公开(公告)号：US06240322B1

公开(公告)日：2001-05-29

申请号：US09186326

申请日：1998-11-04

申请人： Randall M. Peterfeso ,  Mary Lee Cole ,  Larry L. Hum ,  Michael P. Campbell

发明人： Randall M. Peterfeso ,  Mary Lee Cole ,  Larry L. Hum ,  Michael P. Campbell

IPC分类号： A61N105

CPC分类号： A61N1/057

摘要： A medical device is insertable and/or implantable into a body of a patient. The medical device includes a plurality of hollow and/or collapsible tines which are adapted to assist in deployment of the medical device into the body and in preventing inadvertent removal or dislodging of the medical device from the body. The tines are coupled to the medical device body at a coupling end and extend away from the device to a free end. The tines can have a number of configurations such as cylindrical or cone shaped. In addition, the cross section of the free end of the tines can be elliptical, where the free end extends to a tip. Another cross section includes a semi-circle including an open portion which can face towards or away from the medical device body. The tines also include coiled structures which can have a radial axis perpendicular to the radial axis of the medical device.

摘要翻译： 医疗装置可插入和/或植入患者体内。 医疗装置包括多个中空和/或可收缩的齿，其适于帮助将医疗装置部署到体内并防止医疗装置从体内无意中移除或移走。 齿在耦合端耦合到医疗装置本体并且远离装置延伸到自由端。 齿可以具有多个构造，例如圆柱形或锥形。 此外，齿的自由端的横截面可以是椭圆形，其中自由端延伸到尖端。 另一横截面包括一个半圆，其包括可面向或远离医疗装置主体的开放部分。 齿还包括可以具有垂直于医疗装置的径向轴线的径向轴线的螺旋结构。

公开(公告)号：US06212434B1

公开(公告)日：2001-04-03

申请号：US09120824

申请日：1998-07-22

申请人： Avram Scheiner ,  William Hsu ,  David M. Flynn ,  Qingsheng Zhu ,  John E. Heil ,  Ronald W. Heil, Jr. ,  Curtis C. Lindstrom ,  Robert S. Booker, III ,  Yayun Lin ,  Peter T. Kelley ,  Jay A. Warren ,  Gerrard M. Carlson ,  Carol Werlein ,  Aaron W. Janke ,  Mary Lee Cole ,  Jeffrey T. Bartig ,  Gary W. Goebel ,  Douglas A. Heitkamp ,  Randall M. Peterfeso

发明人： Avram Scheiner ,  William Hsu ,  David M. Flynn ,  Qingsheng Zhu ,  John E. Heil ,  Ronald W. Heil, Jr. ,  Curtis C. Lindstrom ,  Robert S. Booker, III ,  Yayun Lin ,  Peter T. Kelley ,  Jay A. Warren ,  Gerrard M. Carlson ,  Carol Werlein ,  Aaron W. Janke ,  Mary Lee Cole ,  Jeffrey T. Bartig ,  Gary W. Goebel ,  Douglas A. Heitkamp ,  Randall M. Peterfeso

IPC分类号： A61N105

CPC分类号： A61N1/0573 ,  A61N1/0563

摘要： A single-pass endocardial lead electrode adapted for implantation in, on or about the heart and for connection to a system for monitoring or stimulating cardiac activity includes a lead body which is adapted for implantation within a single chamber of the heart, or multiple chambers of the heart. The lead includes a first distal end electrode which has a first electrical conducting surface. The lead body also has a second electrode which has a second electrical conducting surface. The first and second electrodes are either passively or actively attached to the wall of the heart. The lead body also includes a curved portion which facilitates the positioning of the second electrode. The main lead body alternatively includes a recess into which an atrial lead body and an active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element can also be moved by turning the terminal pin. The lead body can also include multiple legs, each leg carrying an electrode. The lead is attached to a pulse generator for producing pulses to the multiple sites within the heart. A movement assembly for advancing a helix is also included within the legs and comprises an externally threaded collar which engages with an internally threaded housing or housing insert. The lead further includes a helical tip which has high impedance. The electrode has at least one features of the group: the helix having a coating of an insulating material on its surface, the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, a porous conductive element at a base of the helix, and a porous conductive element at the end of the electrode having an insulating coating cover from 5-95% of the surface of the porous conductive element. The porous element may further provide a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart.

公开(公告)号：US06501994B1

公开(公告)日：2002-12-31

申请号：US09121288

申请日：1998-07-22

申请人： Aaron W. Janke ,  Mary Lee Cole ,  Ronald W. Heil, Jr. ,  Jeffrey T. Bartig ,  Gary W Goebel ,  Douglas A Heitkamp ,  Randall M. Peterfeso

发明人： Aaron W. Janke ,  Mary Lee Cole ,  Ronald W. Heil, Jr. ,  Jeffrey T. Bartig ,  Gary W Goebel ,  Douglas A Heitkamp ,  Randall M. Peterfeso

IPC分类号： A61N105

CPC分类号： A61N1/0573

摘要： An implantable lead, being either a fixed or retractable/extendable lead, having a distal tip electrode is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The electrode includes a mechanical fastener such as a fixation helix for securing the electrode to cardiac tissue, which may or may not be electrically active. The implantable electrode with a helical tip includes an electrode which has a distal end and a proximal end. A helix is disposed within the electrode, where the helix is aligned along a radial axis of the electrode. The electrode further includes one or more of the following features: the helix having a coating of an insulating material on a surface of the helix, a porous conductive surface at a base of the helix, a porous conductive element at the end of the electrode having an insulating coating covering from 5-95% of the surface of the porous conductive element. The electrode may farther include an electrode tip having a porous electrical conductive element, such as a mesh screen, disposed on a surface at the distal end of the electrode tip, which can be used as a sensing or pacing interface with the cardiac tissue.

摘要翻译： 具有远端尖端电极的可植入引线（或者是固定的或可伸缩的引线）适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 电极包括机械紧固件，例如用于将电极固定到心脏组织的固定螺旋，其可以是或不是电活动的。 具有螺旋尖端的可植入电极包括具有远端和近端的电极。 螺旋线设置在电极内，其中螺旋沿着电极的径向轴线排列。 电极还包括以下特征中的一个或多个：螺旋具有在螺旋表面上的绝缘材料的涂层，在螺旋的基底处的多孔导电表面，在电极末端的多孔导电元件， 覆盖多孔导电元件表面的5-95％的绝缘涂层。 电极可以进一步包括具有设置在电极尖端的远端的表面上的多孔导电元件（例如网眼丝网）的电极末端，其可以用作与心脏组织的感测或起搏界面。

公开(公告)号：US06505082B1

公开(公告)日：2003-01-07

申请号：US09643125

申请日：2000-08-21

申请人： Avram Scheiner ,  William Hsu ,  David M. Flynn ,  Qingsheng Zhu ,  John E. Heil ,  Ronald W. Heil, Jr. ,  Curtis C. Lindstrom ,  Robert S. Booker, III ,  Yayun Lin ,  Peter T. Kelley ,  Jay A. Warren ,  Gerrard M. Carlson ,  Carol Werlein ,  Aaron W. Janke ,  Mary Lee Cole ,  Jeffrey T. Bartig ,  Gary W Goebel ,  Douglas A Heitkamp ,  Randall M. Peterfeso

发明人： Avram Scheiner ,  William Hsu ,  David M. Flynn ,  Qingsheng Zhu ,  John E. Heil ,  Ronald W. Heil, Jr. ,  Curtis C. Lindstrom ,  Robert S. Booker, III ,  Yayun Lin ,  Peter T. Kelley ,  Jay A. Warren ,  Gerrard M. Carlson ,  Carol Werlein ,  Aaron W. Janke ,  Mary Lee Cole ,  Jeffrey T. Bartig ,  Gary W Goebel ,  Douglas A Heitkamp ,  Randall M. Peterfeso

IPC分类号： A61N105

CPC分类号： A61N1/0573 ,  A61N1/0563

摘要： A single-pass endocardial lead electrode adapted for implantation in, on or about the heart and for connection to a system for monitoring or stimulating cardiac activity includes a lead body which is adapted for implantation within a single chamber of the heart, or multiple chambers of the heart. The lead includes a first distal end electrode which has a first electrical conducting surface. The lead body also has a second electrode which has a second electrical conducting surface. The first and second electrodes are either passively or actively attached to the wall of the heart. The lead body also includes a curved portion which facilitates the positioning of the second electrode. The main lead body alternatively includes a recess into which an atrial lead body and an active fixation element attached to one end can travel from a recessed position to a position for fixation to the wall of the heart. The active fixation element can also be moved by turning the terminal pin. The lead body can also include multiple legs, each leg carrying an electrode. The lead is attached to a pulse generator for producing pulses to the multiple sites within the heart. A movement assembly for advancing a helix is also included within the legs and comprises an externally threaded collar which engages with an internally threaded housing or housing insert. The lead further includes a helical tip which has high impedance. The electrode has at least one features of the group: the helix having a coating of an insulating material on its surface, the helix having its surface beyond the distal end of the electrode and the distal end of the electrode having a porous conductive surface at a base of the helix, a porous conductive element at a base of the helix, and a porous conductive element at the end of the electrode having an insulating coating cover from 5-95% of the surface of the porous conductive element. The porous element may further provide a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart.

公开(公告)号：US07953496B2

公开(公告)日：2011-05-31

申请号：US10411775

申请日：2003-04-11

申请人： Mary Lee Cole

发明人： Mary Lee Cole

IPC分类号： A61N1/00 ,  A61B5/04

CPC分类号： A61N1/05 ,  H01R4/029 ,  H01R4/22 ,  H01R2201/12 ,  Y10S439/909 ,  Y10T29/49181

摘要： An implantable lead for a medical device with an isolated contact connection for connecting a conductor to a contact reduces the opportunity for conductor material to migrate to a contact or into a patient. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, at least one coupling. The lead has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact. There is an isolation space created between the conductor and the contact to prevent the weld from containing conductor material.

摘要翻译： 用于具有用于将导体连接到接触件的隔离接触连接的医疗设备的可植入引线减少了导体材料迁移到接触或进入患者的机会。 所述可植入引线包括具有近端和远端的引线本体，至少一个导体，至少一个接触部，所述至少一个触点承载在所述近端上，所述至少一个触点承载在所述远端上，至少一个联接器。 导线具有外表面。 导体容纳在引线主体中并且从引线近端延伸到远端。 导线是电绝缘的。 在近端承载的触点与导体电连接。 耦合具有导体耦合和接触耦合。 导体耦合放置在导体上并连接到导体上。 接触耦合器离开引线主体并具有焊接以将触头耦合件连接到触点。 在导体和接触件之间产生隔离空间，以防止焊缝包含导体材料。

公开(公告)号：US08000802B2

公开(公告)日：2011-08-16

申请号：US10131106

申请日：2002-04-22

申请人： Brian T. Stolz ,  Xavier Pardo ,  Mary Lee Cole

发明人： Brian T. Stolz ,  Xavier Pardo ,  Mary Lee Cole

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  Y10S439/909 ,  Y10T29/49117 ,  Y10T29/49151 ,  Y10T29/49181

摘要： An implantable lead for a medical device with a coplanar coupling for connecting a conductor to a contact reduces conductor bending moments to improve lead reliability. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, and at least one coupling. The lead body has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is also electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact. The contact coupling is configured to exit the conductor lumen and mate with the contact while retaining the conductor coplanar to the lead body.

摘要翻译： 具有用于将导体连接到接触件的共面耦合的用于医疗装置的可植入引线减少导体弯曲力矩以提高导线的可靠性。 可植入引线包括具有近端和远端的引线主体，至少一个导体，至少一个接触部，其承载在近端上，至少一个触点承载在远端上，以及至少一个联接器。 引线体具有外表面。 导体容纳在引线主体中并且从引线近端延伸到远端。 导体也是电绝缘的。 在近端承载的触点与导体电连接。 耦合具有导体耦合和接触耦合。 导体耦合放置在导体上并连接到导体上。 接触耦合器离开引线主体并具有焊接以将触头耦合件连接到触点。 接触联接器被配置为离开导体管腔并与接触件配合，同时将导体保持与引线体共面。

公开(公告)号：US07184840B2

公开(公告)日：2007-02-27

申请号：US10128883

申请日：2002-04-22

申请人： Brian Stolz ,  Mary Lee Cole ,  Xavier E. Pardo

发明人： Brian Stolz ,  Mary Lee Cole ,  Xavier E. Pardo

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  H01R4/029 ,  H01R4/22 ,  H01R2201/12 ,  Y10S439/909 ,  Y10T29/49181

摘要： An implantable lead for a medical device with an isolated contact connection for connecting a conductor to a contact reduces the opportunity for conductor material to migrate to a contact or into a patient. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, at least one coupling. The lead has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact. There is an isolation space created between the conductor and the contact to prevent the weld from containing conductor material.

摘要翻译： 用于具有用于将导体连接到接触件的隔离接触连接的医疗设备的可植入引线减少了导体材料迁移到接触或进入患者的机会。 所述可植入引线包括具有近端和远端的引线本体，至少一个导体，至少一个接触部，所述至少一个触点承载在所述近端上，所述至少一个触点承载在所述远端上，至少一个联接器。 导线具有外表面。 导体容纳在引线主体中并且从引线近端延伸到远端。 导线是电绝缘的。 在近端承载的触点与导体电连接。 耦合具有导体耦合和接触耦合。 导体耦合放置在导体上并连接到导体上。 接触耦合器离开引线主体并具有焊接以将触头耦合件连接到触点。 在导体和接触件之间产生隔离空间，以防止焊缝包含导体材料。

公开(公告)号：US6097986A

公开(公告)日：2000-08-01

申请号：US992039

申请日：1997-12-17

申请人： Aaron W. Janke ,  Mary Lee Cole

发明人： Aaron W. Janke ,  Mary Lee Cole

IPC分类号： A61N1/05

CPC分类号： A61N1/0573

摘要： A retractable lead having a distal tip electrode is adapted for implantation on or about the heart and for connection to a system for monitoring or stimulating cardiac activity. The electrode includes a fixation helix for securing the electrode to cardiac tissue, which may or may not be electrically active. The electrode further includes an electrode tip having a mesh screen disposed on a surface at the distal end of the electrode tip, which can be used as a sensing or pacing interface with the cardiac tissue. The mesh screen provides a guiding mechanism for the helix as it travels out of the electrode for securing the electrode to the heart or other muscle or organ. The guiding mechanism may include a groove within the mesh screen. Alternatively, the guiding mechanism includes a guiding bar on which the fixation helix rides on during extension or retraction.

摘要翻译： 具有远端尖端电极的可伸缩引线适于植入在心脏上或其周围，并用于连接到用于监测或刺激心脏活动的系统。 电极包括用于将电极固定到心脏组织的固定螺旋，其可以是或不是电活动的。 电极还包括具有设置在电极末端的远端的表面上的网眼的电极末端，其可以用作与心脏组织的感测或起搏界面。 网状筛网提供了一种用于螺旋线的导引机构，因为其行进出电极以将电极固定到心脏或其他肌肉或器官。 引导机构可以包括网筛内的凹槽。 或者，引导机构包括引导杆，其中固定螺旋在延伸或缩回期间骑行。

公开(公告)号：US08306631B2

公开(公告)日：2012-11-06

申请号：US13198910

申请日：2011-08-05

申请人： Mary Lee Cole ,  Xavier Pardo ,  Brian T. Stolz

发明人： Mary Lee Cole ,  Xavier Pardo ,  Brian T. Stolz

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  Y10S439/909 ,  Y10T29/49117 ,  Y10T29/49151 ,  Y10T29/49181

摘要： An implantable lead for a medical device with a coplanar coupling for connecting a conductor to a contact reduces conductor bending moments to improve lead reliability. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, and at least one coupling. The lead body has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is also electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact. The contact coupling is configured to exit the conductor lumen and mate with the contact while retaining the conductor coplanar to the lead body.

摘要翻译： 具有用于将导体连接到接触件的共面耦合的用于医疗装置的可植入引线减少导体弯曲力矩以提高导线的可靠性。 可植入引线包括具有近端和远端的引线主体，至少一个导体，至少一个接触部，其承载在近端上，至少一个触点承载在远端上，以及至少一个联接器。 引线体具有外表面。 导体容纳在引线主体中并且从引线近端延伸到远端。 导体也是电绝缘的。 在近端承载的触点与导体电连接。 耦合具有导体耦合和接触耦合。 导体耦合放置在导体上并连接到导体上。 接触耦合器离开引线主体并具有焊接以将触头耦合件连接到触点。 接触联接器被配置为离开导体管腔并与接触件配合，同时将导体保持与引线体共面。

公开(公告)号：US20110202118A1

公开(公告)日：2011-08-18

申请号：US13096032

申请日：2011-04-28

申请人： Mary Lee Cole

发明人： Mary Lee Cole

IPC分类号： A61N1/05 ,  H01R43/048

CPC分类号： A61N1/05 ,  H01R4/029 ,  H01R4/22 ,  H01R2201/12 ,  Y10S439/909 ,  Y10T29/49181

摘要： An implantable lead for a medical device with an isolated contact connection for connecting a conductor to a contact reduces the opportunity for conductor material to migrate to a contact or into a patient. The implantable lead comprises a lead body having a proximal end and a distal end, at least one conductor, at least one contact carried on the proximal end, at least one contact carried on the distal end, at least one coupling. The lead has an exterior surface. The conductor is contained in the lead body and extends from the lead proximal end to the distal end. The conductor is electrically insulated. The contact carried on the proximal end is electrically connected to the conductor. The coupling has a conductor coupling and a contact coupling. The conductor coupling is placed over the conductor and attached to the conductor. The contact coupling exits the lead body and has a weld to connect the contact coupling to the contact. There is an isolation space created between the conductor and the contact to prevent the weld from containing conductor material.

摘要翻译： 用于具有用于将导体连接到接触件的隔离接触连接的医疗设备的可植入引线减少了导体材料迁移到接触或进入患者的机会。 所述可植入引线包括具有近端和远端的引线本体，至少一个导体，至少一个接触部，所述至少一个触点承载在所述近端上，所述至少一个触点承载在所述远端上，至少一个联接器。 导线具有外表面。 导体容纳在引线主体中并且从引线近端延伸到远端。 导线是电绝缘的。 在近端承载的触点与导体电连接。 耦合具有导体耦合和接触耦合。 导体耦合放置在导体上并连接到导体上。 接触耦合器离开引线主体并具有焊接以将触头耦合件连接到触点。 在导体和接触件之间产生隔离空间，以防止焊缝包含导体材料。