-
1.发明申请公开(公告)号：US20230132731A1
公开(公告)日：2023-05-04
申请号：US17971606
申请日：2022-10-23
Applicant: SHIMADZU CORPORATION
Inventor： Keisuke OGAWA , Andy SASAKI , Kerry HILL , Timothy LEE
Abstract: In a liquid chromatographic system, a processor is configured to analyze a sample through a first stream which is an analysis flow path including a first column, to obtain at least one of a result of analysis for quality control of the first stream and information that specifies a sample to be analyzed in the first stream, to specify, among two or more combinations of a cleaning method and a cleaning execution condition, a first combination including an execution condition to which at least one of the result of analysis for quality control and the information corresponds, and to drive one or more cleaning pumps in accordance with the cleaning method included in the first combination.
-
公开(公告)号：US20230136050A1
公开(公告)日：2023-05-04
申请号：US17971605
申请日：2022-10-23
Applicant: SHIMADZU CORPORATION
Inventor： Keisuke OGAWA , Andy SASAKI , Kerry HILL , Timothy LEE
Abstract: A liquid chromatographic system includes a column, a needle, a valve, a pump, and an analysis flow path. The valve sets the analysis flow path by switching between a first flow path through which an eluent flows from the valve to the column via the needle and a second flow path through which the eluent flows from the valve to the column not via the needle. The first flow path can be cleaned by drive of a first cleaning pump while the first flow path is set, and the second flow path can be cleaned by drive of the first cleaning pump while the second flow path is set.
-
公开(公告)号：US20210231621A1
公开(公告)日：2021-07-29
申请号：US17054788
申请日：2018-05-16
Applicant: SHIMADZU CORPORATION
Inventor： Keisuke OGAWA
IPC: G01N30/02
Abstract: The liquid delivery device includes a liquid delivery controller configured to operate, in a complementary manner, a primary plunger pump and a secondary plunger pump of each of a first liquid delivery pump and a second liquid delivery pump so that the first liquid delivery pump and the second liquid delivery pump perform continuous liquid delivery at a preset flow rate to each other, and a forcible synchronization part configured to forcibly synchronize operation states of the secondary plunger pumps of the first liquid delivery pump and the second liquid delivery pump by operating the primary plunger pump and the secondary plunger pump of the first liquid delivery pump and the second liquid delivery pump at the calculated operation speed.
-
公开(公告)号：US20210156376A1
公开(公告)日：2021-05-27
申请号：US16612380
申请日：2017-07-03
Applicant: SHIMADZU CORPORATION
Inventor： Keisuke OGAWA , Shinya IMAMURA
Abstract: A liquid feeding device includes a primary plunger pump; a secondary plunger pump connected downstream; a check valve provided between the primary plunger pump and the secondary plunger pump; a primary pressure sensor that detects a pressure in the pump chamber of the primary plunger pump; a liquid feeding control part configured to control operations of the primary plunger pump and the secondary plunger pump; and a liquid leakage detector configured to detect liquid leakage in the check valve based on a change in an output value of the primary pressure sensor during the waiting time. The liquid feeding control part is configured to control the operation of the primary plunger pump so that a waiting time, where the primary plunger pump stops without operating, is present while a discharge operation by the secondary plunger pump is performed after a suction by the primary plunger pump is completed.
-
公开(公告)号：US20200278329A1
公开(公告)日：2020-09-03
申请号：US16648077
申请日：2017-10-23
Applicant: SHIMADZU CORPORATION
Inventor： Jun YANAGIBAYASHI , Shinya IMAMURA , Keisuke OGAWA , Masataka NIKKO , Shinichi FUJISAKI
Abstract: The liquid feeding device includes a discharge speed calculation part configured to calculate a discharge speed v of the plunger pump so that a converted value LATM under an atmospheric pressure of a flow rate LPRE of the mobile phase discharged to the discharge channel from the pump part becomes a set flow rate LSET using a volume V of the mobile phase in the pump chamber of the closing pump immediately before the precompression process is started, a volume ΔV reduced due to the precompression process of the mobile phase in the pump chamber of the closing pump, and a feeding pressure P; and a discharge operation controller configured to control a discharge speed of the plunger pump to a discharge speed v calculated by the discharge speed calculation part.
-
Patent Agency Ranking
公开(公告)号：US20220146473A1
公开(公告)日：2022-05-12
申请号：US17438418
申请日：2019-03-13
Applicant: SHIMADZU CORPORATION
Inventor： Tomohiro GOMI , Daisuke KITABAYASHI , Shinya IMAMURA , Keisuke OGAWA
Abstract: A liquid chromatographic system (1) includes an analysis flow path (12) to which at least one liquid sending pump (14) is connected and through which liquid that is sent by the liquid sending pump (14) flows, a sample injector (4) that injects a sample into the analysis flow path (12), a separation column (6) that is provided on the analysis flow path (12) and is to separate a sample that has been injected into the analysis flow path (12) into components, a detector (8) that is provided on the analysis flow path (12) and is to detect sample components obtained by separation in the separation column (6), a system configuration specifier (26) that specifies a count and a connection structure of the liquid sending pumps (14) connected to the analysis flow path (12) as a system configuration, a condition holder (18) holding a condition that is for detection of a liquid sending failure of the liquid sending pump (14) and is preset in regard to each type of the system configuration, a condition determiner (20) that is configured to determine the condition corresponding to a system configuration specified by the system configuration specifier (26) from among conditions held by the condition holder (18), and a liquid sending failure detector (22) configured to detect a liquid sending failure of the liquid sending pump (14) using the condition determined by the condition determiner (20).
-
公开(公告)号：US20210172437A1
公开(公告)日：2021-06-10
申请号：US16768660
申请日：2018-06-20
Applicant: SHIMADZU CORPORATION
Inventor： Shinya IMAMURA , Keisuke OGAWA
Abstract: A liquid sending device includes a plunger pump, which performs an intake operation of liquid to and a discharge operation of liquid from a pump chamber and in which pressure in the pump chamber in a case where the intake operation is performed is lower compared to a case where the discharge operation is performed, a check valve that is provided at an inlet port, has a spherical valve element and a valve seat, and passively operates according to the pressure in the pump chamber in such a direction that the valve element is seated on or detached, a pressure sensor that detects the pressure, and an attachment detector that compares the pressure with a preset threshold value and detect attachment of the valve element to the valve seat in a case where the pressure in the pump chamber is equal to or lower than the threshold value.
-
公开(公告)号：US20200182235A1
公开(公告)日：2020-06-11
申请号：US16629421
申请日：2017-07-28
Applicant: SHIMADZU CORPORATION
Inventor： Jun YANAGIBAYASHI , Keisuke OGAWA
Abstract: A liquid feeding device includes a discharge channel, a pump part, a feeding pressure sensor, a non-discharge pressure sensor, a pre-compression part, and a pre-compression speed determination part. The pump part has plunger pumps connected in series or parallel. At least one of the plunger pumps is a closed pump in which communication with the discharge channel is disconnected during a non-discharge time. The pre-compression part causes the closed pump that is after the suction process for sucking the liquid into a pump chamber is completed and during the non-discharge time to execute a pre-compression process to perform a discharge operation until a non-discharge pressure is substantially the same as a feeding pressure based on output of the feeding pressure sensor and output of the non-discharge pressure sensor. The pre-compression speed determination part determines a pre-compression speed of the closed pump in the pre-compression process.
-
公开(公告)号：US20160313248A1
公开(公告)日：2016-10-27
申请号：US15135626
申请日：2016-04-22
Applicant: SHIMADZU CORPORATION
Inventor： Yusuke NAGAI , Keisuke OGAWA , Masato WATANABE , Kumiko JINGU , Masanori FUJIWARA , Tomoyuki YAMAZAKI
CPC classification number: G01N21/645 , G01N21/255 , G01N2021/641 , G01N2201/06153
Abstract: Light emitted from a light casting unit 1 including an LED as its light source is cast into a sample cell 2, and a photodetector 3 is placed at a position where the resultant passing light can be detected. The LED is driven to blink, and a data extracting section 71 extracts data obtained in a period in which the LED is turned on, as data (absorbance data) in which absorption of light by the sample solution is reflected. Moreover, in the case where a fluorescent component is contained in the sample solution, fluorescent light is emitted by the cast light serving as excitation light. Even after the excitation light ceases, the emission of the fluorescent light continues for a short time, and hence the data extracting section 71 extracts data obtained immediately after the LED is turned off, as data (fluorescence data) in which the fluorescent light is reflected. An absorbance computing section 72 calculates absorbance based on the absorbance data, and a fluorescence computing section 73 calculates fluorescence intensity based on the fluorescence data. Accordingly, it is possible to simultaneously perform an absorbance measurement and a fluorescence measurement on one sample while using one photodetector and thus simplifying the configuration of an optical system.
Abstract translation: 从包括LED作为其光源的光铸造单元1发射的光被投射到样品池2中，并且将光电检测器3放置在可以检测所得到的通过光的位置。 LED被驱动闪烁，并且数据提取部71提取在LED被接通的时段中获得的数据作为反映样品溶液的光吸收的数据（吸光度数据）。 此外，在样品溶液中含有荧光成分的情况下，作为激发光的投射光发出荧光。 即使在激发光停止之后，荧光的发射持续很短的时间，因此数据提取部71提取在关闭LED之后立即获得的数据作为反射荧光的数据（荧光数据） 。 吸光度计算部72基于吸光度数据计算吸光度，荧光运算部73基于荧光数据计算荧光强度。 因此，可以在使用一个光电检测器的同时对一个样品进行吸光度测量和荧光测量，从而简化了光学系统的结构。
-
公开(公告)号：US20230136667A1
公开(公告)日：2023-05-04
申请号：US17971604
申请日：2022-10-23
Applicant: SHIMADZU CORPORATION
Inventor： Keisuke OGAWA , Andy SASAKI , Kerry HILL , Timothy LEE
Abstract: A liquid chromatographic system includes a first cleaning pump that supplies a cleaning solution to a first valve, a selector valve connected to a first column and a second column, the selector valve switching an object to be connected to a detector that analyzes a separated sample between the first column and the second column, and a controller. The controller can have the first cleaning pump driven to clean the selector valve with the cleaning solution that flows through a first analysis flow path.
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.015 seconds)
