公开(公告)号：US3906096A

公开(公告)日：1975-09-16

申请号：US44756174

申请日：1974-03-04

Applicant: ROUSSEL UCLAF

Inventor： BUCOURT ROBERT ,  PIERDET ANDRE ,  SALMON JEAN

IPC: C07J1/00 ,  A61K31/56

CPC classification number: C07J1/0088

Abstract: 11 Beta -ALKOXY- Delta 4-GONENES OF THE FORMULA
WHEREIN R and X are alkyl of 1 to 4 carbon atoms, R1 is a saturated or unsaturated hydrocarbon of 1 to 6 carbon atoms, R2 is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 18 carbon atoms and Y and Y'' are selected from the group consisting of hydrogen and methyl and the enolic esters thereof with an organic carboxylic acid of 1 to 18 carbon atoms which possess anti-androgenic and anti-estrogenic activity, their preparation and novel intermediates.

Abstract translation: 其中R和X为1-4个碳原子的烷基，R1为1至6个碳原子的饱和或不饱和烃基，R2选自氢和酰基 的1至18个碳原子的有机羧酸，Y和Y'选自氢和甲基及其烯醇与具有1至18个碳原子的有机羧酸，其具有抗雄激素和抗 - 雌激素活性，其制备和新型中间体。