公开(公告)号：US20200299780A1

公开(公告)日：2020-09-24

申请号：US16805637

申请日：2020-02-28

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: C12Q1/6886 ,  C12Q1/6862 ,  C12Q1/6816 ,  B01J20/281

Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.

公开(公告)号：US20240344139A1

公开(公告)日：2024-10-17

申请号：US18580444

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillon ,  Laura Teresa Bortolin ,  Daniel Parker Salem ,  Kelly Biette ,  Sanchari Banerjee

IPC: C12Q1/6886 ,  G01N33/574

CPC classification number: C12Q1/6886 ,  G01N33/57419 ,  C12Q2600/158

Abstract: The present disclosure in one aspect provides technologies for detection of colorectal cancer, e.g., early detection of colorectal cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to colorectal cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.

公开(公告)号：US20240011993A1

公开(公告)日：2024-01-11

申请号：US18015051

申请日：2021-07-08

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillon

IPC: G01N33/574 ,  C12Q1/6886

CPC classification number: G01N33/57423 ,  C12Q1/6886 ,  C12Q2600/158

Abstract: The present disclosure in one aspect provides technologies for detection of lung cancer, e.g, early detection of lung cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to lung cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g, by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.

公开(公告)号：US20220161265A1

公开(公告)日：2022-05-26

申请号：US17493259

申请日：2021-10-04

Applicant: Mercy BioAnalytics, Inc.

Inventor： Christopher Robert Sedlak ,  Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: B01L9/06

Abstract: A column tube holder includes: a first side rail extending vertically; a second side rail extending vertically; a first shelf extending horizontally between the first side rail and the second side rail; a second shelf extending horizontally between the first side rail and the second side rail, the second shelf disposed below the first shelf; and a third shelf extending horizontally between the first side rail and the second side rail, the third shelf disposed below the second shelf. The column tube holder is composed of a conductive material, an anti-static material, and/or a static dissipative material.

公开(公告)号：US20240369560A1

公开(公告)日：2024-11-07

申请号：US18580412

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillion ,  Laura Teresa Bortolin ,  Daniel Parker Salem ,  Kelly Biette

IPC: G01N33/574 ,  G01N27/74

Abstract: The present disclosure in one aspect provides technologies for detection of pancreatic cancer, e.g., early detection of pancreatic cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to pancreatic cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.

公开(公告)号：US11786907B2

公开(公告)日：2023-10-17

申请号：US17493259

申请日：2021-10-04

Applicant: Mercy BioAnalytics, Inc.

Inventor： Christopher Robert Sedlak ,  Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: B01L9/06 ,  A47F7/28 ,  A47F7/00

CPC classification number: B01L9/06 ,  A47F7/0028 ,  A47F7/283 ,  B01L2300/12 ,  B01L2300/16

Abstract: A column tube holder includes: a first side rail extending vertically; a second side rail extending vertically; a first shelf extending horizontally between the first side rail and the second side rail; a second shelf extending horizontally between the first side rail and the second side rail, the second shelf disposed below the first shelf; and a third shelf extending horizontally between the first side rail and the second side rail, the third shelf disposed below the second shelf. The column tube holder is composed of a conductive material, an anti-static material, and/or a static dissipative material.

公开(公告)号：US11085089B2

公开(公告)日：2021-08-10

申请号：US16805637

申请日：2020-02-28

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: C12Q1/6886 ,  C12Q1/6862 ,  C12Q1/6816 ,  B01J20/281 ,  G01N30/02

Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.

公开(公告)号：US20210214806A1

公开(公告)日：2021-07-15

申请号：US17204773

申请日：2021-03-17

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: C12Q1/6886 ,  C12Q1/6862 ,  C12Q1/6816 ,  B01J20/281

Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.

公开(公告)号：US20240369558A1

公开(公告)日：2024-11-07

申请号：US18580427

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillon ,  laura Teresa Bortolin ,  Daniel Parker Salem ,  Kelly Biette ,  Ibukunoluwapo O. Zabroski

IPC: G01N33/574 ,  C12Q1/6886

Abstract: The present disclosure in one aspect provides technologies for detection of breast cancer, e.g., early detection of breast cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to breast cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.

公开(公告)号：US20230415161A1

公开(公告)日：2023-12-28

申请号：US18465361

申请日：2023-09-12

Applicant: Mercy BioAnalytics, Inc.

Inventor： Christopher Robert Sedlak ,  Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: B01L9/06 ,  A47F7/28 ,  A47F7/00

CPC classification number: B01L9/06 ,  A47F7/283 ,  A47F7/0028 ,  B01L2300/16 ,  B01L2300/12

Abstract: A column tube holder includes: a first side rail extending vertically; a second side rail extending vertically; a first shelf extending horizontally between the first side rail and the second side rail; a second shelf extending horizontally between the first side rail and the second side rail, the second shelf disposed below the first shelf; and a third shelf extending horizontally between the first side rail and the second side rail, the third shelf disposed below the second shelf. The column tube holder is composed of a conductive material, an anti-static material, and/or a static dissipative material.