公开(公告)号：US10328178B2

公开(公告)日：2019-06-25

申请号：US15314557

申请日：2015-05-29

Applicant: Sofradim Production

Inventor： Aurelie Serrero ,  Robert Vestberg ,  Suzelei Montanari

IPC: C08L1/04 ,  C08L5/08 ,  A61L24/00 ,  A61L24/04 ,  A61L27/20 ,  A61L27/34 ,  A61L27/56 ,  A61L27/58 ,  A61L31/04 ,  A61L31/10 ,  A61L31/14

Abstract: The present invention relates to an implant (10) comprising: —a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.0 to 1, and —a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.

公开(公告)号：US20170239387A1

公开(公告)日：2017-08-24

申请号：US15314557

申请日：2015-05-29

Applicant: Sofradim Production

Inventor： Aurelie Serrero ,  Robert Vestberg ,  Suzelei Montanari

IPC: A61L27/20 ,  A61L27/56 ,  A61L31/10 ,  A61L31/14 ,  A61L31/04 ,  A61L27/58 ,  A61L27/34

CPC classification number: A61L27/20 ,  A61L24/0042 ,  A61L24/043 ,  A61L27/34 ,  A61L27/56 ,  A61L27/58 ,  A61L31/042 ,  A61L31/10 ,  A61L31/146 ,  A61L31/148 ,  A61L2400/04 ,  A61L2420/08 ,  C08L1/04 ,  C08L5/08

Abstract: The present invention relates to an implant (10) comprising: -a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.0 to 1, and -a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.

公开(公告)号：US20190275202A1

公开(公告)日：2019-09-12

申请号：US16424543

申请日：2019-05-29

Applicant: Sofradim Production

Inventor： Aurelie Serrero ,  Robert Vestberg ,  Suzelei Montanari

IPC: A61L27/20 ,  A61L31/14 ,  A61L27/56 ,  A61L24/00 ,  A61L27/58 ,  A61L24/04 ,  A61L27/34 ,  A61L31/10 ,  A61L31/04

Abstract: The present invention relates to an implant (10) comprising: a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.5 to 1, and a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.

公开(公告)号：US20180318057A1

公开(公告)日：2018-11-08

申请号：US15965826

申请日：2018-04-27

Applicant: Sofradim Production

Inventor： Pierre Bailly ,  Mylene Desorme ,  Suzelei Montanari

IPC: A61F2/00

CPC classification number: A61F2/0063 ,  A61F2002/0068 ,  A61F2210/0004 ,  A61F2210/0071 ,  A61F2230/0004 ,  A61F2230/0023 ,  A61F2240/001 ,  A61F2250/0018

Abstract: The present invention relates to a prosthesis (1) for repairing an inguinal hernia defect comprising: a piece (2) of biocompatible material having a preformed three-dimensional shape, including: a first portion (3) forming a partial spherical cap surface (8) shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall, a second portion (4) extending from an inferior edge of said first portion and forming a wavy-shaped wall (9), shaped and dimensioned so as to substantially conform to the shape of the psoas muscle, characterized in that said piece (2) further comprises: a third portion (5) forming an arched part (10) extending longitudinally in the inferior direction from a medial inferior corner (3a) of said first portion, said arched part extending radially substantially in the front direction, said third portion being intended to face the medial inferior area of the inguinal anatomy.

公开(公告)号：US20170165399A1

公开(公告)日：2017-06-15

申请号：US15116836

申请日：2015-02-18

Applicant: Sofradim Production

Inventor： Sebastien Francois ,  Nicolas Prost ,  Suzelei Montanari

IPC: A61L27/34 ,  A61L31/14 ,  D06N3/00 ,  A61L2/08 ,  D06B3/10 ,  A61L31/04 ,  A61L27/50

CPC classification number: A61L27/34 ,  A61L2/081 ,  A61L27/20 ,  A61L27/24 ,  A61L27/3687 ,  A61L27/50 ,  A61L31/042 ,  A61L31/044 ,  A61L31/14 ,  A61L2420/02 ,  D06B3/10 ,  D06B2700/27 ,  D06N3/00 ,  D06N2201/02 ,  D06N2203/02 ,  D06N2205/16 ,  D10B2331/04 ,  D10B2509/00

Abstract: A method for manufacturing an implantable film and a prosthesis comprising such a film The present invention relates to a method for manufacturing a non porous film intended to be implanted in the human body, said method comprising the following steps: preparation of a first film, called intermediate film, via gelling of a starting solution comprising at least one polymer selected in the group consisting of collagen, glycosaminoglycans, and mixtures thereof, immersion of said intermediate film in an alkaline composition comprising at least one C1-C4 alcohol, drying of the film obtained at the end of the immersing step. The invention also relates to a method for manufacturing a prosthesis comprising a textile support and such a film.

公开(公告)号：US20230301766A1

公开(公告)日：2023-09-28

申请号：US18205485

申请日：2023-06-02

Applicant: SOFRADIM PRODUCTION

Inventor： Pierre Bailly ,  Mylene Desorme ,  Suzelei Montanari

IPC: A61F2/00

CPC classification number: A61F2/0063 ,  A61F2230/0023 ,  A61F2230/0004 ,  A61F2250/0018 ,  A61F2230/0063 ,  A61F2002/0068 ,  A61F2210/0004 ,  A61F2210/0071 ,  A61F2240/001

Abstract: The present invention relates to a prosthesis (1) for repairing an inguinal hernia defect comprising:



a piece (2) of biocompatible material having a preformed three-dimensional shape, including:

a first portion (3) forming a partial spherical cap surface (8) shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall,
a second portion (4) extending from an inferior edge of said first portion and forming a wavy-shaped wall (9), shaped and dimensioned so as to substantially conform to the shape of the psoas muscle,


characterized in that said piece (2) further comprises:
a third portion (5) forming an arched part (10) extending longitudinally in the inferior direction from a medial inferior corner (3a) of said first portion, said arched part extending radially substantially in the front direction, said third portion being intended to face the medial inferior area of the inguinal anatomy.

公开(公告)号：US20200205957A1

公开(公告)日：2020-07-02

申请号：US16752756

申请日：2020-01-27

Applicant: Sofradim Production

Inventor： Suzelei Montanari ,  Pearl Rey

IPC: A61F2/00 ,  A61L31/10 ,  A61L31/14 ,  D04B21/12

Abstract: The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

公开(公告)号：US10675137B2

公开(公告)日：2020-06-09

申请号：US15965826

申请日：2018-04-27

Applicant: Sofradim Production

Inventor： Pierre Bailly ,  Mylene Desorme ,  Suzelei Montanari

IPC: A61F2/00

Abstract: The present invention relates to a prosthesis for repairing a inguinal hernia defect. The prosthesis includes a piece of biocompatible material having a preformed three-dimensional shape including: a first portion forming a partial spherical cap surface, shaped and dimensioned so as to substantially conform to the shape of the anterior abdominal wall; a second portion extending from an inferior edge of the first portion and forming a wavy-shaped wall, shaped and dimensioned so as to substantially conform to the shape of the psoas muscle; and a third portion forming an arched part extending longitudinally in the inferior direction from a medial inferior corner of the first portion, the arched part extending radially substantially in the front direction, the third portion being intended to face the medial inferior area of the inguinal anatomy.

公开(公告)号：US09750837B2

公开(公告)日：2017-09-05

申请号：US14421200

申请日：2013-09-25

Applicant: Sofradim Production

Inventor： Aurelie Serrero ,  Suzelei Montanari

IPC: A61L15/28 ,  A61F13/00 ,  A61L15/44 ,  A61L15/64 ,  C08L5/08 ,  C08L1/04 ,  B32B37/00 ,  B32B37/12 ,  B32B37/24 ,  B32B38/16

CPC classification number: A61L15/28 ,  A61L15/44 ,  A61L15/64 ,  A61L2400/04 ,  B32B37/0038 ,  B32B37/1284 ,  B32B37/24 ,  B32B38/162 ,  B32B2305/026 ,  B32B2317/18 ,  B32B2535/00 ,  B32B2555/00 ,  C08L1/04 ,  C08L5/08 ,  Y10T156/10

Abstract: The present invention relates to a haemostatic patch comprising a porous layer based on oxidized cellulose and a neutralized film based on chitosan, said film comprising a free face and a face fixed on one of the faces of the porous layer, and to the method of preparing said patch comprising the following steps: —a°) preparing a porous layer based on oxidized cellulose, —b°) preparing a film based on chitosan starting from an acidic aqueous solution of chitosan, —c°) fixing the film obtained in b°) on one face of the porous layer, —d°) neutralizing the film obtained in b°), —where step c°) can be carried out before or after step d°), characterized in that: the neutralizing step d°) comprises treatment of said film with a neutralizing composition comprising at least ethanol and ammonium hydroxide (NH4OH).

公开(公告)号：US20240279852A1

公开(公告)日：2024-08-22

申请号：US18651284

申请日：2024-04-30

Applicant: SOFRADIM PRODUCTION

Inventor： Suzelei Montanari ,  Yves Bayon ,  Xavier Bourges ,  Delphine Petit

IPC: D04B21/12 ,  A61F2/00 ,  A61F2/30 ,  A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56

CPC classification number: D04B21/12 ,  A61F2/0063 ,  A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L27/56 ,  A61F2/0077 ,  A61F2002/30322 ,  A61F2220/0016 ,  A61F2250/0026 ,  A61F2250/0031 ,  A61L2300/61 ,  D10B2403/0112 ,  D10B2501/0632 ,  D10B2509/08

Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.