公开(公告)号：US20160234904A1

公开(公告)日：2016-08-11

申请号：US15015810

申请日：2016-02-04

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke NAGAI ,  Keisuke OGAWA ,  Masato WATANABE ,  Kumiko JINGU ,  Masanori FUJIWARA ,  Tomoyuki YAMAZAKI

IPC: H05B33/08 ,  G01N21/33

CPC classification number: H05B33/0851 ,  G01N21/33 ,  G01N2201/0621 ,  G01N2201/0638 ,  G01N2201/0692 ,  G01N2201/0695

Abstract: Provided is an optical analyzer for performing a feedback control on the amount of light emitted from an LED as a light source, in which the configuration of an optical system is made simple and the degree of freedom in optical system arrangement is secured. An optical member 2 for focusing most of light while discharging part of the light as unfocused light is provided on an optical path from a light casting unit 1 to a sample cell 3. The optical member 2 can be achieved with a simple configuration, for example, two ball lenses spaced apart by a predetermined distance from each other. The light focused by the optical member 2 is cast as measurement light into the sample cell 3. Meanwhile, a second photodetector 5 is arranged at a position where the unfocused light reaches. The second photodetector 5 generates a detection signal in accordance with the amount of light that has entered the second photodetector 5 as monitored light, and a drive current to be supplied to an LED is controlled through a drive current controlling unit 6 and a current source 7 such that the amount of light is maintained at a fixed level.

Abstract translation: 提供了一种用于对从光源发出的光量进行反馈控制的光学分析器，其中光学系统的结构简单且光学系统布置的自由度得到确保。 在从光铸造单元1到样品池3的光路上设置有用于聚焦大部分光的光学构件2，同时以未聚焦的光排出部分光。光学构件2可以以简单的构造实现，例如 ，彼此隔开预定距离的两个球透镜。 将由光学构件2聚焦的光作为测量光铸造到样品池3中。同时，第二光电检测器5布置在未聚焦的光到达的位置。 第二光电检测器5根据作为监视光进入第二光电检测器5的光量产生检测信号，通过驱动电流控制单元6和电流源7控制提供给LED的驱动电流 使得光量保持在固定的水平。

公开(公告)号：US20200282337A1

公开(公告)日：2020-09-10

申请号：US16648963

申请日：2018-06-21

Applicant: Shimadzu Corporation

Inventor： Kumiko JINGU

IPC: B01D19/00 ,  G01N30/34 ,  B01D15/16

Abstract: The degassing device includes a degassing flow path, a vacuum chamber, a vacuum pump, an inlet flow path, an outlet flow path, a drain flow path, a downstream side switching unit, and a controller. The degassing flow path is made of a gas-permeable, liquid-impermeable tube, and is accommodated in the vacuum chamber. The inlet flow path is for introducing a mobile phase to the degassing flow path, and the outlet flow path is for causing a mobile phase which has passed through the degassing flow path to flow out. The drain flow path is provided separately from the outlet flow path and is configured to drain the mobile phase in the degassing flow path from the degassing flow path. The downstream side switching unit is configured to switch the downstream end of the degassing flow path so as to be connected to either the outlet flow path or the drain flow path. The controller controls the operation of the downstream side switching unit, and is configured to connect the downstream end of the degassing flow path to the drain flow path at a predetermined timing when feeding of the mobile phase by the liquid feeding pump is stopped to drain the mobile phase in the degassing flow path through the drain flow path.

公开(公告)号：US20160313248A1

公开(公告)日：2016-10-27

申请号：US15135626

申请日：2016-04-22

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke NAGAI ,  Keisuke OGAWA ,  Masato WATANABE ,  Kumiko JINGU ,  Masanori FUJIWARA ,  Tomoyuki YAMAZAKI

IPC: G01N21/64 ,  G01N21/25 ,  G01N21/31

CPC classification number: G01N21/645 ,  G01N21/255 ,  G01N2021/641 ,  G01N2201/06153

Abstract: Light emitted from a light casting unit 1 including an LED as its light source is cast into a sample cell 2, and a photodetector 3 is placed at a position where the resultant passing light can be detected. The LED is driven to blink, and a data extracting section 71 extracts data obtained in a period in which the LED is turned on, as data (absorbance data) in which absorption of light by the sample solution is reflected. Moreover, in the case where a fluorescent component is contained in the sample solution, fluorescent light is emitted by the cast light serving as excitation light. Even after the excitation light ceases, the emission of the fluorescent light continues for a short time, and hence the data extracting section 71 extracts data obtained immediately after the LED is turned off, as data (fluorescence data) in which the fluorescent light is reflected. An absorbance computing section 72 calculates absorbance based on the absorbance data, and a fluorescence computing section 73 calculates fluorescence intensity based on the fluorescence data. Accordingly, it is possible to simultaneously perform an absorbance measurement and a fluorescence measurement on one sample while using one photodetector and thus simplifying the configuration of an optical system.

Abstract translation: 从包括LED作为其光源的光铸造单元1发射的光被投射到样品池2中，并且将光电检测器3放置在可以检测所得到的通过光的位置。 LED被驱动闪烁，并且数据提取部71提取在LED被接通的时段中获得的数据作为反映样品溶液的光吸收的数据（吸光度数据）。 此外，在样品溶液中含有荧光成分的情况下，作为激发光的投射光发出荧光。 即使在激发光停止之后，荧光的发射持续很短的时间，因此数据提取部71提取在关闭LED之后立即获得的数据作为反射荧光的数据（荧光数据） 。 吸光度计算部72基于吸光度数据计算吸光度，荧光运算部73基于荧光数据计算荧光强度。 因此，可以在使用一个光电检测器的同时对一个样品进行吸光度测量和荧光测量，从而简化了光学系统的结构。