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    TRANSCATHETER PROSTHETIC HEART VALVE POST-DILATATION REMODELING DEVICES AND METHODS
    1.
    发明申请
    TRANSCATHETER PROSTHETIC HEART VALVE POST-DILATATION REMODELING DEVICES AND METHODS 有权

    公开(公告)号：US20220287835A1

    公开(公告)日：2022-09-15

    申请号：US17829464

    申请日：2022-06-01

    Applicant: Medtronic, Inc.

    Inventor： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

    IPC: A61F2/24 ,  A61M25/10 ,  A61F2/95

    Abstract: A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

    Transcatheter Prosthetic Heart Valve Delivery System with Funnel Recapturing Feature and Method
    3.
    发明申请
    Transcatheter Prosthetic Heart Valve Delivery System with Funnel Recapturing Feature and Method 有权
    经导管假手术心脏瓣膜输送系统与漏斗回收特征及方法

    公开(公告)号：US20140012369A1

    公开(公告)日：2014-01-09

    申请号：US13969784

    申请日：2013-08-19

    Applicant: Medtronic, Inc.

    Inventor： Robert Murry, III ,  Susheel Deshmukh ,  Padraig Savage ,  Matthew Rust

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2002/9517 ,  A61F2002/9534

    Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.

    Abstract translation: 用于经皮部署支架假体心脏瓣膜的输送装置。 该装置包括递送胶囊和再捕获护套。 胶囊被构造成压缩地保持假体。 重新捕获鞘包括具有多个周向间隔的流道和聚合物覆盖层的漏斗段。 流道附着在轴上，并终止于远端。 覆盖物围绕流道，并且结合到轴，但至少不是尖端。 漏斗段可以从正常状态转变成扩展状态，形成具有向远端增加的直径的漏斗形状，并且可自由转变回正常状态。 漏斗段有助于将胶囊滑动在假体的部分展开的区域上，作为重新捕获操作的一部分。 跑步者提供柱状强度，覆盖层控制漏斗段的形状。

    TRANSCATHETER PROSTHETIC HEART VALVE POST-DILATATION REMODELING DEVICES AND METHODS
    5.
    发明申请
    TRANSCATHETER PROSTHETIC HEART VALVE POST-DILATATION REMODELING DEVICES AND METHODS 审中-公开

    公开(公告)号：US20200030094A1

    公开(公告)日：2020-01-30

    申请号：US16593088

    申请日：2019-10-04

    Applicant: Medtronic, Inc.

    Inventor： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

    IPC: A61F2/24 ,  A61M25/10 ,  A61F2/95

    Abstract: A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

    Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method
    6.
    发明授权
    Transcatheter prosthetic heart valve delivery system with funnel recapturing feature and method 有权
    经导管假体心脏瓣膜输送系统，具有漏斗回收特征和方法

    公开(公告)号：US08986372B2

    公开(公告)日：2015-03-24

    申请号：US13969784

    申请日：2013-08-19

    Applicant: Medtronic, Inc.

    Inventor： Robert Murry, III ,  Susheel Deshmukh ,  Padraig Savage ,  Matthew Rust

    IPC: A61F2/24 ,  A61F2/95

    CPC classification number: A61F2/2436 ,  A61F2002/9517 ,  A61F2002/9534

    Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.

    Abstract translation: 用于经皮部署支架假体心脏瓣膜的输送装置。 该装置包括递送胶囊和再捕获护套。 胶囊被构造成压缩地保持假体。 重新捕获鞘包括具有多个周向间隔的流道和聚合物覆盖层的漏斗段。 流道附着在轴上，并终止于远端。 覆盖物围绕流道，并且结合到轴，但至少不是尖端。 漏斗段可以从正常状态转变成扩展状态，形成具有向远端增加的直径的漏斗形状，并且可自由转变回正常状态。 漏斗段有助于将胶囊滑动在假体的部分展开的区域上，作为重新捕获操作的一部分。 跑步者提供柱状强度，覆盖层控制漏斗段的形状。

    Stented transcatheter prosthetic heart valve delivery system and method
    7.
    发明授权
    Stented transcatheter prosthetic heart valve delivery system and method 有权
    支架经导管假体心脏瓣膜输送系统及方法

    公开(公告)号：US08974524B2

    公开(公告)日：2015-03-10

    申请号：US14056467

    申请日：2013-10-17

    Applicant: Medtronic, Inc.

    Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

    IPC: A61F2/24 ,  A61F2/966 ,  A61F2/95

    CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

    Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

    Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。

    STENTED TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHOD
    8.
    发明申请
    STENTED TRANSCATHETER PROSTHETIC HEART VALVE DELIVERY SYSTEM AND METHOD 有权

    公开(公告)号：US20140046435A1

    公开(公告)日：2014-02-13

    申请号：US14056467

    申请日：2013-10-17

    Applicant: Medtronic, Inc.

    Inventor： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

    Abstract: A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

    Abstract translation: 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。

    Transcatheter prosthetic heart valve post-dilatation remodeling devices and methods
    10.
    发明授权
    Transcatheter prosthetic heart valve post-dilatation remodeling devices and methods 有权

    公开(公告)号：US10449045B2

    公开(公告)日：2019-10-22

    申请号：US15252279

    申请日：2016-08-31

    Applicant: Medtronic, Inc.

    Inventor： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

    IPC: A61F2/95 ,  A61F2/24 ,  A61M25/10

    Abstract: A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

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