公开(公告)号：US20240268942A1

公开(公告)日：2024-08-15

申请号：US18569539

申请日：2022-06-08

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Akihiro OKAMOTO ,  Waheed MIRAN

IPC: A61C19/06 ,  A61C8/00 ,  A61N1/05 ,  A61N1/36

CPC classification number: A61C19/06 ,  A61C8/0012 ,  A61N1/0548 ,  A61N1/36031 ,  A61N1/36034

Abstract: A peri-implantitis treatment device (1) according to the present invention includes: an electrode (14) for applying a negative electric potential to a metal portion (7) of a dental implant (8); a potential controller for controlling the electric potential of the electrode (14); and a mouthpiece (2) that holds the electrode (14) and the potential controller and is attached to the dental implant (8). The peri-implantitis treatment device (1) according to the present invention makes it possible to effectively inactivate even bacteria (colonies) that have formed biofilms hard to inactivate by antibiotics in deep periodontal pockets where mechanical cleaning is difficult.

公开(公告)号：US20240279635A1

公开(公告)日：2024-08-22

申请号：US18569545

申请日：2022-06-08

Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

Inventor： Akihiro OKAMOTO ,  Waheed MIRAN

IPC: C12N13/00 ,  A61L2/03 ,  C12N1/20 ,  C12Q1/02

CPC classification number: C12N13/00 ,  A61L2/03 ,  C12N1/20 ,  C12Q1/02 ,  A61L2202/24

Abstract: A biofilm activity adjusting method according to the present invention, includes: bringing a medium containing 2-hydroxy-1,4-naphthoquinone and water into contact with a conductor having a bacterium-derived biofilm; and adjusting the biofilm activity by applying, to the conductor, a first electric potential of higher than a lower limit value of an electric potential window and −0.4 V or lower with respect to a silver/silver chloride electrode reference. The biofilm activity adjusting method according to the present invention makes it possible to obtain an excellent activity adjusting effect on the biofilm.