公开(公告)号：US3892773A

公开(公告)日：1975-07-01

申请号：US36217273

申请日：1973-05-21

Applicant: ROUSSEL UCLAF

Inventor： ALLAIS ANDRE ,  MEIER JEAN ,  DUBE JACQUES

IPC: C07D335/02 ,  C07D309/06 ,  C07D65/04 ,  C07D7/04

CPC classification number: C07D309/06

Abstract: Novel 2-phenyl ethanol derivatives of the formula

WHEREIN X is selected from the group consisting of oxygen and sulfur, Hal is halogen, R is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and Y is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms and when R is alkyl, they exist in the form of racemates or optically active isomers having analgesic and anti-inflammatory activity.

Abstract translation: 式WHEREIN X的新型2-苯基乙醇衍生物选自氧和硫，Hal是卤素，R选自氢和1至4个碳原子的烷基，Y选自 由氢和1至18个碳原子的有机羧酸的酰基组成，当R是烷基时，它们以具有止痛和消炎活性的外消旋物或旋光异构体的形式存在。