,  A61B6/481 ,  A61B6/487 ,  A61B6/503 ,  A61B6/547 ,  A61B8/0833 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/13 ,  A61B8/4254 ,  A61B8/4416 ,  A61F2/2427

摘要： Alignment of imaging modalities is disclosed. Orientation of an ultrasound imaging probe can be determined. A fluoroscopic imaging device can be aligned with respect to the orientation of the ultrasound imaging probe and a medical device can be implanted based on images obtained from the ultrasound imaging probe and the fluoroscopic imaging device.

摘要翻译： 公开了成像方式的对准。 可以确定超声成像探针的取向。 透视成像装置可以相对于超声成像探针的取向对准，并且可以基于从超声成像探针和荧光透视成像装置获得的图像来植入医疗装置。

公开(公告)号：US11833038B2

公开(公告)日：2023-12-05

申请号：US17093773

申请日：2020-11-10

申请人： MEDTRONIC, INC.

发明人： Igor Kovalsky ,  Jason Quill ,  Daniel Glozman ,  Ilia Hariton ,  Yossi Tuval ,  Nadav Yellin

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2230/001 ,  A61F2230/005 ,  A61F2230/008 ,  A61F2230/0054 ,  A61F2230/0078

摘要： In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.

公开(公告)号：US10321992B2

公开(公告)日：2019-06-18

申请号：US15012533

申请日：2016-02-01

申请人： Medtronic, Inc.

发明人： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

IPC分类号： A61F2/24

摘要： Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.