公开(公告)号：US09943466B1

公开(公告)日：2018-04-17

申请号：US15622238

申请日：2017-06-14

Applicant: Research Triangle Institute ,  The University of North Carolina at Chapel Hill

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Sarah Dorothy Shepherd ,  Sandra Cordel O'Buckley ,  Andrea Gail Neely

IPC: A61K9/16 ,  A61K6/00 ,  A61K9/00 ,  A61K47/42

CPC classification number: A61K6/0067 ,  A61K6/0002 ,  A61K9/0002 ,  A61K9/1647 ,  A61K47/42 ,  A61K2300/00

Abstract: The disclosure provides biocompatible dental material that is moldable and biodegradable and provides sustained and/or controlled delivery of one or more local anesthetics within a dental cavity or space. Such dental material is customizable for the size and shape needed for a particular patient or particular application. The dental material may also provide customizable sustained and/or controlled delivery of one or more local anesthetics.

公开(公告)号：US10292909B2

公开(公告)日：2019-05-21

申请号：US15918026

申请日：2018-03-12

Applicant: Research Triangle Institute ,  The University of North Carolina at Chapel Hill

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Sarah Dorothy Shepherd ,  Sandra Cordel O'Buckley ,  Andrea Gail Neely

IPC: A61K6/00 ,  A61K47/42 ,  A61K9/00 ,  A61K9/06 ,  A61K47/46 ,  A61K9/50 ,  A61K31/00

Abstract: The disclosure provides biocompatible dental material that is moldable and biodegradable and provides sustained and/or controlled delivery of one or more local anesthetics within a dental cavity or space. Such dental material is customizable for the size and shape needed for a particular patient or particular application. The dental material may also provide customizable sustained and/or controlled delivery of one or more local anesthetics.

公开(公告)号：US11078411B2

公开(公告)日：2021-08-03

申请号：US16071024

申请日：2017-01-17

Applicant: Research Triangle Institute

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Chasity Antoninette Norton ,  Sarah Dorothy Shepherd ,  Nicolas Daniel Huffman ,  Jeffrey Brent Mecham

IPC: C09K8/92 ,  E21B47/11 ,  C09K8/60 ,  C09K8/70 ,  C09K8/03

Abstract: The present disclosure relates to delivery and release systems wherein a plurality of particles is provided, and the particles are formed of a vehicle component and a cargo component. The systems and methods particularly can be useful in delivery of various chemicals to a petroleum reservoir. The vehicle component can undergo a change in situ such that at least a portion of the cargo component is released.

公开(公告)号：US20190031951A1

公开(公告)日：2019-01-31

申请号：US16071024

申请日：2017-01-17

Applicant: Research Triangle Institute

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Chasity Antoninette Norton ,  Sarah Dorothy Shepherd ,  Nicolas Daniel Huffman ,  Jeffrey Brent Mecham

IPC: C09K8/92 ,  C09K8/70

Abstract: The present disclosure relates to delivery and release systems wherein a plurality of particles is provided, and the particles are formed of a vehicle component and a cargo component. The systems and methods particularly can be useful in delivery of various chemicals to a petroleum reservoir. The vehicle component can undergo a change in situ such that at least a portion of the cargo component is released.

公开(公告)号：US20180325781A1

公开(公告)日：2018-11-15

申请号：US15918026

申请日：2018-03-12

Applicant: Research Triangle Institute ,  The University of North Carolina at Chapel Hill

Inventor： Leah Marie Johnson ,  Ginger Denison Rothrock ,  Sarah Dorothy Shepherd ,  Sandra Cordel O'Buckley ,  Andrea Gail Neely

IPC: A61K6/00 ,  A61K9/16 ,  A61K47/42 ,  A61K9/00

CPC classification number: A61K6/0067 ,  A61K6/0002 ,  A61K9/006 ,  A61K9/06 ,  A61K9/5026 ,  A61K31/00 ,  A61K47/42 ,  A61K47/46 ,  A61K2300/00

Abstract: The disclosure provides biocompatible dental material that is moldable and biodegradable and provides sustained and/or controlled delivery of one or more local anesthetics within a dental cavity or space. Such dental material is customizable for the size and shape needed for a particular patient or particular application. The dental material may also provide customizable sustained and/or controlled delivery of one or more local anesthetics.