公开(公告)号：US20170252490A1

公开(公告)日：2017-09-07

申请号：US15503758

申请日：2015-09-23

Applicant: Sofradim Production

Inventor： Nicolas Prost ,  Delphine Petit ,  Xavier Bourges

IPC: A61L31/04 ,  A61L27/34 ,  A61F2/00 ,  A61L27/58 ,  C08J7/04 ,  C08J5/18 ,  A61L31/10 ,  A61L31/14

Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7%, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

公开(公告)号：US20160374792A1

公开(公告)日：2016-12-29

申请号：US15262165

申请日：2016-09-12

Applicant: Sofradim Production

Inventor： Julie Lecuivre ,  Xavier Bourges ,  Pierre Bailly

IPC: A61F2/00 ,  D06C7/00 ,  D04B21/20 ,  D04B21/12 ,  D04B21/14

CPC classification number: A61F2/0063 ,  A61F2002/0068 ,  A61F2220/0016 ,  A61F2240/001 ,  D04B21/12 ,  D04B21/14 ,  D04B21/20 ,  D06C7/00 ,  D10B2401/041 ,  D10B2403/0111 ,  D10B2501/0632 ,  D10B2509/08

Abstract: The present invention relates to a prosthetic knit based on at least a first yarn of biocompatible polymer material defining first and second opposite and openwork faces, and on at least a second biocompatible and heat-fusible monofilament yarn, forming barbs that protrude outwards from at least said first face and are obtained by melting loops generated by said second yarn, the chart followed for the knitting of said first and second yarns on a warp knitting machine having three guide bars B1, B2, B3 being the following, according to the ISO 11676 standard:—Bar B1: 1.0/0.1//—Bar B2: 1.0/7.7/6.6/7.7//—Bar B3: 2.1/5.5/3.4/0.0// said second yarn following the chart of bar B3. The present invention also relates to a process for manufacturing such a knit.

Abstract translation: 本发明涉及一种基于至少一种限定第一和第二相对和镂空面的生物相容性聚合物材料的第一纱线以及至少第二生物相容性和热熔性单丝纱线的复合编织物，形成从至少向外突出的倒钩 所述第一面是通过由所述第二纱线产生的线圈熔化而获得的，根据ISO 11676，在经编机上编织所述第一和第二纱线的图表，其具有三个导杆B1，B2，B3，如下所述 标准：-Bar B1：1.0 / 0.1 // - Bar B2：1.0 / 7.7 / 6.6 / 7.7 // - Bar B3：2.1 / 5.5 / 3.4 / 0.0 //所述第二根纱线遵循条B3的图表。 本发明还涉及一种制造这种针织物的方法。

公开(公告)号：US20210189616A1

公开(公告)日：2021-06-24

申请号：US17117083

申请日：2020-12-09

Applicant: SOFRADIM PRODUCTION

Inventor： Suzelei Montanari ,  Yves Bayon ,  Xavier Bourges ,  Delphine Petit

IPC: D04B21/12 ,  A61L27/50 ,  A61L27/56 ,  A61L27/54 ,  A61L27/34 ,  A61F2/00

Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

公开(公告)号：US10549015B2

公开(公告)日：2020-02-04

申请号：US15503758

申请日：2015-09-23

Applicant: Sofradim Production

Inventor： Nicolas Prost ,  Delphine Petit ,  Xavier Bourges

IPC: A61L31/04 ,  A61L31/10 ,  A61F2/00 ,  A61L27/34 ,  A61L27/58 ,  A61L31/14 ,  C08J5/18 ,  C08J7/04 ,  B29C41/12 ,  B29C41/22 ,  B29C41/24 ,  B29C41/02

Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7 %, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

公开(公告)号：US20190321155A1

公开(公告)日：2019-10-24

申请号：US16436979

申请日：2019-06-11

Applicant: Sofradim Production

Inventor： Julie Lecuivre ,  Xavier Bourges ,  Pierre Bailly

IPC: A61F2/00 ,  D04B21/14 ,  D04B21/12 ,  D04B21/20 ,  D06C7/00

Abstract: The present invention relates to a prosthetic knit based on at least a first yarn of biocompatible polymer material defining first and second opposite and openwork faces, and on at least a second biocompatible and heat-fusible monofilament yarn, forming barbs that protrude outwards from at least said first face and are obtained by melting loops generated by said second yarn, the chart followed for the knitting of said first and second yarns on a warp knitting machine having three guide bars B1, B2, B3 being the following, according to the ISO 11676 standard: Bar B1: 1.0/0.1// Bar B2: 1.0/7.7/6.6/7.78 Bar B3: 2.1/5.5/3.4/0.0//5 said second yam following the chart of bar B3. The present invention also relates to a process for manufacturing such a knit.

公开(公告)号：US20190008625A1

公开(公告)日：2019-01-10

申请号：US16128549

申请日：2018-09-12

Applicant: Sofradim Production

Inventor： Julie Lecuivre ,  Xavier Bourges

IPC: A61F2/00 ,  A61L27/34 ,  D04B21/12

Abstract: The present invention relates to a prosthesis (1) for the repair of an inguinal hernia, which prosthesis (1) is intended to be implanted by a posterior or open laparoscopic route and comprises: an openworked textile (2) made of biocompatible material, comprising a first face (2a) intended to be placed facing the biological tissues of the inguinal region, and a second face (2b) arranged opposite said first face and intended to be placed facing the peritoneum, said first face being provided with fastening means that are able to fix said textile in said biological tissues of the inguinal region, characterized in that at least a part of said second face (2b) is covered with a non-porous coating (7) composed of a material that is hydrosoluble at 37° C. and non-hydrosoluble at 25° C. The invention also relates to a method for producing such a prosthesis.

公开(公告)号：US20250018092A1

公开(公告)日：2025-01-16

申请号：US18813240

申请日：2024-08-23

Applicant: SOFRADIM PRODUCTION

Inventor： Nicolas Prost ,  Delphine Petit ,  Xavier Bourges

IPC: A61L31/04 ,  A61F2/00 ,  A61L27/34 ,  A61L27/58 ,  A61L31/10 ,  A61L31/14 ,  B29C41/02 ,  B29C41/12 ,  B29C41/22 ,  B29C41/24 ,  C08J5/18 ,  C08J7/04 ,  C08L89/06

Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7%, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

公开(公告)号：US20230039590A1

公开(公告)日：2023-02-09

申请号：US17968620

申请日：2022-10-18

Applicant: SOFRADIM PRODUCTION

Inventor： Julie Lecuivre ,  Xavier Bourges

IPC: A61F2/00 ,  D04B21/12 ,  A61L27/34

Abstract: The present invention relates to a prosthesis (1) for the repair of an inguinal hernia, which prosthesis (1) is intended to be implanted by a posterior or open laparoscopic route and comprises: an openworked textile (2) made of biocompatible material, comprising a first face (2a) intended to be placed facing the biological tissues of the inguinal region, and a second face (2b) arranged opposite said first face and intended to be placed facing the peritoneum, said first face being provided with fastening means that are able to fix said textile in said biological tissues of the inguinal region, characterized in that at least a part of said second face (2b) is covered with a non-porous coating (7) composed of a material that is hydrosoluble at 37° C. and non-hydrosoluble at 25° C. The invention also relates to a method for producing such a prosthesis.

公开(公告)号：US09445883B2

公开(公告)日：2016-09-20

申请号：US14366393

申请日：2012-12-27

Applicant: Sofradim Production

Inventor： Julie Lecuivre ,  Xavier Bourges ,  Pierre Bailly

IPC: A61F2/02 ,  A61F2/00 ,  D04B21/12 ,  D04B21/14 ,  D04B21/20 ,  D06C7/00

CPC classification number: A61F2/0063 ,  A61F2002/0068 ,  A61F2220/0016 ,  A61F2240/001 ,  D04B21/12 ,  D04B21/14 ,  D04B21/20 ,  D06C7/00 ,  D10B2401/041 ,  D10B2403/0111 ,  D10B2501/0632 ,  D10B2509/08

Abstract: The present invention relates to a prosthetic knit based on at least a first yarn of biocompatible polymer material defining first and second opposite and openwork faces, and on at least a second biocompatible and heat-fusible monofilament yarn, forming barbs that protrude outwards from at least said first face and are obtained by melting loops generated by said second yarn, the chart followed for the knitting of said first and second yarns on a warp knitting machine having three guide bars B1, B2, B3 being the following, according to the ISO 11676 standard:—Bar B1: 1.0/0.1//—Bar B2: 1.0/7.7/6.6/7.7//—Bar B3: 2.1/5.5/3.4/0.0// said second yarn following the chart of bar B3. The present invention also relates to a process for manufacturing such a knit.

Abstract translation: 本发明涉及一种基于至少一种限定第一和第二相对和镂空面的生物相容性聚合物材料的第一纱线以及至少第二生物相容性和热熔性单丝纱线的复合编织物，形成从至少向外突出的倒钩 所述第一面是通过由所述第二纱线产生的线圈熔化而获得的，根据ISO 11676，在经编机上编织所述第一和第二纱线的图表，其具有三个导杆B1，B2，B3，如下所述 标准：-Bar B1：1.0 / 0.1 // - Bar B2：1.0 / 7.7 / 6.6 / 7.7 // - Bar B3：2.1 / 5.5 / 3.4 / 0.0 //所述第二根纱线遵循条B3的图表。 本发明还涉及一种制造这种针织物的方法。

公开(公告)号：US11925543B2

公开(公告)日：2024-03-12

申请号：US17689910

申请日：2022-03-08

Applicant: SOFRADIM PRODUCTION

Inventor： Julie Lecuivre ,  Xavier Bourges ,  Pierre Bailly

IPC: A61F2/00 ,  D04B21/12 ,  D04B21/14 ,  D04B21/20 ,  D06C7/00

CPC classification number: A61F2/0063 ,  D04B21/12 ,  D04B21/14 ,  D04B21/20 ,  D06C7/00 ,  A61F2002/0068 ,  A61F2220/0016 ,  A61F2240/001 ,  D10B2401/041 ,  D10B2403/0111 ,  D10B2501/0632 ,  D10B2509/08

Abstract: The present invention relates to a prosthetic knit based on at least a first yarn of biocompatible polymer material defining first and second opposite and openwork faces, and on at least a second biocompatible and heat-fusible monofilament yarn, forming barbs that protrude outwards from at least said first face and are obtained by melting loops generated by said second yarn, the chart followed for the knitting of said first and second yarns on a warp knitting machine having three guide bars B1, B2, B3 being the following, according to the ISO 11676 standard:—Bar B1: 1.0/0.1//—Bar B2: 1.0/7.7/6.6/7.78—Bar B3: 2.1/5.5/3.4/0.0// said second yarn following the chart of bar B3. The present invention also relates to a process for manufacturing such a knit.