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1.
公开(公告)号:US20070142413A1
公开(公告)日:2007-06-21
申请号:US10595807
申请日:2004-11-15
申请人: Michael Block , John Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Josey , Bin Wang
发明人: Michael Block , John Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Josey , Bin Wang
IPC分类号: A61K31/506 , C07D403/14 , C07D413/14
CPC分类号: C07D401/14 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/04 , C07D471/04 , C07D487/04 , C07D495/04
摘要: Compounds of formula (I): and their use in the inhibition of Trk activity are described.
摘要翻译: 描述式(I)化合物及其在抑制Trk活性中的用途。
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2.
公开(公告)号:US20100152219A1
公开(公告)日:2010-06-17
申请号:US12712659
申请日:2010-02-25
申请人: Michael Howard Block , John W. Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Anthony Josey , Bin Wang
发明人: Michael Howard Block , John W. Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Anthony Josey , Bin Wang
IPC分类号: A61K31/506 , C07D403/12
CPC分类号: C07D401/14 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/04 , C07D471/04 , C07D487/04 , C07D495/04
摘要: Compounds of formula (I): and their use in the inhibition of Trk activity are described.
摘要翻译: 描述式(I)化合物及其在抑制Trk活性中的用途。
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公开(公告)号:US07622482B2
公开(公告)日:2009-11-24
申请号:US11816376
申请日:2006-02-15
申请人: Yongxin Han , Michelle Lamb , Peter Mohr , Bin Wang , Tao Wang , Dingwei Yu
发明人: Yongxin Han , Michelle Lamb , Peter Mohr , Bin Wang , Tao Wang , Dingwei Yu
IPC分类号: A01N43/42 , A61K31/44 , C07D471/00 , C07D487/00 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号: C07D471/04 , C07D401/12 , C07D403/12 , C07D473/32
摘要: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US20080139561A1
公开(公告)日:2008-06-12
申请号:US11815140
申请日:2006-02-01
申请人: Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
发明人: Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC分类号: A61K31/4439 , A61P35/00 , C07D401/14 , C07D413/14 , C07D409/14 , A61K31/5377 , C07D401/12
CPC分类号: C07D401/12 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要: This invention relates to novel compounds having the Formula (I) to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US08324252B2
公开(公告)日:2012-12-04
申请号:US11815140
申请日:2006-02-01
申请人: Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
发明人: Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC分类号: A61K31/44 , C07D401/14
CPC分类号: C07D401/12 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要: This invention relates to novel compounds having the Formula (I) to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US20120122892A1
公开(公告)日:2012-05-17
申请号:US13357848
申请日:2012-01-25
申请人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
发明人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC分类号: A61K31/519 , A61K31/52 , C07D487/04 , C07D471/04 , A61K31/437 , A61K31/4439 , A61K31/4184 , A61P35/00 , A61P35/02 , A61K31/444 , C07D401/14 , C07D473/32 , C07D403/12
CPC分类号: C07D473/32 , C07D401/14 , C07D403/04 , C07D471/04 , C07D487/04
摘要: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US08129403B2
公开(公告)日:2012-03-06
申请号:US11816374
申请日:2006-02-15
申请人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
发明人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC分类号: A61K31/44 , C07D513/02 , C07D515/02
CPC分类号: C07D473/32 , C07D401/14 , C07D403/04 , C07D471/04 , C07D487/04
摘要: This invention relates to novel compounds having the formula (I); and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物; 及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US20080176872A1
公开(公告)日:2008-07-24
申请号:US11816374
申请日:2006-02-15
申请人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
发明人: Michelle Lamb , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC分类号: A61K31/52 , C07D487/04 , A61K31/4155 , A61P35/02 , A61P35/00 , C07D473/32
CPC分类号: C07D473/32 , C07D401/14 , C07D403/04 , C07D471/04 , C07D487/04
摘要: This invention relates to novel compounds having the formula (I); and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物; 及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号:US20090137624A1
公开(公告)日:2009-05-28
申请号:US11816376
申请日:2006-02-15
申请人: Michelle Lamb , Tao Wang , Dingwel Yu , Yongxin Han , Peter Mohr , Bin Wang
发明人: Michelle Lamb , Tao Wang , Dingwel Yu , Yongxin Han , Peter Mohr , Bin Wang
IPC分类号: A61K31/52 , C07D471/02 , A61K31/4745 , C07D473/02
CPC分类号: C07D471/04 , C07D401/12 , C07D403/12 , C07D473/32
摘要: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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10.Pyrazolyl-Amino-Substituted Pyrimidines and Their Use in the Treatment of Cancer 审中-公开
标题翻译: 吡唑基 - 氨基取代的嘧啶及其在治疗癌症中的应用公开(公告)号:US20080194606A1
公开(公告)日:2008-08-14
申请号:US11913451
申请日:2006-05-04
申请人: David Scott , Haixia Wang , Tao Wang
发明人: David Scott , Haixia Wang , Tao Wang
IPC分类号: A61K31/506 , C07D403/12 , A61P35/04
CPC分类号: C07D403/12
摘要: This invention relates to novel compounds having the formula (I), and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译: 本发明涉及具有式(I)的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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